IL53978A - Non-adhesive ionene quaternary polymer bile-acid sequestrant absorbate compositions and process for their preparation - Google Patents

Non-adhesive ionene quaternary polymer bile-acid sequestrant absorbate compositions and process for their preparation

Info

Publication number
IL53978A
IL53978A IL53978A IL5397878A IL53978A IL 53978 A IL53978 A IL 53978A IL 53978 A IL53978 A IL 53978A IL 5397878 A IL5397878 A IL 5397878A IL 53978 A IL53978 A IL 53978A
Authority
IL
Israel
Prior art keywords
ionene
absorbate
compositions
adhesive
preparation
Prior art date
Application number
IL53978A
Other languages
English (en)
Other versions
IL53978A0 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL53978A0 publication Critical patent/IL53978A0/xx
Publication of IL53978A publication Critical patent/IL53978A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
IL53978A 1977-02-17 1978-02-06 Non-adhesive ionene quaternary polymer bile-acid sequestrant absorbate compositions and process for their preparation IL53978A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76949177A 1977-02-17 1977-02-17

Publications (2)

Publication Number Publication Date
IL53978A0 IL53978A0 (en) 1978-04-30
IL53978A true IL53978A (en) 1981-03-31

Family

ID=25085598

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53978A IL53978A (en) 1977-02-17 1978-02-06 Non-adhesive ionene quaternary polymer bile-acid sequestrant absorbate compositions and process for their preparation

Country Status (26)

Country Link
JP (1) JPS53102958A (nl)
AT (1) AT363173B (nl)
AU (1) AU518127B2 (nl)
BE (1) BE863930A (nl)
CA (1) CA1109395A (nl)
CH (1) CH636012A5 (nl)
DE (1) DE2806707A1 (nl)
DK (1) DK46578A (nl)
ES (1) ES466892A1 (nl)
FI (1) FI67483C (nl)
FR (1) FR2381079A1 (nl)
GB (1) GB1567294A (nl)
GR (1) GR66100B (nl)
HU (1) HU177685B (nl)
IE (1) IE46408B1 (nl)
IL (1) IL53978A (nl)
IT (1) IT7848013A0 (nl)
LU (1) LU79071A1 (nl)
NL (1) NL7801240A (nl)
NO (1) NO148838C (nl)
NZ (1) NZ186399A (nl)
PH (1) PH15263A (nl)
PL (1) PL122299B1 (nl)
PT (1) PT67663B (nl)
SE (1) SE433170B (nl)
ZA (1) ZA78913B (nl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5709880A (en) * 1995-07-10 1998-01-20 Buckman Laboratories International, Inc. Method of making tabletized ionene polymers
EP0778027A3 (de) 1995-12-04 1998-04-01 Helmut Univ.-Prof. Dr. Wachter Verwendung von Kieselerde zur Herstellung von Arzneimitteln
JP4010585B2 (ja) * 1996-10-15 2007-11-21 久光製薬株式会社 陰イオン交換樹脂を含有する錠剤
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol

Also Published As

Publication number Publication date
AU518127B2 (en) 1981-09-17
CA1109395A (en) 1981-09-22
IE46408B1 (en) 1983-06-01
IT7848013A0 (it) 1978-02-10
FI780296A (fi) 1978-08-18
NO780367L (no) 1978-08-18
ATA87978A (de) 1980-12-15
ZA78913B (en) 1979-09-26
ES466892A1 (es) 1979-08-16
HU177685B (en) 1981-12-28
IE780332L (en) 1978-08-17
IL53978A0 (en) 1978-04-30
PL204642A1 (pl) 1979-06-04
FR2381079A1 (fr) 1978-09-15
SE7801242L (sv) 1978-08-18
AT363173B (de) 1981-07-10
GB1567294A (en) 1980-05-14
PT67663A (en) 1978-03-01
NL7801240A (nl) 1978-08-21
SE433170B (sv) 1984-05-14
DK46578A (da) 1978-08-18
FI67483B (fi) 1984-12-31
CH636012A5 (en) 1983-05-13
GR66100B (nl) 1981-01-16
PT67663B (en) 1980-03-03
BE863930A (fr) 1978-08-14
FR2381079B1 (nl) 1981-09-11
FI67483C (fi) 1985-04-10
NZ186399A (en) 1980-11-28
PL122299B1 (en) 1982-07-31
PH15263A (en) 1982-11-02
NO148838B (no) 1983-09-19
NO148838C (no) 1983-12-28
LU79071A1 (fr) 1978-09-28
JPS53102958A (en) 1978-09-07
AU3309978A (en) 1979-08-16
DE2806707A1 (de) 1978-08-24

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