IL61382A - Azepinoindoles,their production and pharmaceutical compositions containing them - Google Patents

Azepinoindoles,their production and pharmaceutical compositions containing them

Info

Publication number
IL61382A
IL61382A IL61382A IL6138280A IL61382A IL 61382 A IL61382 A IL 61382A IL 61382 A IL61382 A IL 61382A IL 6138280 A IL6138280 A IL 6138280A IL 61382 A IL61382 A IL 61382A
Authority
IL
Israel
Prior art keywords
azepinoindoles
alkyl
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL61382A
Other languages
English (en)
Other versions
IL61382A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL61382A0 publication Critical patent/IL61382A0/xx
Publication of IL61382A publication Critical patent/IL61382A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL61382A 1979-11-02 1980-10-31 Azepinoindoles,their production and pharmaceutical compositions containing them IL61382A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH985279 1979-11-02

Publications (2)

Publication Number Publication Date
IL61382A0 IL61382A0 (en) 1980-12-31
IL61382A true IL61382A (en) 1984-02-29

Family

ID=4356374

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61382A IL61382A (en) 1979-11-02 1980-10-31 Azepinoindoles,their production and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US4478750A (de)
EP (1) EP0028381B1 (de)
JP (1) JPS5675493A (de)
AT (1) ATE12641T1 (de)
AU (1) AU6401480A (de)
DE (1) DE3070467D1 (de)
DK (1) DK465380A (de)
ES (1) ES496451A0 (de)
FI (1) FI803356A7 (de)
IL (1) IL61382A (de)
NZ (1) NZ195423A (de)
PT (1) PT72002B (de)
ZA (1) ZA806741B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649553A5 (de) * 1982-05-06 1985-05-31 Sandoz Ag Azepinoindole und verfahren zu deren herstellung.
DE3229215A1 (de) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
US4748247A (en) * 1986-10-21 1988-05-31 American Home Products Corporation 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]alkyl]alkyl]pyrido- and pyrazino-indole-1,3-dione derivatives as histamine H1 antagonists
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
US5616575A (en) * 1995-12-04 1997-04-01 Regents Of The University Of Minnesota Bioactive tricyclic ibogaine analogs
MY122278A (en) 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
WO2002004456A1 (en) * 2000-07-06 2002-01-17 Pharmacia & Upjohn Company SUBSTITUTED 2,3,7,8,9,10,11,12-OCTAHYDROAZEPINO[4,5-b]PYRANO[3,2-e]INDOLES
WO2002024700A2 (en) 2000-09-20 2002-03-28 Pharmacia & Upjohn Company SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES
DE60206636T2 (de) 2001-08-08 2006-06-22 Pharmacia & Upjohn Co. Llc, Kalamazoo THERAPEUTISCHE 1H-PYRIDO[4,3-b]INDOLE
WO2018064465A1 (en) 2016-09-29 2018-04-05 The Regents Of The University Of California Compounds for increasing neural plasticity
AU2020229779B9 (en) 2019-02-27 2025-09-18 The Regents Of The University Of California Azepino-indoles and other heterocycles for treating brain disorders
MX2024007221A (es) 2021-12-15 2024-08-27 Delix Therapeutics Inc Psicoplastogenos sustituidos con fenoxi y benciloxi y sus usos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445508A (de) * 1964-12-03 1967-10-31 Geigy Ag J R Verfahren zur Herstellung von neuen Indolderivaten
US3839357A (en) * 1966-05-10 1974-10-01 Upjohn Co 1,2,3,4,5,6-hexahydroazepino(4,5-b)indoles
US3553232A (en) * 1967-08-25 1971-01-05 Upjohn Co 4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones
US3652588A (en) * 1969-10-23 1972-03-28 Upjohn Co 6-alkyl-1 2 3 4 5 6-hexahydroazepino(4 5-b)indoles

Also Published As

Publication number Publication date
PT72002A (fr) 1980-11-01
PT72002B (fr) 1981-12-17
DK465380A (da) 1981-05-03
ES8205800A1 (es) 1982-06-16
IL61382A0 (en) 1980-12-31
ZA806741B (en) 1982-05-26
DE3070467D1 (en) 1985-05-15
ES496451A0 (es) 1982-06-16
EP0028381B1 (de) 1985-04-10
FI803356L (fi) 1981-05-03
US4478750A (en) 1984-10-23
ATE12641T1 (de) 1985-04-15
FI803356A7 (fi) 1981-05-03
JPS5675493A (en) 1981-06-22
EP0028381A2 (de) 1981-05-13
NZ195423A (en) 1984-07-06
EP0028381A3 (en) 1981-07-22
AU6401480A (en) 1981-05-07

Similar Documents

Publication Publication Date Title
IL96507A0 (en) Nitrogen-containing spirocycles and pharmaceutical compositions containing them
IL61382A (en) Azepinoindoles,their production and pharmaceutical compositions containing them
NZ220106A (en) Antidepressant heterocyclic compounds and pharmaceutical compositions
ES8604128A1 (es) Un procedimiento para la preparacion de nuevos derivados de bencenosulfonamida
DK291488A (da) Alkansulfonanilidderivater
GR3004353T3 (de)
EP0251014A3 (en) 2-trifluoromethyl benzimidazoles
IL84564A (en) Fused heterocyclic tetrahydroamino- quinolinols and related compounds, a process for their preparation and pharmaceutical compositions containing them
FI95247C (fi) Menetelmä lääkeaineina käytettävien 1,3-tiatsolidinien -karbonyylikarboksiamidien valmistamiseksi
ATE112563T1 (de) Diglycidyläther.
CS651286A2 (en) Herbicidni prostredek na bazi derivatu difenyl etherru a zpusob vyroby ucinne slozky
ATE82749T1 (de) 2-cyano-2-alkoximino-acetamide.
HUT43930A (en) Fungicides comprising naphthimidazolone derivatives as active substance and process for preparing the active substance
ZA818782B (en) Tricyclic compounds
DE3570877D1 (en) 3-amino-2,3-dihydro-1-benzoxepine compounds, process for their preparation and medicaments containing these compounds
ES538441A0 (es) Un metodo de preparar dibenz (b, f) oxepinas analgesicas