DK465380A - Fremgangsmaade til fremstilling af azepinderivater - Google Patents

Fremgangsmaade til fremstilling af azepinderivater

Info

Publication number
DK465380A
DK465380A DK465380A DK465380A DK465380A DK 465380 A DK465380 A DK 465380A DK 465380 A DK465380 A DK 465380A DK 465380 A DK465380 A DK 465380A DK 465380 A DK465380 A DK 465380A
Authority
DK
Denmark
Prior art keywords
alkyl
procedure
preparation
trifluoromethyl
alkoxy
Prior art date
Application number
DK465380A
Other languages
English (en)
Inventor
F Gadient
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK465380A publication Critical patent/DK465380A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK465380A 1979-11-02 1980-10-31 Fremgangsmaade til fremstilling af azepinderivater DK465380A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH985279 1979-11-02

Publications (1)

Publication Number Publication Date
DK465380A true DK465380A (da) 1981-05-03

Family

ID=4356374

Family Applications (1)

Application Number Title Priority Date Filing Date
DK465380A DK465380A (da) 1979-11-02 1980-10-31 Fremgangsmaade til fremstilling af azepinderivater

Country Status (13)

Country Link
US (1) US4478750A (da)
EP (1) EP0028381B1 (da)
JP (1) JPS5675493A (da)
AT (1) ATE12641T1 (da)
AU (1) AU6401480A (da)
DE (1) DE3070467D1 (da)
DK (1) DK465380A (da)
ES (1) ES496451A0 (da)
FI (1) FI803356L (da)
IL (1) IL61382A (da)
NZ (1) NZ195423A (da)
PT (1) PT72002B (da)
ZA (1) ZA806741B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649553A5 (de) * 1982-05-06 1985-05-31 Sandoz Ag Azepinoindole und verfahren zu deren herstellung.
DE3229215A1 (de) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
US4748247A (en) * 1986-10-21 1988-05-31 American Home Products Corporation 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]alkyl]alkyl]pyrido- and pyrazino-indole-1,3-dione derivatives as histamine H1 antagonists
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
US5616575A (en) * 1995-12-04 1997-04-01 Regents Of The University Of Minnesota Bioactive tricyclic ibogaine analogs
MY122278A (en) * 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
AU2001269781A1 (en) * 2000-07-06 2002-01-21 Pharmacia And Upjohn Company Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles
EP1319005A2 (en) * 2000-09-20 2003-06-18 PHARMACIA & UPJOHN COMPANY Substituted azepino[4,5-b]indoline derivatives
WO2003014118A1 (en) * 2001-08-08 2003-02-20 Pharmacia & Upjohn Company THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES
EP3931189A4 (en) 2019-02-27 2022-11-30 The Regents Of The University Of California AZEPINO-INDOLES AND OTHER HETEROCYCLES FOR TREATING BRAIN DISORDERS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445511A (de) * 1964-12-03 1967-10-31 Geigy Ag J R Verfahren zur Herstellung von neuen Indolderivaten
US3839357A (en) * 1966-05-10 1974-10-01 Upjohn Co 1,2,3,4,5,6-hexahydroazepino(4,5-b)indoles
US3553232A (en) * 1967-08-25 1971-01-05 Upjohn Co 4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones
US3652588A (en) * 1969-10-23 1972-03-28 Upjohn Co 6-alkyl-1 2 3 4 5 6-hexahydroazepino(4 5-b)indoles

Also Published As

Publication number Publication date
AU6401480A (en) 1981-05-07
PT72002A (fr) 1980-11-01
EP0028381B1 (en) 1985-04-10
EP0028381A2 (en) 1981-05-13
IL61382A (en) 1984-02-29
IL61382A0 (en) 1980-12-31
PT72002B (fr) 1981-12-17
FI803356L (fi) 1981-05-03
US4478750A (en) 1984-10-23
ZA806741B (en) 1982-05-26
ES8205800A1 (es) 1982-06-16
EP0028381A3 (en) 1981-07-22
ES496451A0 (es) 1982-06-16
NZ195423A (en) 1984-07-06
JPS5675493A (en) 1981-06-22
DE3070467D1 (en) 1985-05-15
ATE12641T1 (de) 1985-04-15

Similar Documents

Publication Publication Date Title
NO875440D0 (no) Fremgangsmaate for fremstilling av kalsiumuavhengig camp-fosfodiesterase-inhibitorantidepressivt middel.
FI906045A (fi) Kvaevehaltiga spirocykliska foereningar.
ATE32077T1 (de) 7-amino-azolo(1,5-a>-pyrimidine und diese enthaltende fungizide.
ES2074463T3 (es) Compuestos de nitrometileno, su preparacion y su uso como pesticidas.
DK465380A (da) Fremgangsmaade til fremstilling af azepinderivater
DE3360904D1 (de) A fungicidal indanylbenzamide
DE3776044D1 (de) Pyridazinon-derivate.
FI833784A0 (fi) 1,3,4,6,7,11b-hexahydro-7-aryl-2h-pyrazino/2,1-a/isokinoliner och foerfaranden foer framstaellning dessa
DE3667788D1 (de) Diphenyletherherbizide.
ES2099727T3 (es) 8-azabiciclo(3.2.1)octilalquiltiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.
ES2017493B3 (es) Herbicidas de difenil-eter.
ES2072334T3 (es) Derivados de 4,5,5a,6-tetrahidro-3h-isoxazolo(5,4,3-kl)acridinas, un procedimiento para su preparacion y su uso como medicamentos.
ES2077697T3 (es) Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
FI854343A (fi) Foerfarande foer framstaellning av 3-amino-2,3-dihydro-1-benzoxepinfoereningar.
IL82419A (en) 3-amino-dihydropyridines,their preparation and medicaments containing them
AR245701A1 (es) Derivados de sulfamoilurea herbicidamente activos y formulacion herbicida que los contiene

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment