IL56578A - Quinazoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Quinazoline derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL56578A
IL56578A IL56578A IL5657879A IL56578A IL 56578 A IL56578 A IL 56578A IL 56578 A IL56578 A IL 56578A IL 5657879 A IL5657879 A IL 5657879A IL 56578 A IL56578 A IL 56578A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
quinazoline derivatives
quinazoline
Prior art date
Application number
IL56578A
Other languages
English (en)
Other versions
IL56578A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL56578A0 publication Critical patent/IL56578A0/xx
Publication of IL56578A publication Critical patent/IL56578A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
IL56578A 1978-02-06 1979-02-02 Quinazoline derivatives,their preparation and pharmaceutical compositions containing them IL56578A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7803175A FR2421888A1 (fr) 1978-02-06 1978-02-06 Amides d'alkylene-diamines et leur application en therapeutique
FR7836819A FR2445323A2 (fr) 1978-02-06 1978-12-29 Amides d'alkylenediamines et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL56578A0 IL56578A0 (en) 1979-05-31
IL56578A true IL56578A (en) 1983-02-23

Family

ID=26220430

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56578A IL56578A (en) 1978-02-06 1979-02-02 Quinazoline derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US4315007A (xx)
JP (1) JPS6023114B2 (xx)
AT (1) AT365176B (xx)
AU (1) AU521524B2 (xx)
BE (1) BE873909A (xx)
CA (1) CA1102330A (xx)
CH (1) CH637122A5 (xx)
DE (1) DE2904445C2 (xx)
DK (1) DK159316C (xx)
ES (1) ES477457A1 (xx)
FI (1) FI66861C (xx)
FR (2) FR2421888A1 (xx)
GB (1) GB2013679B (xx)
GR (1) GR66846B (xx)
IE (1) IE47812B1 (xx)
IL (1) IL56578A (xx)
IT (1) IT1192347B (xx)
LU (1) LU80880A1 (xx)
NL (2) NL181482C (xx)
NO (1) NO151463C (xx)
NZ (1) NZ189553A (xx)
PT (1) PT69178A (xx)
SE (1) SE449360B (xx)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2466462A2 (fr) * 1978-02-06 1981-04-10 Synthelabo Derives d'alkylenediamines, leur preparation et leur application en therapeutique
DE3380093D1 (en) * 1982-09-30 1989-07-27 William John Louis 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
JPS6093016A (ja) * 1983-10-25 1985-05-24 Natl House Ind Co Ltd クランプ搬送装置
FR2577803B1 (fr) * 1985-02-26 1987-04-03 Synthelabo Compositions pharmaceutiques a base de nifedipine et d'alfuzosine
FR2570275B1 (fr) * 1984-09-14 1986-11-21 Synthelabo Compositions pharmaceutiques a base de diltiazem et d'alfusozine
FR2577804B1 (fr) * 1985-02-26 1987-03-27 Synthelabo Compositions pharmaceutiques a base de verapamil et d'alfuzosine
EP0189336A1 (fr) * 1985-01-18 1986-07-30 Synthelabo Compositions pharmaceutiques contenant un alpha-bloquant et un antagoniste du calcium
FR2582513B1 (fr) * 1985-05-28 1988-08-05 Synthelabo Compositions pharmaceutiques contenant de l'alfuzosine
LU86672A1 (fr) * 1986-11-19 1988-06-13 Oreal Composition pour induire et stimuler la croissance des cheveux et diminuer la chute a base de derives d'alkylene diamino quinazoline
YU70890A (en) * 1989-04-21 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for obtaining quinazoline derivatives
IL101243A (en) * 1991-03-20 1999-12-22 Merck & Co Inc Pharmaceutical preparations for the treatment of benign prostatic hyperplasia containing steroid history
FR2694495B1 (fr) * 1992-08-05 1994-09-23 Synthelabo Préparation pharmaceutique transdermique contenant de l'alfuzosine.
JPH07206857A (ja) * 1993-12-28 1995-08-08 Synthelabo Sa アルフゾシン塩酸塩の二水和物
FR2717388B1 (fr) * 1994-03-21 1996-11-22 Synthelabo Formes galéniques à libération prolongée du chlorhydrate d'alfuzosine.
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides
EP1891954A3 (en) 1998-09-30 2009-01-14 Takeda Pharmaceutical Company Limited Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder
WO2001068615A1 (en) * 2000-03-13 2001-09-20 Chemrx Advanced Technologies, Inc. Quinazoline synthesis
US20020065286A1 (en) * 2000-08-21 2002-05-30 Davies Michael John Treatment of wounds
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
GB0130219D0 (en) * 2001-12-18 2002-02-06 Pfizer Ltd Compounds for the treatment of sexual dysfunction
US20030229001A1 (en) * 2002-01-31 2003-12-11 Pfizer Inc. Treatment of male sexual dysfunction
GB0219961D0 (en) 2002-08-28 2002-10-02 Pfizer Ltd Oxytocin inhibitors
US7323462B2 (en) * 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
PA8597401A1 (es) * 2003-03-14 2005-05-24 Pfizer Derivados del acido 3-(1-[3-(1,3-benzotiazol-6-il) propilcarbamoil] cicloalquil) propanoico como inhibidores de nep
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
US20050065158A1 (en) * 2003-07-16 2005-03-24 Pfizer Inc. Treatment of sexual dysfunction
US7291640B2 (en) * 2003-09-22 2007-11-06 Pfizer Inc. Substituted triazole derivatives as oxytocin antagonists
US20050267096A1 (en) * 2004-05-26 2005-12-01 Pfizer Inc New indazole and indolone derivatives and their use pharmaceuticals
US20050288270A1 (en) * 2004-05-27 2005-12-29 Pfizer Inc New aminopyridine derivatives and their use as pharmaceuticals
ES2305848T3 (es) * 2004-09-16 2008-11-01 Hetero Drugs Limited Base cristalina de alfuzosina.
JP2008533193A (ja) * 2005-03-21 2008-08-21 ファイザー・リミテッド オキシトシン拮抗薬としての置換トリアゾール誘導体
WO2006100557A1 (en) * 2005-03-21 2006-09-28 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
WO2007017752A1 (en) * 2005-08-10 2007-02-15 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
US20070066824A1 (en) * 2005-09-22 2007-03-22 Anumula Raghupathi R Preparation of alfuzosin
US20070105880A1 (en) * 2005-11-08 2007-05-10 Torrent Pharmaceuticals Limited Process for the preparation of alfuzosin
US20090069562A1 (en) * 2005-12-26 2009-03-12 Joseph Prabahar Koilpillai Process for the preparation of alfuzosin
CN101190890B (zh) 2006-11-30 2011-04-27 江苏豪森药业股份有限公司 5-[(2r)-[2-[2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基]氨基]丙基]-2-甲氧基苯磺酰胺
WO2008073388A2 (en) * 2006-12-11 2008-06-19 Mutual Pharmaceutical Company, Inc. Alfuzosin formulations, methods of making and methods of use
US20100092556A1 (en) * 2006-12-11 2010-04-15 Kristin Arnold Alfuzosin formulations, methods of making, and methods of use
WO2008152514A2 (en) 2007-05-04 2008-12-18 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
WO2009001369A1 (en) * 2007-06-22 2008-12-31 Alembic Limited An improved process for the preparation of alfuzosin hydrochloride
WO2009007987A1 (en) * 2007-07-11 2009-01-15 Alembic Limited An improved process for the preparation of alfuzosin and its novel polymorph
US8716476B2 (en) * 2007-08-02 2014-05-06 Cipla Limited Process for the preparation of alfuzosin hydrochloride
US20090076043A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched alfuzosin
US20100183717A1 (en) * 2009-01-16 2010-07-22 Kristin Arnold Controlled-release formulations
CN107998090A (zh) * 2017-12-30 2018-05-08 威海贯标信息科技有限公司 一种阿夫唑嗪片组合物
CN113801069B (zh) * 2020-06-15 2024-03-15 鲁南制药集团股份有限公司 一种盐酸阿夫唑嗪中间体化合物
CN114573569B (zh) * 2022-03-30 2023-07-04 邦恩泰(山东)生物医药科技集团股份有限公司 一种异喹啉类化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
FR2362630A1 (fr) * 1976-08-24 1978-03-24 Synthelabo Derives d'alkylenediamines
FR2350101A1 (fr) * 1976-05-07 1977-12-02 Synthelabo Nouvelles guanidines cyclisees
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf
FR2389613A2 (en) * 1977-05-05 1978-12-01 Synthelabo Antihypertensive 4-amino-6,7-di:methoxy-quinazolyl alkylene di:amine - prepd. from a 2-halo-quinazoline and an alkylene di:amine

