JPS5686116A - Stable solution of hydrogenated ergot alkaloids - Google Patents

Stable solution of hydrogenated ergot alkaloids

Info

Publication number
JPS5686116A
JPS5686116A JP15937680A JP15937680A JPS5686116A JP S5686116 A JPS5686116 A JP S5686116A JP 15937680 A JP15937680 A JP 15937680A JP 15937680 A JP15937680 A JP 15937680A JP S5686116 A JPS5686116 A JP S5686116A
Authority
JP
Japan
Prior art keywords
stable solution
ergot alkaloids
hydrogenated ergot
hydrogenated
alkaloids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15937680A
Other languages
English (en)
Other versions
JPH021126B2 (ja
Inventor
Harutoman Fuorukaa
Otsuto Kaaruuhaintsu
Patsuto Ruudouitsuhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS5686116A publication Critical patent/JPS5686116A/ja
Publication of JPH021126B2 publication Critical patent/JPH021126B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP15937680A 1979-11-12 1980-11-11 Stable solution of hydrogenated ergot alkaloids Granted JPS5686116A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792945636 DE2945636A1 (de) 1979-11-12 1979-11-12 Stabile loesungen von hydrierten ergotalkaloiden bzw. ihren salzen und heparin bzw. seinen salzen sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
JPS5686116A true JPS5686116A (en) 1981-07-13
JPH021126B2 JPH021126B2 (ja) 1990-01-10

Family

ID=6085779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15937680A Granted JPS5686116A (en) 1979-11-12 1980-11-11 Stable solution of hydrogenated ergot alkaloids

Country Status (22)

Country Link
EP (1) EP0028813B1 (ja)
JP (1) JPS5686116A (ja)
AT (1) AT371997B (ja)
AU (1) AU535357B2 (ja)
BE (1) BE886008A (ja)
CA (1) CA1165692A (ja)
CH (1) CH650930A5 (ja)
CY (1) CY1332A (ja)
DE (2) DE2945636A1 (ja)
DK (1) DK155144C (ja)
FI (1) FI72045C (ja)
GB (1) GB2062468B (ja)
GR (1) GR72128B (ja)
HK (1) HK40386A (ja)
HU (1) HU183244B (ja)
IE (1) IE50372B1 (ja)
IL (1) IL61447A (ja)
KE (1) KE3623A (ja)
MY (1) MY8500165A (ja)
PH (1) PH22800A (ja)
PT (1) PT72041B (ja)
ZA (1) ZA807005B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533076A (ja) * 2002-06-20 2005-11-04 ノバルテイス・コンシユーマー・ヘルス・エス・アー ムコ多糖及びプロピレングリコールを含む鼻用組成物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3227122A1 (de) * 1982-07-20 1984-01-26 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Stabile loesungen von mutterkornalkaloiden
CH656533A5 (de) * 1982-12-10 1986-07-15 Sandoz Ag Therapeutisches praeparat enthaltend hydrierte ergotalkaloide und niedermolekulares heparin.
DE3432661A1 (de) * 1984-09-05 1986-03-06 Albert Prof. Dr. 6907 Nußloch Landsberger Carcinom-therapeutikum
AT381232B (de) * 1985-05-13 1986-09-10 Kwizda Fa F Johann Verfahren zur herstellung stabiler fluessiger loesungen von ergolinderivaten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2735587A1 (de) * 1977-08-06 1979-02-15 Sandoz Ag Stabile loesungen und verfahren zu deren herstellung
DE2625403A1 (de) * 1976-06-05 1977-12-08 Sandoz Ag Neue therapeutische mischung und verfahren zu deren herstellung
DE2809618A1 (de) * 1978-03-06 1979-09-20 Sandoz Ag Neues therapeutisches praeparat und verfahren zu dessen herstellung
DE2555481C3 (de) * 1975-12-10 1985-10-03 Sandoz-Patent-GmbH, 7850 Lörrach Herstellung stabiler Tropflösungen von hydrierten Ergotalkaloiden
DE2945677A1 (de) * 1979-11-12 1981-05-21 Sandoz-Patent-GmbH, 7850 Lörrach Verwendung eines zweikammersystems zur verabreichung einer antithrombotischen mischung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533076A (ja) * 2002-06-20 2005-11-04 ノバルテイス・コンシユーマー・ヘルス・エス・アー ムコ多糖及びプロピレングリコールを含む鼻用組成物

Also Published As

Publication number Publication date
ZA807005B (en) 1982-06-30
CH650930A5 (de) 1985-08-30
AT371997B (de) 1983-08-25
ATA550480A (de) 1983-01-15
HU183244B (en) 1984-04-28
PT72041A (en) 1980-12-01
IE50372B1 (en) 1986-04-02
DK155144B (da) 1989-02-20
DE2945636A1 (de) 1981-05-21
GB2062468A (en) 1981-05-28
IE802340L (en) 1981-05-12
FI72045B (fi) 1986-12-31
IL61447A0 (en) 1980-12-31
GR72128B (ja) 1983-09-16
IL61447A (en) 1983-11-30
DK477880A (da) 1981-05-13
PH22800A (en) 1988-12-12
AU535357B2 (en) 1984-03-15
FI803456L (fi) 1981-05-13
AU6426580A (en) 1981-05-21
BE886008A (fr) 1981-05-04
EP0028813A3 (en) 1982-08-25
CA1165692A (en) 1984-04-17
PT72041B (en) 1982-01-26
GB2062468B (en) 1983-08-24
DE3068719D1 (en) 1984-08-30
JPH021126B2 (ja) 1990-01-10
CY1332A (en) 1986-06-27
FI72045C (fi) 1987-04-13
MY8500165A (en) 1985-12-31
HK40386A (en) 1986-06-06
KE3623A (en) 1986-05-16
DK155144C (da) 1989-07-03
EP0028813A2 (de) 1981-05-20
EP0028813B1 (de) 1984-07-25

Similar Documents

Publication Publication Date Title
JPS55126123A (en) Holder of balllanddroller bearing
JPS5686116A (en) Stable solution of hydrogenated ergot alkaloids
AU514324B2 (en) Preparation of alkaloids ofthe leurosine type
ZA774020B (en) Preparation of vincamine and related alkaloids
NZ188073A (en) Stable aqueous solutions of hydrogenated ergopeptide alkaloids
HK15383A (en) Stable solutions of ergot alkaloids
JPS5371100A (en) Oxazolidinedion derivative of nichinichi alkaloid
GB2041915B (en) Preparation of bromo-p-terphenyl derivatives
GB1485738A (en) Ergot alkaloids
AU545645B2 (en) Ergot alkaloid
JPS5419291A (en) Center of lathe
JPS56158094A (en) Production of ergot alkaloid
JPS57159783A (en) Manufacture of ergot alkaloids
GR59327B (en) Preparation process of alkaloid derivatives
HK81085A (en) Pharmaceutical compositions containing an ergot alkaloid and heparin
IL59852A0 (en) Decolorization of pink grapefruit juide
AU529462B2 (en) Bromination of ergot alkaloids
JPS5427593A (en) Preparation of homopiperazine derivative
AU6302180A (en) Ergot alkaloid
JPS55111484A (en) Novel derivative of eburnamonine
NZ195030A (en) Preparation of 6 -methoxy-penam derivatives
JPS55343A (en) Manufacture of 33amino derivative of rifamycin s
JPS5646815A (en) Novel use of benzodiazepine derivative
JPS5795907A (en) Liquid medicine of ergot alkaloid
CS189485B1 (en) 1-substituted derivatives of ergoline