IL56731A - D-alpha-(4-hydroxy-5-pyrimidinyl)-ureido)-penicillins and salts thereof,their preparation and pharmaceutical compositions and foodstuffs containing them - Google Patents

D-alpha-(4-hydroxy-5-pyrimidinyl)-ureido)-penicillins and salts thereof,their preparation and pharmaceutical compositions and foodstuffs containing them

Info

Publication number
IL56731A
IL56731A IL56731A IL5673179A IL56731A IL 56731 A IL56731 A IL 56731A IL 56731 A IL56731 A IL 56731A IL 5673179 A IL5673179 A IL 5673179A IL 56731 A IL56731 A IL 56731A
Authority
IL
Israel
Prior art keywords
penicillins
ureido
pyrimidinyl
alpha
hydroxy
Prior art date
Application number
IL56731A
Other languages
English (en)
Other versions
IL56731A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782808153 external-priority patent/DE2808153A1/de
Priority claimed from DE19782851270 external-priority patent/DE2851270A1/de
Priority claimed from DE19782851226 external-priority patent/DE2851226A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL56731A0 publication Critical patent/IL56731A0/xx
Publication of IL56731A publication Critical patent/IL56731A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL56731A 1978-02-25 1979-02-23 D-alpha-(4-hydroxy-5-pyrimidinyl)-ureido)-penicillins and salts thereof,their preparation and pharmaceutical compositions and foodstuffs containing them IL56731A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19782808153 DE2808153A1 (de) 1978-02-25 1978-02-25 Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE19782851270 DE2851270A1 (de) 1978-11-27 1978-11-27 Neue penicilline, ihre salze, verfahren zu ihrer herstellung, ihre verwendung und diese verbindungen enthaltende arzneimittel
DE19782851226 DE2851226A1 (de) 1978-11-27 1978-11-27 Neue penicilline, ihre salze, verfahren zu ihrer herstellung, ihre verwendung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
IL56731A0 IL56731A0 (en) 1979-05-31
IL56731A true IL56731A (en) 1982-04-30

Family

ID=27187467

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56731A IL56731A (en) 1978-02-25 1979-02-23 D-alpha-(4-hydroxy-5-pyrimidinyl)-ureido)-penicillins and salts thereof,their preparation and pharmaceutical compositions and foodstuffs containing them

Country Status (18)

Country Link
US (2) US4241056A (fi)
EP (1) EP0003814B1 (fi)
JP (1) JPS6058237B2 (fi)
AT (1) AT364459B (fi)
AU (1) AU522042B2 (fi)
CA (1) CA1132539A (fi)
DE (1) DE2961571D1 (fi)
DK (1) DK77479A (fi)
ES (1) ES477520A1 (fi)
FI (1) FI68237C (fi)
GR (1) GR66677B (fi)
HU (1) HU180997B (fi)
IE (1) IE48323B1 (fi)
IL (1) IL56731A (fi)
NO (1) NO790628L (fi)
NZ (1) NZ189754A (fi)
PT (1) PT69279A (fi)
YU (1) YU44979A (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2910190A1 (de) * 1979-03-15 1980-10-02 Thomae Gmbh Dr K Neue penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3028451A1 (de) * 1980-07-26 1982-04-08 Dr. Karl Thomae Gmbh, 7950 Biberach Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0049968A1 (en) * 1980-10-15 1982-04-21 Beecham Group Plc Pharmaceutical compositions
DE3039243A1 (de) * 1980-10-17 1982-05-27 Dr. Karl Thomae Gmbh, 7950 Biberach Antibiotisch wirksame arzneimittelkombination
GR78166B (fi) * 1981-05-04 1984-09-26 Chinoin Gyogyszer Es Vegyeszet
EP0067612A1 (en) * 1981-06-12 1982-12-22 Beecham Group Plc Penicillin derivatives
EP0067610A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Penicillins, a process for their preparation and compositions containing them
DE3134776A1 (de) * 1981-09-02 1983-03-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 6(alpha)-methoxy-penicilline, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0091755A1 (en) * 1982-04-03 1983-10-19 Beecham Group Plc Penicillin derivatives, a process for their preparation and compositions containing them
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
US4789063A (en) * 1986-10-30 1988-12-06 International Container Systems, Inc. Spacer tray for packaging containers
DK158598C (da) * 1988-07-07 1990-11-19 Pharma Vinci As Penicillinpraeparat til rektal administration
US5290933A (en) * 1989-04-26 1994-03-01 Smithkline & French Laboratories Limited Phenylpyrimidone derivatives
GB8909560D0 (en) * 1989-04-26 1989-06-14 Smith Kline French Lab Chemical compounds
GB8909558D0 (en) * 1989-04-26 1989-06-14 Smith Kline French Lab Chemical compounds
EA200500721A1 (ru) * 2002-11-28 2005-12-29 Шеринг Акциенгезельшафт Пиримидины, ингибирующие chk, pdk и акт, их получение и применение в качестве лекарственных средств
US10335374B2 (en) * 2014-12-04 2019-07-02 University System of Georgia, Valdosta State University Tablet composition for anti-tuberculosis antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634405A (en) * 1969-08-01 1972-01-11 Bristol Myers Co Synthetic penicillins
DE2450668A1 (de) * 1974-10-25 1976-04-29 Merck Patent Gmbh Ureidobenzylpenicilline und verfahren zu ihrer herstellung
FR2288521A1 (fr) * 1974-10-25 1976-05-21 Merck Patent Gmbh Nouvelles penicillines et procede pour leur preparation
NZ184434A (en) * 1976-06-30 1979-03-28 Dainippon Pharmaceutical Co Penicillins with a substituted p-hydroxy-benzyl side-chain, and injectable pharmaceutical compositions
US4038271A (en) * 1976-11-08 1977-07-26 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]-carbonyl]amino]acetylpenicillin derivatives

Also Published As

Publication number Publication date
AU4455979A (en) 1979-09-20
PT69279A (de) 1979-03-01
DE2961571D1 (en) 1982-02-11
ATA128279A (de) 1981-03-15
NZ189754A (en) 1984-10-19
HU180997B (en) 1983-05-30
AU522042B2 (en) 1982-05-13
EP0003814B1 (de) 1981-12-16
FI68237B (fi) 1985-04-30
USRE31926E (en) 1985-06-25
NO790628L (no) 1979-08-28
IE48323B1 (en) 1984-12-12
JPS54122291A (en) 1979-09-21
GR66677B (fi) 1981-04-08
AT364459B (de) 1981-10-27
JPS6058237B2 (ja) 1985-12-19
DK77479A (da) 1979-08-26
EP0003814A2 (de) 1979-09-05
FI790614A (fi) 1979-08-26
IL56731A0 (en) 1979-05-31
YU44979A (en) 1983-01-21
EP0003814A3 (en) 1979-10-17
IE790686L (en) 1979-08-25
CA1132539A (en) 1982-09-28
US4241056A (en) 1980-12-23
FI68237C (fi) 1985-08-12
ES477520A1 (es) 1979-06-01

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