Also Published As

Publication number Publication date
GB2013679B (en) 1982-09-02
AU4389579A (en) 1979-08-16
NO790358L (no) 1979-08-07
FR2445323B2 (xx) 1981-11-27
DE2904445C2 (de) 1986-10-30
SE449360B (sv) 1987-04-27
DK46079A (da) 1979-08-07
BE873909A (fr) 1979-08-02
IT1192347B (it) 1988-03-31
DK159316C (da) 1991-03-04
ES477457A1 (es) 1979-10-16
JPS54117487A (en) 1979-09-12
ATA84279A (de) 1981-05-15
IE47812B1 (en) 1984-06-27
NL930043I2 (nl) 1993-11-16
NZ189553A (en) 1981-05-01
FR2421888A1 (fr) 1979-11-02
IL56578A0 (en) 1979-05-31
AT365176B (de) 1981-12-28
FI66861B (fi) 1984-08-31
CH637122A5 (fr) 1983-07-15
FR2421888B1 (xx) 1980-09-26
SE7900987L (sv) 1979-08-07
NL7900917A (nl) 1979-08-08
NL181482B (nl) 1987-04-01
AU521524B2 (en) 1982-04-08
FI790369A (fi) 1979-08-07
PT69178A (fr) 1979-03-01
GR66846B (xx) 1981-05-05
FI66861C (fi) 1984-12-10
CA1102330A (en) 1981-06-02
NL930043I1 (nl) 1993-08-02
DK159316B (da) 1990-10-01
IT7919908A0 (it) 1979-02-05
NO151463B (no) 1985-01-02
US4315007A (en) 1982-02-09
GB2013679A (en) 1979-08-15
NO151463C (no) 1985-04-17
FR2445323A2 (fr) 1980-07-25
IE790210L (en) 1979-08-06
JPS6023114B2 (ja) 1985-06-05
NL181482C (nl) 1987-09-01
DE2904445A1 (de) 1979-08-16
LU80880A1 (fr) 1980-09-24

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Legal Events

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