IL61447A - Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation - Google Patents
Stable solutions of hydrogenated ergot alkaloids and heparin and their preparationInfo
- Publication number
- IL61447A IL61447A IL61447A IL6144780A IL61447A IL 61447 A IL61447 A IL 61447A IL 61447 A IL61447 A IL 61447A IL 6144780 A IL6144780 A IL 6144780A IL 61447 A IL61447 A IL 61447A
- Authority
- IL
- Israel
- Prior art keywords
- heparin
- preparation
- ergot alkaloids
- stable solutions
- hydrogenated ergot
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
- PBKVEOSEPXMKDN-LZHUFOCISA-N chembl2311030 Chemical compound CS(O)(=O)=O.CS(O)(=O)=O.CS(O)(=O)=O.CS(O)(=O)=O.C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C(=O)N[C@]3(C(=O)N4[C@H](C(N5CCC[C@H]5[C@]4(O)O3)=O)C(C)C)C(C)C)=C3C2=CNC3=C1.C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C(=O)N[C@]3(C(=O)N4[C@H](C(N5CCC[C@H]5[C@]4(O)O3)=O)C(C)CC)C(C)C)=C3C2=CNC3=C1.C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C(=O)N[C@]3(C(=O)N4[C@H](C(N5CCC[C@H]5[C@]4(O)O3)=O)CC(C)C)C(C)C)=C3C2=CNC3=C1.C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](C(N21)=O)(NC(=O)[C@H]1CN(C)[C@H]2[C@@H](C=3C=CC=C4NC=C(C=34)C2)C1)C(C)C)C1=CC=CC=C1 PBKVEOSEPXMKDN-LZHUFOCISA-N 0.000 title 1
- 229960002897 heparin Drugs 0.000 title 1
- 229920000669 heparin Polymers 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792945636 DE2945636A1 (de) | 1979-11-12 | 1979-11-12 | Stabile loesungen von hydrierten ergotalkaloiden bzw. ihren salzen und heparin bzw. seinen salzen sowie verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL61447A0 IL61447A0 (en) | 1980-12-31 |
| IL61447A true IL61447A (en) | 1983-11-30 |
Family
ID=6085779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL61447A IL61447A (en) | 1979-11-12 | 1980-11-10 | Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0028813B1 (cs) |
| JP (1) | JPS5686116A (cs) |
| AT (1) | AT371997B (cs) |
| AU (1) | AU535357B2 (cs) |
| BE (1) | BE886008A (cs) |
| CA (1) | CA1165692A (cs) |
| CH (1) | CH650930A5 (cs) |
| CY (1) | CY1332A (cs) |
| DE (2) | DE2945636A1 (cs) |
| DK (1) | DK155144C (cs) |
| FI (1) | FI72045C (cs) |
| GB (1) | GB2062468B (cs) |
| GR (1) | GR72128B (cs) |
| HK (1) | HK40386A (cs) |
| HU (1) | HU183244B (cs) |
| IE (1) | IE50372B1 (cs) |
| IL (1) | IL61447A (cs) |
| KE (1) | KE3623A (cs) |
| MY (1) | MY8500165A (cs) |
| PH (1) | PH22800A (cs) |
| PT (1) | PT72041B (cs) |
| ZA (1) | ZA807005B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3227122A1 (de) * | 1982-07-20 | 1984-01-26 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Stabile loesungen von mutterkornalkaloiden |
| CH656533A5 (de) * | 1982-12-10 | 1986-07-15 | Sandoz Ag | Therapeutisches praeparat enthaltend hydrierte ergotalkaloide und niedermolekulares heparin. |
| DE3432661A1 (de) * | 1984-09-05 | 1986-03-06 | Albert Prof. Dr. 6907 Nußloch Landsberger | Carcinom-therapeutikum |
| AT381232B (de) * | 1985-05-13 | 1986-09-10 | Kwizda Fa F Johann | Verfahren zur herstellung stabiler fluessiger loesungen von ergolinderivaten |
| RU2005101331A (ru) * | 2002-06-20 | 2006-01-20 | Новартис Консьюмер Хелс С.А. (Ch) | Назальная композиция, включающая мукополисахарид и пропиленгликоль |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2735587A1 (de) * | 1977-08-06 | 1979-02-15 | Sandoz Ag | Stabile loesungen und verfahren zu deren herstellung |
| DE2809618A1 (de) * | 1978-03-06 | 1979-09-20 | Sandoz Ag | Neues therapeutisches praeparat und verfahren zu dessen herstellung |
| DE2625403A1 (de) * | 1976-06-05 | 1977-12-08 | Sandoz Ag | Neue therapeutische mischung und verfahren zu deren herstellung |
| DE2555481C3 (de) * | 1975-12-10 | 1985-10-03 | Sandoz-Patent-GmbH, 7850 Lörrach | Herstellung stabiler Tropflösungen von hydrierten Ergotalkaloiden |
| DE2945677A1 (de) * | 1979-11-12 | 1981-05-21 | Sandoz-Patent-GmbH, 7850 Lörrach | Verwendung eines zweikammersystems zur verabreichung einer antithrombotischen mischung |
-
1979
- 1979-11-12 DE DE19792945636 patent/DE2945636A1/de not_active Withdrawn
-
1980
- 1980-11-03 BE BE1/10018A patent/BE886008A/fr not_active IP Right Cessation
- 1980-11-04 CH CH8192/80A patent/CH650930A5/de not_active IP Right Cessation
