IL53506A - Spiro-3,5"-oxazolidine-2",4"-dione derivatives of 3-descarbo-methoxy-3-deshydroxy vinca alkaloids,pharmaceutical compositions containing them and vinca alkaloid 3-carbamates as intermediates therefor - Google Patents
Spiro-3,5"-oxazolidine-2",4"-dione derivatives of 3-descarbo-methoxy-3-deshydroxy vinca alkaloids,pharmaceutical compositions containing them and vinca alkaloid 3-carbamates as intermediates thereforInfo
- Publication number
- IL53506A IL53506A IL53506A IL5350677A IL53506A IL 53506 A IL53506 A IL 53506A IL 53506 A IL53506 A IL 53506A IL 5350677 A IL5350677 A IL 5350677A IL 53506 A IL53506 A IL 53506A
- Authority
- IL
- Israel
- Prior art keywords
- vinca
- descarbo
- deshydroxy
- oxazolidine
- carbamates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/747,575 US4096148A (en) | 1976-12-06 | 1976-12-06 | Oxazolidinedione derivatives of Vinca alkaloids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL53506A0 IL53506A0 (en) | 1978-03-10 |
| IL53506A true IL53506A (en) | 1981-09-13 |
Family
ID=25005690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL53506A IL53506A (en) | 1976-12-06 | 1977-12-01 | Spiro-3,5"-oxazolidine-2",4"-dione derivatives of 3-descarbo-methoxy-3-deshydroxy vinca alkaloids,pharmaceutical compositions containing them and vinca alkaloid 3-carbamates as intermediates therefor |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4096148A (da) |
| JP (1) | JPS5371100A (da) |
| AR (1) | AR218467A1 (da) |
| AT (2) | AT361638B (da) |
| AU (1) | AU513936B2 (da) |
| BE (1) | BE861417A (da) |
| BG (1) | BG33436A3 (da) |
| CA (2) | CA1082180A (da) |
| CH (2) | CH634076A5 (da) |
| CS (2) | CS195343B2 (da) |
| DD (2) | DD134227A5 (da) |
| DE (1) | DE2753791A1 (da) |
| DK (2) | DK145001C (da) |
| ES (2) | ES464765A1 (da) |
| FR (1) | FR2372839A1 (da) |
| GB (1) | GB1590649A (da) |
| GR (2) | GR67244B (da) |
| HK (1) | HK57281A (da) |
| HU (2) | HU180724B (da) |
| IE (1) | IE46105B1 (da) |
| IL (1) | IL53506A (da) |
| MX (1) | MX4326E (da) |
| MY (1) | MY8200176A (da) |
| NL (1) | NL7713336A (da) |
| NZ (1) | NZ185818A (da) |
| PL (2) | PL110671B1 (da) |
| PT (2) | PT67343B (da) |
| RO (2) | RO74137A (da) |
| SE (2) | SE435930B (da) |
| SU (2) | SU843753A3 (da) |
| ZA (1) | ZA777237B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181874B (en) * | 1977-08-08 | 1983-11-28 | Lilly Co Eli | Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine |
| US4357334A (en) * | 1980-03-20 | 1982-11-02 | Eli Lilly And Company | Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms |
| US4362664A (en) * | 1980-12-29 | 1982-12-07 | Eli Lilly And Company | Vinblastine oxazolidinedione disulfides and related compounds |
| EP0124502B1 (fr) * | 1983-04-29 | 1991-06-12 | OMNICHEM Société anonyme | Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués |
| HUT76925A (hu) * | 1995-04-04 | 1998-01-28 | MTA Enzimológiai Intézet | Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények |
| EP1229934B1 (en) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL265085A (da) * | 1960-05-24 | |||
| HU165986B (da) * | 1973-02-16 | 1974-12-28 | ||
| AR204004A1 (es) * | 1973-04-02 | 1975-11-12 | Lilly Co Eli | Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina |
| US4012390A (en) * | 1974-10-16 | 1977-03-15 | Eli Lilly And Company | Vinblastinoic acid |
-
1976
- 1976-12-06 US US05/747,575 patent/US4096148A/en not_active Expired - Lifetime
-
1977
- 1977-11-30 CA CA292,101A patent/CA1082180A/en not_active Expired
- 1977-11-30 SE SE7713587A patent/SE435930B/sv not_active IP Right Cessation
- 1977-11-30 GB GB49906/77A patent/GB1590649A/en not_active Expired
- 1977-11-30 CS CS777939A patent/CS195343B2/cs unknown
- 1977-11-30 GR GR54898A patent/GR67244B/el unknown
- 1977-11-30 SE SE7713586A patent/SE436036B/sv not_active IP Right Cessation
- 1977-11-30 CA CA292,072A patent/CA1103664A/en not_active Expired
- 1977-11-30 RO RO7792262A patent/RO74137A/ro unknown
- 1977-11-30 RO RO7792261A patent/RO75391A/ro unknown
- 1977-11-30 PT PT67343A patent/PT67343B/pt unknown
- 1977-11-30 PT PT67342A patent/PT67342B/pt unknown
- 1977-11-30 GR GR54897A patent/GR67243B/el unknown
