AU2001269781A1 - Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles - Google Patents

Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles

Info

Publication number
AU2001269781A1
AU2001269781A1 AU2001269781A AU6978101A AU2001269781A1 AU 2001269781 A1 AU2001269781 A1 AU 2001269781A1 AU 2001269781 A AU2001269781 A AU 2001269781A AU 6978101 A AU6978101 A AU 6978101A AU 2001269781 A1 AU2001269781 A1 AU 2001269781A1
Authority
AU
Australia
Prior art keywords
octahydroazepino
pyrano
indoles
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001269781A
Inventor
Jian-Min Fu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU2001269781A1 publication Critical patent/AU2001269781A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
AU2001269781A 2000-07-06 2001-06-08 Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles Abandoned AU2001269781A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21628600P 2000-07-06 2000-07-06
US60216286 2000-07-06
PCT/US2001/018777 WO2002004456A1 (en) 2000-07-06 2001-06-08 SUBSTITUTED 2,3,7,8,9,10,11,12-OCTAHYDROAZEPINO[4,5-b]PYRANO[3,2-e]INDOLES

Publications (1)

Publication Number Publication Date
AU2001269781A1 true AU2001269781A1 (en) 2002-01-21

Family

ID=22806475

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001269781A Abandoned AU2001269781A1 (en) 2000-07-06 2001-06-08 Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles
AU2001271876A Abandoned AU2001271876A1 (en) 2000-07-06 2001-07-06 Azepino(4,5-b)pyrano(3,2-e)indoles

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001271876A Abandoned AU2001271876A1 (en) 2000-07-06 2001-07-06 Azepino(4,5-b)pyrano(3,2-e)indoles

Country Status (7)

Country Link
US (1) US6503899B2 (en)
EP (1) EP1296988A1 (en)
AR (1) AR028742A1 (en)
AU (2) AU2001269781A1 (en)
PE (1) PE20020194A1 (en)
TW (1) TWI248442B (en)
WO (2) WO2002004456A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001294606A1 (en) * 2000-09-20 2002-04-02 Brad A. Acker Substituted azepino(4,5b)indoline derivatives
US20030060462A1 (en) * 2001-08-06 2003-03-27 Hoffman Robert L. Therapeutic compounds
EP1792629A4 (en) 2004-08-25 2010-08-25 Takeda Pharmaceutical Preventives/remedies for stress urinary incontinence and method of screening the same
US8158617B2 (en) 2006-05-16 2012-04-17 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
JP5520051B2 (en) 2007-11-15 2014-06-11 武田薬品工業株式会社 Condensed pyridine derivatives and uses thereof
NZ586120A (en) 2008-01-11 2012-07-27 Albany Molecular Res Inc (1-azinone) -substituted pyridoindoles as mch antagonists
US8618299B2 (en) 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003005A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
EP2510949A4 (en) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutic agent for fibromyalgia
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
JPWO2019131902A1 (en) 2017-12-27 2020-12-10 武田薬品工業株式会社 Remedies for stress urinary incontinence and fecal incontinence
JP2022521789A (en) * 2019-02-27 2022-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Azepino-indole and other heterocyclic compounds for the treatment of brain disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR35044B (en) * 1966-05-10 1968-07-31 The Upjohn Company METHOD OF PREPARATION OF ORGANIC COMPOUNDS.
US3839357A (en) 1966-05-10 1974-10-01 Upjohn Co 1,2,3,4,5,6-hexahydroazepino(4,5-b)indoles
US3553232A (en) 1967-08-25 1971-01-05 Upjohn Co 4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones
US3622673A (en) * 1968-11-14 1971-11-23 Upjohn Co 4-(1,4,5,6-TETRAHYDROZEPINO 4,5-b INDOL-3(2H)-YL-BUTYROPHENON COMPOSITIONS AND PROCESS OF TREATMENT MENTAL OR EMOTIONAL DISORDERS
US3652588A (en) 1969-10-23 1972-03-28 Upjohn Co 6-alkyl-1 2 3 4 5 6-hexahydroazepino(4 5-b)indoles
US3676558A (en) 1970-08-28 1972-07-11 Upjohn Co Anorexigenic compositions comprising 6-alkyl-1,2,3,4,5,6-hexahydroazepino 4,5-indoles as active ingredient and process of treatment
US3776922A (en) * 1972-03-24 1973-12-04 J Epstein Indole carboxaldehydes
EP0028381B1 (en) * 1979-11-02 1985-04-10 Sandoz Ag Azepinoindoles, process for their production and pharmaceutical compositions containing them
AR023574A1 (en) * 1999-04-23 2002-09-04 Pharmacia & Upjohn Co Llc TETRACICLIC AZEPININDOL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THE USE OF SUCH COMPOUNDS TO PREPARE A MEDICINAL PRODUCT, AND INTERMEDIARIES

Also Published As

Publication number Publication date
PE20020194A1 (en) 2002-03-02
AR028742A1 (en) 2003-05-21
WO2002004456A1 (en) 2002-01-17
WO2002004457A8 (en) 2002-03-21
US20020022616A1 (en) 2002-02-21
EP1296988A1 (en) 2003-04-02
WO2002004457A1 (en) 2002-01-17
AU2001271876A1 (en) 2002-01-21
TWI248442B (en) 2006-02-01
US6503899B2 (en) 2003-01-07

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