IL56265A - Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor - Google Patents

Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor

Info

Publication number
IL56265A
IL56265A IL7856265A IL5626578A IL56265A IL 56265 A IL56265 A IL 56265A IL 7856265 A IL7856265 A IL 7856265A IL 5626578 A IL5626578 A IL 5626578A IL 56265 A IL56265 A IL 56265A
Authority
IL
Israel
Prior art keywords
guanidine derivatives
novel intermediate
intermediate therefor
preparing
methylthio
Prior art date
Application number
IL7856265A
Other languages
English (en)
Other versions
IL56265A0 (en
Original Assignee
Om Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1612677A external-priority patent/CH626353A5/fr
Priority claimed from CH1247778A external-priority patent/CH636348A5/fr
Application filed by Om Lab Sa filed Critical Om Lab Sa
Publication of IL56265A0 publication Critical patent/IL56265A0/xx
Publication of IL56265A publication Critical patent/IL56265A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/20—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carbonic acid, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL7856265A 1977-12-28 1978-12-20 Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor IL56265A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1612677A CH626353A5 (en) 1977-12-28 1977-12-28 Process for the preparation of a guanidine
CH1247778A CH636348A5 (en) 1978-12-07 1978-12-07 Process for the preparation of guanidine derivatives

Publications (2)

Publication Number Publication Date
IL56265A0 IL56265A0 (en) 1979-03-12
IL56265A true IL56265A (en) 1982-08-31

Family

ID=25710349

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7856265A IL56265A (en) 1977-12-28 1978-12-20 Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor

Country Status (12)

Country Link
JP (2) JPS5827792B2 (ro)
CS (1) CS208770B2 (ro)
DE (1) DE2855836A1 (ro)
ES (1) ES476707A1 (ro)
FI (1) FI74954C (ro)
IL (1) IL56265A (ro)
IT (1) IT1102776B (ro)
NL (1) NL184832C (ro)
PL (1) PL115042B1 (ro)
RO (1) RO76087A (ro)
SU (1) SU1077570A3 (ro)
YU (1) YU41138B (ro)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
NO784350L (no) * 1977-12-30 1979-07-03 Crc Ricerca Chim Fremgangsmaate til alkylering av 4(5)-merkaptometyl-imidazoler med aziridinderivater
YU40332B (en) * 1978-04-26 1985-12-31 Lek Tovarna Farmacevtskih Process for preparing n-cyano-n'-methyl-n''-((2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-guanidine
LU81178A1 (de) * 1978-05-12 1979-09-10 Crc Ricerca Chim Neue thiolderivate des imidazols
US4222845A (en) * 1978-12-13 1980-09-16 Gulf Oil Corporation Integrated coal liquefaction-gasification-naphtha reforming process
WO1980001694A1 (en) * 1979-02-14 1980-08-21 Rech Syntheses Organ Imino-alkyl and amino-nitryl cyano-guanidinze
CH642068A5 (fr) * 1979-03-14 1984-03-30 Rech Syntheses Organ Cyano-urees et cyano-thiourees therapeutiquement actives.
PT72320B (en) 1980-01-08 1982-07-23 Glaxo Group Ltd Process for preparation of a furan derivative
YU41689B (en) * 1980-01-14 1987-12-31 Lek Tovarna Farmacevtskih Process for preparing imidazole derivatives
DE3014353A1 (de) * 1980-04-15 1982-01-21 Bayer Ag, 5090 Leverkusen Trisubstituierte cyanguanidine, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
JPS5888366A (ja) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk グアニジン誘導体の製造法
JPS59130273A (ja) * 1983-01-14 1984-07-26 Tokawa Tetsuo イミダゾ−ル系化合物の製造法
JPS6170789U (ro) * 1984-10-16 1986-05-14
GB8502446D0 (en) * 1985-01-31 1985-03-06 Smith Kline French Lab Preparing aziridine derivative
YU45030B (en) * 1987-01-23 1991-06-30 Lek Tovarna Farmacevtskih Process for preparing crystalline cimetidine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE36050B1 (en) * 1971-03-09 1976-08-04 Smith Kline French Lab Ureas thioureas and guanidines
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
JPS5817511B2 (ja) * 1975-10-03 1983-04-07 積水化学工業株式会社 セツチヤクザイソセイブツ
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
JPS5440547A (en) * 1977-09-07 1979-03-30 Seikosha Kk Device for adjusting output frequency of frequency divider
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
JPS5742068A (en) * 1980-08-27 1982-03-09 Ricoh Co Ltd Solvent recovering device for wet type electronic copying machine
JPS6011994B2 (ja) * 1981-08-10 1985-03-29 池田 博美 ガソリンエンジン用液体燃料
JPS5888366A (ja) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk グアニジン誘導体の製造法

Also Published As

Publication number Publication date
NL7812600A (nl) 1979-07-02
PL212223A1 (pl) 1979-08-27
IT7831392A0 (it) 1978-12-28
JPS6140667B2 (ro) 1986-09-10
FI74954B (fi) 1987-12-31
PL115042B1 (en) 1981-03-31
NL184832C (nl) 1989-11-16
ES476707A1 (es) 1979-06-01
DE2855836A1 (de) 1979-07-12
FI74954C (fi) 1988-04-11
YU41138B (en) 1986-12-31
JPS5827792B2 (ja) 1983-06-11
FI783990A (fi) 1979-06-29
DE2855836C2 (ro) 1989-09-28
RO76087A (ro) 1981-02-28
SU1077570A3 (ru) 1984-02-29
JPS5962572A (ja) 1984-04-10
CS208770B2 (en) 1981-09-15
IL56265A0 (en) 1979-03-12
JPS54130566A (en) 1979-10-09
IT1102776B (it) 1985-10-07
YU308478A (en) 1983-01-21

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