IL58065A - Furyl substituted polyene carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Furyl substituted polyene carboxylic acid derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL58065A IL58065A IL58065A IL5806579A IL58065A IL 58065 A IL58065 A IL 58065A IL 58065 A IL58065 A IL 58065A IL 5806579 A IL5806579 A IL 5806579A IL 58065 A IL58065 A IL 58065A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- preparation
- carboxylic acid
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 125000002541 furyl group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 polyene carboxylic acid derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 208000005243 Chondrosarcoma Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Polyethers (AREA)
- Polyesters Or Polycarbonates (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/936,467 US4216312A (en) | 1978-08-24 | 1978-08-24 | Furyl substituted polyenes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL58065A0 IL58065A0 (en) | 1979-12-30 |
| IL58065A true IL58065A (en) | 1983-09-30 |
Family
ID=25468687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL58065A IL58065A (en) | 1978-08-24 | 1979-08-17 | Furyl substituted polyene carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4216312A (xx) |
| EP (1) | EP0008665B1 (xx) |
| JP (1) | JPS5531089A (xx) |
| AT (1) | ATE3768T1 (xx) |
| AU (1) | AU526146B2 (xx) |
| CA (1) | CA1163643A (xx) |
| DE (1) | DE2965657D1 (xx) |
| DK (1) | DK158946C (xx) |
| IE (1) | IE48808B1 (xx) |
| IL (1) | IL58065A (xx) |
| NZ (1) | NZ191346A (xx) |
| PH (1) | PH16278A (xx) |
| ZA (1) | ZA794341B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4299995A (en) * | 1979-05-10 | 1981-11-10 | Hoffmann-La Roche Inc. | Fluorinated polyenes |
| US4395575A (en) * | 1975-11-14 | 1983-07-26 | Hoffmann-La Roche, Inc. | 5(Halophenyl)-2-fluoro-pentadienals |
| US4335248A (en) * | 1975-11-14 | 1982-06-15 | Hoffmann-La Roche Inc. | Fluorinated polyenes |
| US6992108B1 (en) * | 1991-12-18 | 2006-01-31 | The Salk Institute For Biological Studies | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor |
| US7056954B2 (en) * | 1991-12-18 | 2006-06-06 | The Salk Institute For Biological Studies | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor |
| US5968989A (en) * | 1991-12-18 | 1999-10-19 | The Salk Institute For Biological Studies | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor |
| JP2003055367A (ja) * | 2001-08-15 | 2003-02-26 | Kuraray Co Ltd | ３−ホルミルフラン類の製造方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH582668A5 (xx) * | 1973-08-10 | 1976-12-15 | Hoffmann La Roche | |
| US3948758A (en) * | 1974-06-17 | 1976-04-06 | Mobil Oil Corporation | Production of alkyl aromatic hydrocarbons |
| US4086420A (en) * | 1975-01-23 | 1978-04-25 | Sagami Chemical Research Center | Thioprene or furan derivatives and process for preparation thereof |
| AT351515B (de) | 1976-12-20 | 1979-07-25 | Hoffmann La Roche | Verfahren zur herstellung von neuen polyenver- bindungen |
| DE2649138A1 (de) * | 1975-10-30 | 1977-05-12 | Hoffmann La Roche | Verfahren zur herstellung von polyenverbindungen |
| US4061656A (en) * | 1975-11-14 | 1977-12-06 | Hoffmann-La Roche Inc. | Polyene compounds |
| JPS5313029A (en) * | 1976-07-20 | 1978-02-06 | Mitsubishi Electric Corp | Igniter for internal combustion engine |
| CA1111441A (en) * | 1976-12-20 | 1981-10-27 | Werner Bollag | Polyene compounds |
| LU77254A1 (xx) | 1977-05-04 | 1979-01-18 |
-
1978
- 1978-08-24 US US05/936,467 patent/US4216312A/en not_active Expired - Lifetime
-
1979
- 1979-07-27 AT AT79102681T patent/ATE3768T1/de not_active IP Right Cessation
- 1979-07-27 EP EP79102681A patent/EP0008665B1/en not_active Expired
- 1979-07-27 DE DE7979102681T patent/DE2965657D1/de not_active Expired
- 1979-07-30 CA CA000332793A patent/CA1163643A/en not_active Expired
