IL53594A - Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them - Google Patents

Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL53594A
IL53594A IL53594A IL5359477A IL53594A IL 53594 A IL53594 A IL 53594A IL 53594 A IL53594 A IL 53594A IL 5359477 A IL5359477 A IL 5359477A IL 53594 A IL53594 A IL 53594A
Authority
IL
Israel
Prior art keywords
cells
release
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL53594A
Other languages
English (en)
Original Assignee
Kernforschungsanlage Juelich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsanlage Juelich filed Critical Kernforschungsanlage Juelich
Publication of IL53594A publication Critical patent/IL53594A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL53594A 1976-12-09 1977-12-13 Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them IL53594A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2655801A DE2655801C2 (de) 1976-12-09 1976-12-09 Injizierbare Suspension von Membranvesikeln aus Erythrozyten und Verfahren zur Herstellung der Suspension

Publications (1)

Publication Number Publication Date
IL53594A true IL53594A (en) 1981-06-29

Family

ID=5995087

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53594A IL53594A (en) 1976-12-09 1977-12-13 Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US4224313A (de)
JP (1) JPS5372890A (de)
CH (1) CH632927A5 (de)
DE (1) DE2655801C2 (de)
FR (1) FR2373289A1 (de)
GB (1) GB1560165A (de)
IL (1) IL53594A (de)
SE (1) SE445294B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2656746C2 (de) * 1976-12-15 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verwendung von beladenen Erythrozyten
US4489162A (en) * 1981-12-21 1984-12-18 American Hospital Supply Corporation Fresh blood (unfixed) hematology control
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
US4478824A (en) * 1983-08-08 1984-10-23 Franco Robert S Method for altering red blood cell function and survival
US4610241A (en) * 1984-07-03 1986-09-09 Gordon Robert T Atherosclerosis treatment method
US4931276A (en) * 1987-10-30 1990-06-05 Franco Robert S Method for introducing desired agents into red blood cells
DE3812816A1 (de) * 1988-04-16 1989-11-02 Lawaczeck Ruediger Dipl Phys P Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung
US4935223A (en) * 1988-08-04 1990-06-19 Board Of Regents, The University Of Texas System Labeled cells for use in imaging
US5116615A (en) * 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
DK0456724T3 (da) 1989-01-27 1995-10-02 Immunolytics Inc Præparat og fremgangsmåde til behandling af benign prostatisk hypertrofi
US5443813A (en) * 1991-06-06 1995-08-22 Associated Universities, Inc. Loading and conjugating cavity biostructures
WO1993018397A1 (en) * 1992-03-02 1993-09-16 Streck Laboratories, Inc. Reference control for use with manual and flow cytometric reticulocyte counting devices
US20020111461A1 (en) * 1999-05-21 2002-08-15 Todd C. Somers Low molecular weight peptidomimetic growth hormone secretagogues
US5798337A (en) * 1994-11-16 1998-08-25 Genentech, Inc. Low molecular weight peptidomimetic growth hormone secretagogues
DE69732225T2 (de) * 1997-05-05 2005-06-23 Dideco S.R.L., Mirandola Verfahren zur Verkapselung von biologisch aktiven Stoffen in Erythrocyten und Gerät dafür
GB9917416D0 (de) * 1999-07-23 1999-09-22 Univ Ulster
DE60026313D1 (de) 1999-07-23 2006-04-27 Uutech Ltd Sensibilisierung von roten blutkörperchen gegenüber ultraschall durch einwirkung eines elektrischen feldes
US20040071664A1 (en) * 1999-07-23 2004-04-15 Gendel Limited Delivery of an agent
GB0002856D0 (en) * 2000-02-08 2000-03-29 Gendel Limited Ultrasound sensitisation
GB0025147D0 (en) * 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
BRPI0414970A2 (pt) * 2003-06-24 2012-12-11 Baxter Int método para transporte de drogas ao cérebro
US8986736B2 (en) * 2003-06-24 2015-03-24 Baxter International Inc. Method for delivering particulate drugs to tissues
AU2005209243A1 (en) * 2004-01-29 2005-08-11 Baxter Healthcare S.A. Nanosuspensions of anti-retroviral agents for increased central nervous system delivery
RU2006144851A (ru) * 2004-06-15 2008-06-20 Бакстер Интернэшнл Инк. (Us) Применение терапевтических средств ex-vivo в виде твердых микрочастиц
BRPI0909780B1 (pt) 2008-03-05 2022-05-03 Baxter International Inc Suspensão contendo uma partícula com superfície modificada, composição farmacêutica compreendendo a referida suspensão, método para aprimorar a absorção celular de um agente ativo, uso de partículas com superfície modificada, e método de preparação de uma partícula com superfície modificada
DE102008029172A1 (de) 2008-06-19 2009-12-24 Kenndoff, Jochen, Dr. Verfahren zum Schutz von insbesondere verletzten oder gestressten Hautbereichen einer Zitze während des Melkvorgangs
US10952965B2 (en) * 2009-05-15 2021-03-23 Baxter International Inc. Compositions and methods for drug delivery
IT1399590B1 (it) 2010-04-26 2013-04-26 Erydel Spa Apparato e kit per incapsulare almeno un composto ad uso terapeutico e/o diagnostico all'interno di eritrociti
ITBO20100256A1 (it) * 2010-04-26 2011-10-27 Erydel Spa Metodo per incapsulare almeno un composto ad uso terapeutico e/o diagnostico all'interno di eritrociti
FR3005420B1 (fr) * 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887698A (en) * 1973-03-12 1975-06-03 Univ Leland Stanford Junior Sacs with epitopic sites on walls enclosing stable free radicals
DE2326191B2 (de) 1973-05-23 1978-03-30 Hutschenreuther Ag, 8672 Selb Verfahren zum Herstellen eines Reliefdekors auf keramischen Erzeugnissen
DE2326224C3 (de) 1973-05-23 1975-11-13 Kernforschungsanlage Juelich Gmbh, 5170 Juelich Verfahren zum Abtrenne», von durch chemische oder physikalisch^ Eigenschaften ausgezeichneten ionisierten Stoffen aus einer wäßrigen Lösung
DE2326161C2 (de) * 1973-05-23 1986-07-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zum Aufbau oder zum Abbau von durch chemische Eigenschaften ausgezeichneten, in einer wäßrigen Lösung enthaltenen Stoffen
GB1481480A (en) * 1974-02-02 1977-07-27 Kernforschungsanlage Juelich Process and apparatus for increasing the permeability of the membrane of cells of organisms
DE2656746C2 (de) * 1976-12-15 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verwendung von beladenen Erythrozyten

