IL61316A - S-triazolo(3,4-a)phthalazin-6-amine derivatives and bronchodilating compositions comprising them - Google Patents
S-triazolo(3,4-a)phthalazin-6-amine derivatives and bronchodilating compositions comprising themInfo
- Publication number
- IL61316A IL61316A IL61316A IL6131680A IL61316A IL 61316 A IL61316 A IL 61316A IL 61316 A IL61316 A IL 61316A IL 6131680 A IL6131680 A IL 6131680A IL 61316 A IL61316 A IL 61316A
- Authority
- IL
- Israel
- Prior art keywords
- phthalazin
- triazolo
- amine derivatives
- bronchodilating
- compositions
- Prior art date
Links
- VHUAJJXCJFLQJX-UHFFFAOYSA-N N=1N=CN2C1C1=CC=CC=C1C(=N2)N Chemical class N=1N=CN2C1C1=CC=CC=C1C(=N2)N VHUAJJXCJFLQJX-UHFFFAOYSA-N 0.000 title 1
- 230000003182 bronchodilatating effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8907179A | 1979-10-29 | 1979-10-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL61316A0 IL61316A0 (en) | 1980-12-31 |
| IL61316A true IL61316A (en) | 1984-03-30 |
Family
ID=22215530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL61316A IL61316A (en) | 1979-10-29 | 1980-10-20 | S-triazolo(3,4-a)phthalazin-6-amine derivatives and bronchodilating compositions comprising them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0029130B1 (h) |
| JP (1) | JPS5679690A (h) |
| KR (1) | KR850001701B1 (h) |
| AR (2) | AR227651A1 (h) |
| AT (1) | ATE16808T1 (h) |
| AU (1) | AU536351B2 (h) |
| CA (1) | CA1144544A (h) |
| DE (1) | DE3071278D1 (h) |
| DK (1) | DK158353C (h) |
| ES (2) | ES8202555A1 (h) |
| FI (1) | FI70413C (h) |
| GB (1) | GB2061275B (h) |
| GR (1) | GR70309B (h) |
| IL (1) | IL61316A (h) |
| NO (1) | NO156011C (h) |
| NZ (1) | NZ195355A (h) |
| PT (1) | PT71952B (h) |
| ZA (1) | ZA806523B (h) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI81350C (fi) * | 1982-01-18 | 1990-10-10 | Lepetit Spa | Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat. |
| US4485106A (en) * | 1982-07-12 | 1984-11-27 | The Dow Chemical Company | Substituted tetrahydrotetrazolo[5,1-a]phthalazines |
| US4487930A (en) * | 1982-09-07 | 1984-12-11 | The Dow Chemical Company | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
| IT1194310B (it) * | 1983-07-12 | 1988-09-14 | Lepetit Spa | Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti |
| US4578464A (en) * | 1983-11-22 | 1986-03-25 | Merrell Dow Pharmaceuticals Inc. | 6-Hydroxyalkylamino-8-methyl-1,2,4-triazolo-[4,3-b]pyridazine and related compounds |
| US5011835A (en) * | 1990-02-07 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Substituted triazolopyridazines, pharmaceutical compositions and use |
| PH12012501361A1 (en) | 2009-12-31 | 2012-10-22 | Centro Nac De Investigaciones Oncologicas Cnio | Tricyclic compounds for use as kinase inhibitors |
| WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
| WO2013004984A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Tricyclic compounds for use as kinase inhibitors |
| WO2013005057A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | New compounds |
| WO2013005041A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Tricyclic heterocyclic compounds as kinase inhibitors |
