FI803356L - Nya azepinoindoler deras framstaellning och dessa innehaollande farmaceutiska foereningar - Google Patents

Nya azepinoindoler deras framstaellning och dessa innehaollande farmaceutiska foereningar

Info

Publication number
FI803356L
FI803356L FI803356A FI803356A FI803356L FI 803356 L FI803356 L FI 803356L FI 803356 A FI803356 A FI 803356A FI 803356 A FI803356 A FI 803356A FI 803356 L FI803356 L FI 803356L
Authority
FI
Finland
Prior art keywords
preparation
alkyl
ingredients
inspection
pharmaceutical form
Prior art date
Application number
FI803356A
Other languages
English (en)
Inventor
Fulvio Gadient
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI803356L publication Critical patent/FI803356L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI803356A 1979-11-02 1980-10-27 Nya azepinoindoler deras framstaellning och dessa innehaollande farmaceutiska foereningar FI803356L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH985279 1979-11-02

Publications (1)

Publication Number Publication Date
FI803356L true FI803356L (fi) 1981-05-03

Family

ID=4356374

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803356A FI803356L (fi) 1979-11-02 1980-10-27 Nya azepinoindoler deras framstaellning och dessa innehaollande farmaceutiska foereningar

Country Status (13)

Country Link
US (1) US4478750A (fi)
EP (1) EP0028381B1 (fi)
JP (1) JPS5675493A (fi)
AT (1) ATE12641T1 (fi)
AU (1) AU6401480A (fi)
DE (1) DE3070467D1 (fi)
DK (1) DK465380A (fi)
ES (1) ES496451A0 (fi)
FI (1) FI803356L (fi)
IL (1) IL61382A (fi)
NZ (1) NZ195423A (fi)
PT (1) PT72002B (fi)
ZA (1) ZA806741B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH649553A5 (de) * 1982-05-06 1985-05-31 Sandoz Ag Azepinoindole und verfahren zu deren herstellung.
DE3229215A1 (de) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
US4748247A (en) * 1986-10-21 1988-05-31 American Home Products Corporation 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]alkyl]alkyl]pyrido- and pyrazino-indole-1,3-dione derivatives as histamine H1 antagonists
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9025890D0 (en) * 1990-11-28 1991-01-09 Lilly Industries Ltd Pharmaceutical compounds
US5616575A (en) * 1995-12-04 1997-04-01 Regents Of The University Of Minnesota Bioactive tricyclic ibogaine analogs
MY122278A (en) 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
AU2001269781A1 (en) * 2000-07-06 2002-01-21 Pharmacia And Upjohn Company Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles
AR035493A1 (es) 2000-09-20 2004-06-02 Upjohn Co Derivados de azepino (4,5b) indolina sustituidos, composicion farmaceutica y el uso de dichos derivados para preparar un medicamento
EP1414819B1 (en) 2001-08-08 2005-10-12 Pharmacia & Upjohn Company LLC THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES
MX2021010193A (es) 2019-02-27 2021-09-21 Univ California Azepino-indoles y otros heterociclos para el tratamiento de trastornos cerebrales.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445508A (de) * 1964-12-03 1967-10-31 Geigy Ag J R Verfahren zur Herstellung von neuen Indolderivaten
US3839357A (en) * 1966-05-10 1974-10-01 Upjohn Co 1,2,3,4,5,6-hexahydroazepino(4,5-b)indoles
US3553232A (en) * 1967-08-25 1971-01-05 Upjohn Co 4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones
US3652588A (en) * 1969-10-23 1972-03-28 Upjohn Co 6-alkyl-1 2 3 4 5 6-hexahydroazepino(4 5-b)indoles

Also Published As

Publication number Publication date
DE3070467D1 (en) 1985-05-15
PT72002A (fr) 1980-11-01
AU6401480A (en) 1981-05-07
EP0028381A2 (en) 1981-05-13
EP0028381B1 (en) 1985-04-10
IL61382A0 (en) 1980-12-31
DK465380A (da) 1981-05-03
PT72002B (fr) 1981-12-17
ZA806741B (en) 1982-05-26
ATE12641T1 (de) 1985-04-15
US4478750A (en) 1984-10-23
NZ195423A (en) 1984-07-06
EP0028381A3 (en) 1981-07-22
ES8205800A1 (es) 1982-06-16
JPS5675493A (en) 1981-06-22
ES496451A0 (es) 1982-06-16
IL61382A (en) 1984-02-29

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Legal Events

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FD Application lapsed

Owner name: SANDOZ AG