DK149059C - Analogifremgangsmaade til fremstilling af (ergolin-yl)-n',n'-diethylurinstofderivater - Google Patents

Analogifremgangsmaade til fremstilling af (ergolin-yl)-n',n'-diethylurinstofderivater

Info

Publication number
DK149059C
DK149059C DK252680A DK252680A DK149059C DK 149059 C DK149059 C DK 149059C DK 252680 A DK252680 A DK 252680A DK 252680 A DK252680 A DK 252680A DK 149059 C DK149059 C DK 149059C
Authority
DK
Denmark
Prior art keywords
diethylurine
ergolin
ingredients
preparation
analogy procedure
Prior art date
Application number
DK252680A
Other languages
English (en)
Other versions
DK252680A (da
DK149059B (da
Inventor
Reinhard Horowski
Wolfgang Kehr
Gerhard Sauer
Ulrich Eder
Hans Peter Lorenz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19792924102 external-priority patent/DE2924102A1/de
Priority claimed from DE19803016691 external-priority patent/DE3016691A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK252680A publication Critical patent/DK252680A/da
Publication of DK149059B publication Critical patent/DK149059B/da
Application granted granted Critical
Publication of DK149059C publication Critical patent/DK149059C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK252680A 1979-06-13 1980-06-12 Analogifremgangsmaade til fremstilling af (ergolin-yl)-n',n'-diethylurinstofderivater DK149059C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19792924102 DE2924102A1 (de) 1979-06-13 1979-06-13 Neue (ergolin-yl)-n'.n'-diaethylharnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE2924102 1979-06-13
DE3016691 1980-04-28
DE19803016691 DE3016691A1 (de) 1980-04-28 1980-04-28 Neue (ergolin-yl)-n' .n'diaethylharnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel ii.

Publications (3)

Publication Number Publication Date
DK252680A DK252680A (da) 1980-12-14
DK149059B DK149059B (da) 1986-01-06
DK149059C true DK149059C (da) 1986-07-14

Family

ID=25779537

Family Applications (1)

Application Number Title Priority Date Filing Date
DK252680A DK149059C (da) 1979-06-13 1980-06-12 Analogifremgangsmaade til fremstilling af (ergolin-yl)-n',n'-diethylurinstofderivater

Country Status (14)

Country Link
US (1) US4379790A (da)
EP (1) EP0021206B1 (da)
AU (1) AU541679B2 (da)
CA (1) CA1140922A (da)
CS (1) CS223809B2 (da)
DD (1) DD151449A5 (da)
DE (1) DE3063869D1 (da)
DK (1) DK149059C (da)
ES (1) ES8101073A1 (da)
HU (1) HU184786B (da)
IE (1) IE49991B1 (da)
IL (1) IL60261A (da)
SU (1) SU965356A3 (da)
YU (1) YU41929B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH654838A5 (fr) * 1980-07-25 1986-03-14 Sandoz Ag Ergolinderivate, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen.
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3135305C2 (de) * 1981-09-03 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
CS231214B1 (en) * 1982-03-12 1984-10-15 Antonin Cerny Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
DE3445784A1 (de) * 1984-12-13 1986-06-26 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von ergolin-derivaten
NL8503426A (nl) * 1984-12-24 1986-07-16 Sandoz Ag 8alfa-acylamino-ergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
DE3528576A1 (de) * 1985-08-06 1987-02-19 Schering Ag Verfahren zur herstellung von ergolin-thioharnstoffen
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE10066158B4 (de) * 2000-08-24 2007-08-09 Neurobiotec Gmbh Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system
DE10053397A1 (de) * 2000-10-20 2002-05-02 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
DE10064453A1 (de) * 2000-12-16 2002-07-04 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
DE10226459A1 (de) * 2002-06-13 2004-01-08 Neurobiotec Gmbh Verwendung von Dopamin-Partialagonisten zur Behandlung des Restless Legs Syndroms
GB0307377D0 (en) * 2003-03-31 2003-05-07 Merad Pharmaceuticals Ltd Ergoline derivatives
EP2067780A1 (en) * 2007-12-07 2009-06-10 Axxonis Pharma AG Ergoline derivatives as selective radical scavengers for neurons

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1212097B (de) * 1962-09-05 1966-03-10 Sdruzeni Podnikuu Pro Zdravotn Verfahren zur Herstellung von N-[D-1, 6-Dimethylisoergolenyl-(8)]-N', N'-dialkylharnstoffen
CH430738A (de) * 1962-09-05 1967-02-28 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von N-(D-1,6-Dimethyl-isoergolenyl-8)-N',N'-dialkyl-harnstoffen
US3681497A (en) * 1966-06-07 1972-08-01 Spofa Vereinigte Pharma Werke Therapeutic methods of employing hydrogen maleate salt of n-(d-6-methyl-8-isoergolenyl)-n{40 ,n{40 -diethyl-carbamide
FR1536759A (fr) * 1966-09-14 1968-08-16 Spofa Vereinigte Pharma Werke Procédé de préparation de la n-/d-6-méthyl-8-isoergolényl/-n', n'-diéthyl-urée
CH573937A5 (da) * 1971-08-05 1976-03-31 Spofa Vereinigte Pharma Werke
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
JPS5448880A (en) * 1977-09-02 1979-04-17 Tetra Pak Int Method of designing packaging laminate and packaging laminate

Also Published As

Publication number Publication date
ES492400A0 (es) 1980-12-16
DK252680A (da) 1980-12-14
IE801210L (en) 1980-12-13
YU154480A (en) 1983-09-30
YU41929B (en) 1988-02-29
EP0021206B1 (de) 1983-06-22
EP0021206A1 (de) 1981-01-07
US4379790A (en) 1983-04-12
ES8101073A1 (es) 1980-12-16
AU5913580A (en) 1980-12-18
SU965356A3 (ru) 1982-10-07
DE3063869D1 (en) 1983-07-28
HU184786B (en) 1984-10-29
IE49991B1 (en) 1986-01-22
AU541679B2 (en) 1985-01-17
DD151449A5 (de) 1981-10-21
CA1140922A (en) 1983-02-08
IL60261A (en) 1983-10-31
CS223809B2 (en) 1983-11-25
DK149059B (da) 1986-01-06
IL60261A0 (en) 1980-09-16

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