| CN103694244B (zh) * | 2014-01-09 | 2016-03-30 | 郑州大学 | 3,6位取代-1,2,4-三氮唑并[3,4-a]酞嗪类化合物及其制备和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3708484A (en) * | 1970-10-16 | 1973-01-02 | Sandoz Ag | Amino and substituted amino-s-triazolo-(4,3-b)-pyridazines |
| US3915968A (en) * | 1973-09-21 | 1975-10-28 | Lepetit Spa | Triazolopyridazines |
| DE2418435A1 (de) * | 1974-04-17 | 1975-10-30 | Boehringer Mannheim Gmbh | Nitroimidazolyl-triazolo-pyridazine und verfahren zu ihrer herstellung |
| US4136182A (en) * | 1976-05-26 | 1979-01-23 | The Dow Chemical Company | Triazolopyridazines used to alleviate bronchial spasms |
| CA1080712A (en) * | 1976-09-22 | 1980-07-01 | Jay D. Albright | Hypotensive agents |
-
1980
- 1980-10-11 GR GR63143A patent/GR70309B/el unknown
- 1980-10-20 IL IL61316A patent/IL61316A/xx unknown
- 1980-10-21 AU AU63561/80A patent/AU536351B2/en not_active Ceased
- 1980-10-21 GB GB8033959A patent/GB2061275B/en not_active Expired
- 1980-10-22 PT PT71952A patent/PT71952B/pt not_active IP Right Cessation
- 1980-10-23 ZA ZA00806523A patent/ZA806523B/xx unknown
- 1980-10-23 NZ NZ195355A patent/NZ195355A/en unknown
- 1980-10-23 DE DE8080106450T patent/DE3071278D1/de not_active Expired
- 1980-10-23 AT AT80106450T patent/ATE16808T1/de not_active IP Right Cessation
- 1980-10-23 EP EP80106450A patent/EP0029130B1/en not_active Expired
- 1980-10-27 FI FI803355A patent/FI70413C/fi not_active IP Right Cessation
- 1980-10-28 ES ES496354A patent/ES8202555A1/es not_active Expired
- 1980-10-28 NO NO803218A patent/NO156011C/no unknown
- 1980-10-28 KR KR1019800004120A patent/KR850001701B1/ko not_active Expired
- 1980-10-28 CA CA000363395A patent/CA1144544A/en not_active Expired
- 1980-10-29 JP JP15199480A patent/JPS5679690A/ja active Granted
- 1980-10-29 DK DK457480A patent/DK158353C/da not_active IP Right Cessation
- 1980-10-30 AR AR283078A patent/AR227651A1/es active
-
1981
- 1981-11-06 ES ES506946A patent/ES8207178A1/es not_active Expired
-
1982
- 1982-02-12 AR AR288415A patent/AR227087A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| AR227087A1 (es) | 1982-09-15 |
| NO156011B (no) | 1987-03-30 |
| EP0029130B1 (en) | 1985-12-04 |
| FI803355L (fi) | 1981-04-30 |
| JPH0248558B2 (h) | 1990-10-25 |
| DK158353C (da) | 1990-10-01 |
| ZA806523B (en) | 1982-05-26 |
| NO803218L (no) | 1981-04-30 |
| GR70309B (h) | 1982-09-08 |
| GB2061275B (en) | 1983-08-10 |
| ES506946A0 (es) | 1982-09-01 |
| JPS5679690A (en) | 1981-06-30 |
| ATE16808T1 (de) | 1985-12-15 |
| ES496354A0 (es) | 1982-02-01 |
| FI70413C (fi) | 1986-09-19 |
| AU6356180A (en) | 1981-05-07 |
| NZ195355A (en) | 1984-09-28 |
| AU536351B2 (en) | 1984-05-03 |
| PT71952A (en) | 1980-11-01 |
| IL61316A0 (en) | 1980-12-31 |
| DK457480A (da) | 1981-04-30 |
| DE3071278D1 (en) | 1986-01-16 |
| CA1144544A (en) | 1983-04-12 |
| KR830004301A (ko) | 1983-07-09 |
| KR850001701B1 (ko) | 1985-11-26 |
| DK158353B (da) | 1990-05-07 |
| GB2061275A (en) | 1981-05-13 |
| ES8207178A1 (es) | 1982-09-01 |
| AR227651A1 (es) | 1982-11-30 |
| EP0029130A1 (en) | 1981-05-27 |
| ES8202555A1 (es) | 1982-02-01 |
| NO156011C (no) | 1987-07-08 |
| FI70413B (fi) | 1986-03-27 |
| PT71952B (en) | 1982-03-31 |
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