IL60261A - N-(6-substituted ergolinyl)-n',n'-diethylurea derivatives,a process for their manufacture and pharmaceutical compositions containing them - Google Patents
N-(6-substituted ergolinyl)-n',n'-diethylurea derivatives,a process for their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL60261A IL60261A IL60261A IL6026180A IL60261A IL 60261 A IL60261 A IL 60261A IL 60261 A IL60261 A IL 60261A IL 6026180 A IL6026180 A IL 6026180A IL 60261 A IL60261 A IL 60261A
- Authority
- IL
- Israel
- Prior art keywords
- manufacture
- pharmaceutical compositions
- compositions containing
- ergolinyl
- substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792924102 DE2924102A1 (de) | 1979-06-13 | 1979-06-13 | Neue (ergolin-yl)-n'.n'-diaethylharnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
DE19803016691 DE3016691A1 (de) | 1980-04-28 | 1980-04-28 | Neue (ergolin-yl)-n' .n'diaethylharnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel ii. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL60261A0 IL60261A0 (en) | 1980-09-16 |
IL60261A true IL60261A (en) | 1983-10-31 |
Family
ID=25779537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL60261A IL60261A (en) | 1979-06-13 | 1980-06-09 | N-(6-substituted ergolinyl)-n',n'-diethylurea derivatives,a process for their manufacture and pharmaceutical compositions containing them |
Country Status (14)
Country | Link |
---|---|
US (1) | US4379790A (es) |
EP (1) | EP0021206B1 (es) |
AU (1) | AU541679B2 (es) |
CA (1) | CA1140922A (es) |
CS (1) | CS223809B2 (es) |
DD (1) | DD151449A5 (es) |
DE (1) | DE3063869D1 (es) |
DK (1) | DK149059C (es) |
ES (1) | ES8101073A1 (es) |
HU (1) | HU184786B (es) |
IE (1) | IE49991B1 (es) |
IL (1) | IL60261A (es) |
SU (1) | SU965356A3 (es) |
YU (1) | YU41929B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982000463A1 (en) * | 1980-07-25 | 1982-02-18 | Ag Sandoz | Ergoline derivatives,method for their preparation,pharmaceutical compositions containing them and their therapeutic application |
CH644606A5 (de) * | 1980-09-23 | 1984-08-15 | Sandoz Ag | Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten. |
DE3101535A1 (de) * | 1981-01-14 | 1982-08-12 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
DE3135305C2 (de) * | 1981-09-03 | 1983-07-21 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen |
DE3151912A1 (de) * | 1981-12-23 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
CS231214B1 (en) * | 1982-03-12 | 1984-10-15 | Antonin Cerny | Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea |
DE3216870A1 (de) * | 1982-05-03 | 1983-11-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pharmazeutische zubereitungen mit zytostatischer wirkung |
DE3309493A1 (de) * | 1983-03-14 | 1984-09-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel |
DE3445784A1 (de) * | 1984-12-13 | 1986-06-26 | Schering AG, Berlin und Bergkamen, 1000 Berlin | Verfahren zur herstellung von ergolin-derivaten |
HU195810B (en) * | 1984-12-24 | 1988-07-28 | Sandoz Ag | Process for preparing new 8alpha-acyl-amino-ergoline derivatives and pharmaceutical compositions containing such compounds |
EP0208417A3 (en) * | 1985-06-12 | 1989-09-06 | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu | Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis |
DE3522894A1 (de) * | 1985-06-24 | 1987-01-02 | Schering Ag | Verwendung von tergurid als geriatrikum |
DE3528576A1 (de) * | 1985-08-06 | 1987-02-19 | Schering Ag | Verfahren zur herstellung von ergolin-thioharnstoffen |