- 1980-11-05 FI FI803456A patent/FI72045C/fi not_active IP Right Cessation
- 1980-11-06 EP EP80106843A patent/EP0028813B1/de not_active Expired
- 1980-11-06 DE DE8080106843T patent/DE3068719D1/de not_active Expired
- 1980-11-10 GR GR63321A patent/GR72128B/el unknown
- 1980-11-10 AT AT0550480A patent/AT371997B/de not_active IP Right Cessation
- 1980-11-10 CY CY1332A patent/CY1332A/en unknown
- 1980-11-10 CA CA000364330A patent/CA1165692A/en not_active Expired
- 1980-11-10 PH PH24834A patent/PH22800A/en unknown
- 1980-11-10 IL IL61447A patent/IL61447A/xx unknown
- 1980-11-10 HU HU802692A patent/HU183244B/hu not_active IP Right Cessation
- 1980-11-10 GB GB8036009A patent/GB2062468B/en not_active Expired
- 1980-11-10 DK DK477880A patent/DK155144C/da not_active IP Right Cessation
- 1980-11-10 PT PT72041A patent/PT72041B/pt unknown
- 1980-11-11 JP JP15937680A patent/JPS5686116A/ja active Granted
- 1980-11-11 IE IE2340/80A patent/IE50372B1/en unknown
- 1980-11-11 AU AU64265/80A patent/AU535357B2/en not_active Ceased
- 1980-11-12 ZA ZA00807005A patent/ZA807005B/xx unknown
-
1985
- 1985-12-30 MY MY165/85A patent/MY8500165A/xx unknown
-
1986
- 1986-04-14 KE KE3623A patent/KE3623A/xx unknown
- 1986-05-29 HK HK403/86A patent/HK40386A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0028813A3 (en) | 1982-08-25 |
| MY8500165A (en) | 1985-12-31 |
| FI72045C (fi) | 1987-04-13 |
| PH22800A (en) | 1988-12-12 |
| CY1332A (en) | 1986-06-27 |
| IE50372B1 (en) | 1986-04-02 |
| AU535357B2 (en) | 1984-03-15 |
| ZA807005B (en) | 1982-06-30 |
| DK155144C (da) | 1989-07-03 |
| DK477880A (da) | 1981-05-13 |
| EP0028813B1 (de) | 1984-07-25 |
| HK40386A (en) | 1986-06-06 |
| HU183244B (en) | 1984-04-28 |
| GB2062468A (en) | 1981-05-28 |
| IE802340L (en) | 1981-05-12 |
| DK155144B (da) | 1989-02-20 |
| PT72041A (en) | 1980-12-01 |
| GB2062468B (en) | 1983-08-24 |
| IL61447A0 (en) | 1980-12-31 |
| CH650930A5 (de) | 1985-08-30 |
| AT371997B (de) | 1983-08-25 |
| ATA550480A (de) | 1983-01-15 |
| AU6426580A (en) | 1981-05-21 |
| PT72041B (en) | 1982-01-26 |
| GR72128B (cs) | 1983-09-16 |
| CA1165692A (en) | 1984-04-17 |
| EP0028813A2 (de) | 1981-05-20 |
| JPH021126B2 (cs) | 1990-01-10 |
| KE3623A (en) | 1986-05-16 |
| JPS5686116A (en) | 1981-07-13 |
| FI803456L (fi) | 1981-05-13 |
| BE886008A (fr) | 1981-05-04 |
| DE3068719D1 (en) | 1984-08-30 |
| DE2945636A1 (de) | 1981-05-21 |
| FI72045B (fi) | 1986-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2049377B (en) | Multipassage resistors and methods of making | |
| IL61447A (en) | Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation | |
| JPS52151715A (en) | Preparation of vincamine and apovincamine derivative | |
| ZA774020B (en) | Preparation of vincamine and related alkaloids | |
| AU514324B2 (en) | Preparation of alkaloids ofthe leurosine type | |
| GB2055370B (en) | Ergol-8-ene and ergoline derivatives | |
| JPS5428811A (en) | Hydrogenated ergot alkaloid and salt solution thereof and production | |
| IL49668A0 (en) | Stable solutions of ergot alkaloids,their preparation and pharmaceutical compositions comprising them | |
| ZA802582B (en) | Preparation of aryl-monourethanes and aryl-polyurethanes | |
| HK81085A (en) | Pharmaceutical compositions containing an ergot alkaloid and heparin | |
| JPS5661392A (en) | Ergot peptide alkaloids* their manufacture and medicinal composition | |
| PH13580A (en) | Preparation of rifamycin p and q derivatives | |
| AU570658B2 (en) | Pharmaceutical compositions of ergot alkaloids and heparin | |
| JPS57159783A (en) | Manufacture of ergot alkaloids | |
| AU3874378A (en) | Preparation of apovincamine from vincamine and epivincamine | |
| ZA79564B (en) | Novel derivatives of eburnamonine and related method of manufacturing | |
| GB2010245B (en) | Rifamycin derivatives and their preparation | |
| JPS56164195A (en) | Acid addition salt of ergot alkaloid and dihydro ergot alkaloid and manufacture thereof | |
| MY8400064A (en) | Pharmaceutical compositions containing an ergot alkaloid and heparin | |
| IL71884A0 (en) | New-o-substituted derivatives of(+)-cyanidan-3-ol and their preparation | |
| IL70068A0 (en) | Preparation of benzyl derivatives and benzyl derivatives employed therein |