- 1979-08-17 ZA ZA00794341A patent/ZA794341B/xx unknown
- 1979-08-17 IL IL58065A patent/IL58065A/xx unknown
- 1979-08-17 NZ NZ191346A patent/NZ191346A/en unknown
- 1979-08-22 JP JP10612379A patent/JPS5531089A/ja active Granted
- 1979-08-22 PH PH22943A patent/PH16278A/en unknown
- 1979-08-23 DK DK352879A patent/DK158946C/da not_active IP Right Cessation
- 1979-08-23 IE IE1613/79A patent/IE48808B1/en not_active IP Right Cessation
- 1979-08-24 AU AU50266/79A patent/AU526146B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US4216312A (en) | 1980-08-05 |
| NZ191346A (en) | 1984-03-30 |
| IE791613L (en) | 1980-02-24 |
| IE48808B1 (en) | 1985-05-29 |
| AU526146B2 (en) | 1982-12-16 |
| AU5026679A (en) | 1980-02-28 |
| CA1163643A (en) | 1984-03-13 |
| DK352879A (da) | 1980-03-31 |
| DK158946C (da) | 1991-01-21 |
| DE2965657D1 (en) | 1983-07-21 |
| ATE3768T1 (de) | 1983-06-15 |
| JPS636548B2 (xx) | 1988-02-10 |
| PH16278A (en) | 1983-08-26 |
| ZA794341B (en) | 1980-08-27 |
| IL58065A0 (en) | 1979-12-30 |
| DK158946B (da) | 1990-08-06 |
| EP0008665B1 (en) | 1983-06-15 |
| JPS5531089A (en) | 1980-03-05 |
| EP0008665A1 (en) | 1980-03-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3534564C2 (de) | Naphthalinderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische und kosmetische Mittel | |
| US4677120A (en) | Topical prodrugs for treatment of acne and skin diseases | |
| DE3850109T2 (de) | 13-trans-retinsäureester. | |
| NL190160C (nl) | Piperazinecarboxamide- en -carbothioamidederivaten, werkwijze ter bereiding daarvan, alsmede farmaceutisch preparaat dat een dergelijk derivaat omvat. | |
| DE2925945C2 (xx) | ||
| FR2395263A1 (fr) | Derives d'acides thiadiazole-1, 2, 3 carboxyliques-5 utilisables comme matieres actives de produits herbicides | |
| HK1006841A1 (en) | Substituted heterocyclic carboxylic acid amides their preparation and their use as medicaments | |
| RU95112575A (ru) | Соль арилпропионовой кислоты, способ ее получения и фармацевтическая композиция | |
| ES499870A0 (es) | Un procedimiento para la preparacion de derivados de indano | |
| DE3711546C2 (de) | Aromatische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische und kosmetische Zubereitungen | |
| DE69704093T2 (de) | Biaryl heterocyclische Verbindungen und ihre Verwendung in der Human- oder Tiermedizin und in der Kosmetik | |
| IL58065A (en) | Furyl substituted polyene carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| GR71716B (xx) | ||
| KR960031422A (ko) | 신규한 레티노이드 | |
| US4472430A (en) | Alpha-alkyl polyolefinic carboxylic acids and derivatives thereof useful in the treatment of psoriasis | |
| KR950000141A (ko) | 피부병 치료용 약제조성물 제조를 위한 방향족산을 함유한 l- 카르니틴 o-에스테르의 용도 | |
| US4654354A (en) | Retinoic acid derivatives, process for their preparation and pharmaceutical and cosmetic compositions containing them | |
| ES427079A1 (es) | Un metodo de preparacion de fenotiazidas sustituidas por fluor en la posicion 7. | |
| EP0002533B1 (de) | Verwendung von Retinoiden als Arzneimittel | |
| EP0009777B1 (de) | Retinsäure- und 7,8-Dehydro-retinsäure-N-(carboxy)-phenyl-amide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel | |
| AU605772B2 (en) | Topical prodrugs for treatment of acne and skin diseases | |
| ES8105254A1 (es) | Un procedimiento para la preparacion de acido 2-(4-dimetil- vinilfenil) propionico | |
| FI896228A0 (fi) | Analogiamenetelmä valmistaa lääkeaineina käyttökelpoisia uusia karboksimidiamidijohdannaisia tai niiden farmaseuttisesti sopivia happoadditiosuoloja | |
| KR880001561A (ko) | 유효한 치료성을 갖는 신규 8-(저급알킬)비시클로[4.2.0] 옥탄 유도체 | |
| RU95107145A (ru) | Производные пиридобензоксадиазинкарбоновой кислоты, смесь их изомеров или отдельные изомеры, их фармацевтически приемлемые гидраты и соли, промежуточные продукты для их получения и фармацевтическая композиция с антибактериальной активностью на их основе |