Also Published As

Publication number Publication date
CH632927A5 (de) 1982-11-15
US4224313A (en) 1980-09-23
SE445294B (sv) 1986-06-16
FR2373289A1 (fr) 1978-07-07
JPS5372890A (en) 1978-06-28
GB1560165A (en) 1980-01-30
DE2655801C2 (de) 1986-06-26
FR2373289B1 (de) 1981-05-29
DE2655801A1 (de) 1978-06-22
SE7713944L (sv) 1978-06-10

Similar Documents

Publication Publication Date Title
IL53594A (en) Biological cells comprising pharmaceutically active substances and additives controlling their release from the cells,their preparation and pharmaceutical compositions containing them
DE2962051D1 (en) Benzimidazoles, their preparation and pharmaceutical compositions containing them
IL59288A (en) 1-aryl-2-acylamido-3-fluoro-1-propanols,their preparation and pharmaceutical compositions containing them
IL57672A (en) Phenethanolamines,their preparation and pharmaceutical compositions containing the same
IL56992A (en) N-heterocyclyl-4-piperidinamines,their preparation and pharmaceutical compositions containing them
IL53596A (en) Biological cells externally modified for controlled release,in the spleen and/or liver,of pharmaceutically active substances comprised therein,their preparation and pharmaceutical compositions containing them
IL59150A0 (en) N-benzyl-imidazoles,their preparation and pharmaceutical compostions containing them
IL60800A (en) 5-substituted-2,3-diarylthiophenes,their preparation and pharmaceutical compositions containing them
IL60678A0 (en) 3-amino-syndone-imines, their preparation and pharmaceutical compositions containing them
IL60918A (en) 6-pyridazinones,their preparation and pharmaceutical compositions containing them
IL59558A (en) 9-aminoalkylfluorenes,their preparation and pharmaceutical compositions comprising them
DE2965287D1 (en) Bis-imidazoles, their preparation and pharmaceutical compositions containing them
DE3068074D1 (en) Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them
DE3070184D1 (en) Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them
DE2966364D1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them
IL60307A0 (en) Alkoxybenzylpyridopyrimidines,their preparation and pharmaceutical compositions containing them
DE3067790D1 (en) Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them
IL60700A0 (en) 25-halocholest-5-ene-2 ,22-diols and esters thereof and pharmaceutical compositions containing them
IL56686A0 (en) Acylaminoalkyl-syanoguanidines,their preparation and pharmaceutical compositions containing them
IL57667A (en) 2-azaergolines and 2-aza-8-ergolines,their preparation and pharmaceutical compositions containing them
IL53552A (en) 1-piperazinopropanol esters,their preparation and pharmaceutical compositions containing them
IL53674A (en) 3-(4-phenylpiperazinyl or 4-phenylpiperidyl) o-propyloximes,their preparation and pharmaceutical compositions comprising them
IL52952A (en) Hydroxymethyl-pyridine esters,their preparation and pharmaceutical compositions containing them
GB2024818B (en) Phenathrenederivatives, their preparation and pharmaceutical compositions containing them
IL54001A0 (en) 2,4-dichlorophenyl-imidazolyl-ethan-ones and -ols, their preparation and pharmaceutical compositions containing the