DE3533675A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-brom-ergolinderivate |
DE3533672A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-substituierte ergolinderivate |
DK338789A (da) * | 1988-07-15 | 1990-01-16 | Schering Ag | 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf |
DE10043321B4 (de) | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
DE10226459A1 (de) * | 2002-06-13 | 2004-01-08 | Neurobiotec Gmbh | Verwendung von Dopamin-Partialagonisten zur Behandlung des Restless Legs Syndroms |
GB0307377D0 (en) * | 2003-03-31 | 2003-05-07 | Merad Pharmaceuticals Ltd | Ergoline derivatives |
EP2083008A1 (en) * | 2007-12-07 | 2009-07-29 | Axxonis Pharma AG | Ergoline derivatives as selective radical scavengers for neurons |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH430738A (de) * | 1962-09-05 | 1967-02-28 | Spofa Vereinigte Pharma Werke | Verfahren zur Herstellung von N-(D-1,6-Dimethyl-isoergolenyl-8)-N',N'-dialkyl-harnstoffen |
DE1212097B (de) * | 1962-09-05 | 1966-03-10 | Sdruzeni Podnikuu Pro Zdravotn | Verfahren zur Herstellung von N-[D-1, 6-Dimethylisoergolenyl-(8)]-N', N'-dialkylharnstoffen |
US3681497A (en) * | 1966-06-07 | 1972-08-01 | Spofa Vereinigte Pharma Werke | Therapeutic methods of employing hydrogen maleate salt of n-(d-6-methyl-8-isoergolenyl)-n{40 ,n{40 -diethyl-carbamide |
FR1536759A (fr) * | 1966-09-14 | 1968-08-16 | Spofa Vereinigte Pharma Werke | Procédé de préparation de la n-/d-6-méthyl-8-isoergolényl/-n', n'-diéthyl-urée |
CH573937A5 (es) * | 1971-08-05 | 1976-03-31 | Spofa Vereinigte Pharma Werke | |
US3920664A (en) * | 1972-07-21 | 1975-11-18 | Lilly Co Eli | D-2-halo-6-alkyl-8-substituted ergolines and related compounds |
JPS5448880A (en) * | 1977-09-02 | 1979-04-17 | Tetra Pak Int | Method of designing packaging laminate and packaging laminate |
-
1980
- 1980-06-07 EP EP80103177A patent/EP0021206B1/de not_active Expired
- 1980-06-07 DE DE8080103177T patent/DE3063869D1/de not_active Expired
- 1980-06-09 IL IL60261A patent/IL60261A/xx unknown
- 1980-06-09 AU AU59135/80A patent/AU541679B2/en not_active Ceased
- 1980-06-10 YU YU1544/80A patent/YU41929B/xx unknown
- 1980-06-11 DD DD80221757A patent/DD151449A5/de not_active IP Right Cessation
- 1980-06-12 CS CS804168A patent/CS223809B2/cs unknown
- 1980-06-12 CA CA000353888A patent/CA1140922A/en not_active Expired
- 1980-06-12 DK DK252680A patent/DK149059C/da not_active IP Right Cessation
- 1980-06-12 IE IE1210/80A patent/IE49991B1/en not_active IP Right Cessation
- 1980-06-12 HU HU801488A patent/HU184786B/hu not_active IP Right Cessation
- 1980-06-12 SU SU802930703A patent/SU965356A3/ru active
- 1980-06-13 ES ES492400A patent/ES8101073A1/es not_active Expired
-
1982
- 1982-01-06 US US06/337,355 patent/US4379790A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
SU965356A3 (ru) | 1982-10-07 |
DD151449A5 (de) | 1981-10-21 |
IE801210L (en) | 1980-12-13 |
YU41929B (en) | 1988-02-29 |
IE49991B1 (en) | 1986-01-22 |
DK252680A (da) | 1980-12-14 |
ES492400A0 (es) | 1980-12-16 |
ES8101073A1 (es) | 1980-12-16 |
IL60261A0 (en) | 1980-09-16 |
AU541679B2 (en) | 1985-01-17 |
HU184786B (en) | 1984-10-29 |
EP0021206B1 (de) | 1983-06-22 |
EP0021206A1 (de) | 1981-01-07 |
DK149059B (da) | 1986-01-06 |
DK149059C (da) | 1986-07-14 |
US4379790A (en) | 1983-04-12 |
CS223809B2 (en) | 1983-11-25 |
CA1140922A (en) | 1983-02-08 |
DE3063869D1 (en) | 1983-07-28 |
YU154480A (en) | 1983-09-30 |
AU5913580A (en) | 1980-12-18 |
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