IL61447A - Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation - Google Patents

Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation

Info

Publication number
IL61447A
IL61447A IL61447A IL6144780A IL61447A IL 61447 A IL61447 A IL 61447A IL 61447 A IL61447 A IL 61447A IL 6144780 A IL6144780 A IL 6144780A IL 61447 A IL61447 A IL 61447A
Authority
IL
Israel
Prior art keywords
heparin
preparation
ergot alkaloids
stable solutions
hydrogenated ergot
Prior art date
Application number
IL61447A
Other versions
IL61447A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL61447A0 publication Critical patent/IL61447A0/en
Publication of IL61447A publication Critical patent/IL61447A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL61447A 1979-11-12 1980-11-10 Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation IL61447A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792945636 DE2945636A1 (en) 1979-11-12 1979-11-12 STABLE SOLUTIONS OF HYDRATED ERGOTAL CALOIDS OR YOUR SALTS AND HEPARIN OR ITS SALTS AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
IL61447A0 IL61447A0 (en) 1980-12-31
IL61447A true IL61447A (en) 1983-11-30

Family

ID=6085779

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61447A IL61447A (en) 1979-11-12 1980-11-10 Stable solutions of hydrogenated ergot alkaloids and heparin and their preparation

Country Status (22)

Country Link
EP (1) EP0028813B1 (en)
JP (1) JPS5686116A (en)
AT (1) AT371997B (en)
AU (1) AU535357B2 (en)
BE (1) BE886008A (en)
CA (1) CA1165692A (en)
CH (1) CH650930A5 (en)
CY (1) CY1332A (en)
DE (2) DE2945636A1 (en)
DK (1) DK155144C (en)
FI (1) FI72045C (en)
GB (1) GB2062468B (en)
GR (1) GR72128B (en)
HK (1) HK40386A (en)
HU (1) HU183244B (en)
IE (1) IE50372B1 (en)
IL (1) IL61447A (en)
KE (1) KE3623A (en)
MY (1) MY8500165A (en)
PH (1) PH22800A (en)
PT (1) PT72041B (en)
ZA (1) ZA807005B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3227122A1 (en) * 1982-07-20 1984-01-26 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim STABLE SOLUTIONS OF MOTHER CORNAL CALOIDS
CH656533A5 (en) * 1982-12-10 1986-07-15 Sandoz Ag THERAPEUTIC PREPARATION CONTAINING HYDRATED ERGOTAL CALOIDS AND LOW MOLECULAR HEPARINE.
DE3432661A1 (en) * 1984-09-05 1986-03-06 Albert Prof. Dr. 6907 Nußloch Landsberger CARCINOM THERAPEUTIC
AT381232B (en) * 1985-05-13 1986-09-10 Kwizda Fa F Johann METHOD FOR PRODUCING STABLE LIQUID SOLUTIONS OF ERGOL DERIVATIVES
PL373033A1 (en) * 2002-06-20 2005-08-08 Novartis Consumer Health S.A. Nasal compositions comprising a mucopolysaccharide and propylene glycol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2735587A1 (en) * 1977-08-06 1979-02-15 Sandoz Ag STABLE SOLUTIONS AND METHOD FOR THEIR PRODUCTION
DE2625403A1 (en) * 1976-06-05 1977-12-08 Sandoz Ag Antithrombotic association of medicaments - contains heparin and an ergoline-(8)-carboxylic acid peptidic amide esp. dihydroergotamine opt. with polyvinyl pyrrolidone
DE2809618A1 (en) * 1978-03-06 1979-09-20 Sandoz Ag NEW THERAPEUTIC PREPARATION AND METHOD FOR THE PRODUCTION THEREOF
DE2555481C3 (en) * 1975-12-10 1985-10-03 Sandoz-Patent-GmbH, 7850 Lörrach Production of stable drop solutions of hydrogenated ergot alkaloids
DE2945677A1 (en) * 1979-11-12 1981-05-21 Sandoz-Patent-GmbH, 7850 Lörrach Antithrombotic combination of di:hydro:ergotamine cpd. and heparin - administered using a two-chamber system syringe to avoid instability problems on prolonged storage

Also Published As

Publication number Publication date
ZA807005B (en) 1982-06-30
CH650930A5 (en) 1985-08-30
AT371997B (en) 1983-08-25
ATA550480A (en) 1983-01-15
HU183244B (en) 1984-04-28
PT72041A (en) 1980-12-01
IE50372B1 (en) 1986-04-02
DK155144B (en) 1989-02-20
DE2945636A1 (en) 1981-05-21
GB2062468A (en) 1981-05-28
IE802340L (en) 1981-05-12
FI72045B (en) 1986-12-31
IL61447A0 (en) 1980-12-31
GR72128B (en) 1983-09-16
DK477880A (en) 1981-05-13
JPS5686116A (en) 1981-07-13
PH22800A (en) 1988-12-12
AU535357B2 (en) 1984-03-15
FI803456L (en) 1981-05-13
AU6426580A (en) 1981-05-21
BE886008A (en) 1981-05-04
EP0028813A3 (en) 1982-08-25
CA1165692A (en) 1984-04-17
PT72041B (en) 1982-01-26
GB2062468B (en) 1983-08-24
DE3068719D1 (en) 1984-08-30
JPH021126B2 (en) 1990-01-10
CY1332A (en) 1986-06-27
FI72045C (en) 1987-04-13
MY8500165A (en) 1985-12-31
HK40386A (en) 1986-06-06
KE3623A (en) 1986-05-16
DK155144C (en) 1989-07-03
EP0028813A2 (en) 1981-05-20
EP0028813B1 (en) 1984-07-25

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