- 1977-11-30 CS CS777940A patent/CS195344B2/cs unknown
- 1977-11-30 NZ NZ185818A patent/NZ185818A/xx unknown
- 1977-12-01 IL IL53506A patent/IL53506A/xx unknown
- 1977-12-01 NL NL7713336A patent/NL7713336A/xx not_active Application Discontinuation
- 1977-12-02 BE BE1008557A patent/BE861417A/xx not_active IP Right Cessation
- 1977-12-02 BG BG7737936A patent/BG33436A3/xx unknown
- 1977-12-02 FR FR7736437A patent/FR2372839A1/fr active Granted
- 1977-12-02 JP JP14561377A patent/JPS5371100A/ja active Granted
- 1977-12-02 DE DE19772753791 patent/DE2753791A1/de active Granted
- 1977-12-05 PL PL1977202659A patent/PL110671B1/pl unknown
- 1977-12-05 CH CH1486177A patent/CH634076A5/de not_active IP Right Cessation
- 1977-12-05 CH CH1486277A patent/CH632516A5/de not_active IP Right Cessation
- 1977-12-05 MX MX776608U patent/MX4326E/es unknown
- 1977-12-05 ES ES464765A patent/ES464765A1/es not_active Expired
- 1977-12-05 ZA ZA00777237A patent/ZA777237B/xx unknown
- 1977-12-05 AT AT868777A patent/AT361638B/de not_active IP Right Cessation
- 1977-12-05 DK DK541077A patent/DK145001C/da not_active IP Right Cessation
- 1977-12-05 PL PL1977202660A patent/PL106522B1/pl unknown
- 1977-12-05 ES ES464764A patent/ES464764A1/es not_active Expired
- 1977-12-05 DK DK541177A patent/DK144916C/da not_active IP Right Cessation
- 1977-12-05 HU HU77EI771A patent/HU180724B/hu not_active IP Right Cessation
- 1977-12-05 IE IE2469/77A patent/IE46105B1/en unknown
- 1977-12-05 AU AU31230/77A patent/AU513936B2/en not_active Expired
- 1977-12-05 SU SU772549952A patent/SU843753A3/ru active
- 1977-12-05 HU HU77EI7723A patent/HU180725B/hu not_active IP Right Cessation
- 1977-12-05 AT AT868877A patent/AT353987B/de not_active IP Right Cessation
- 1977-12-05 SU SU772549000A patent/SU865127A3/ru active
- 1977-12-06 DD DD77202423A patent/DD134227A5/xx unknown
- 1977-12-06 DD DD77202424A patent/DD134228A5/xx unknown
- 1977-12-06 AR AR270267A patent/AR218467A1/es active
-
1981
- 1981-11-19 HK HK572/81A patent/HK57281A/xx unknown
-
1982
- 1982-12-30 MY MY176/82A patent/MY8200176A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU536181B2 (en) | Derivatives of camptothecin | |
| IL53419A0 (en) | Pharmaceutical compositions containing certain ergot peptide alkaloids | |
| PH15719A (en) | Aminoalkylbenzoic derivatives,pharmaceutical composition and method of use | |
| IL52280A0 (en) | New derivatives of penicillanic acid their preparation and pharmaceutical compositions containing them | |
| NZ182190A (en) | Clavulanic acid derivatives and pharmaceutical compositions | |
| PH14555A (en) | Alkoxypyridyl compound derivatives and pharmaceutical composition useful as histamine h2 antagonists | |
| PH19005A (en) | Penicillanic acid derivatives,pharmaceutical compositions containing the same and method of use thereof | |
| IL51339A0 (en) | New beta-lactam containing compounds their preparation and pharmaceutical compositions containing them | |
| IL53506A (en) | Spiro-3,5"-oxazolidine-2",4"-dione derivatives of 3-descarbo-methoxy-3-deshydroxy vinca alkaloids,pharmaceutical compositions containing them and vinca alkaloid 3-carbamates as intermediates therefor | |
| IL51267A0 (en) | Novel clavulanic acid derivatives their preparation and pharmaceutical compositions containing them | |
| NZ184102A (en) | Derivatives of benzenesulphonylurea,and pharmaceutical compositions | |
| AU514324B2 (en) | Preparation of alkaloids ofthe leurosine type | |
| AU511055B2 (en) | Amide derivatives of'VLB, Leuosidine, Leuocristine and related dimeric alkaloids | |
| NZ189087A (en) | Amino derivatives of tetracyclo (4,3,0,0,0)nonane and pharmaceutical compositions | |
| NZ187285A (en) | Azacyclic derivatives of 6-amino-penam compounds and pharmaceutical compositions | |
| IL52087A0 (en) | Novel benzo(c)quinoline derivatives and pharmaceutical compositions containing them | |
| IL67263A0 (en) | Novel azino rifamycins,their preparation and pharmaceutical composition containing them | |
| IL52378A0 (en) | Novel bicyclic and tricyclic carbostyril derivatives their preparation and pharmaceutical compositions containing them | |
| IL49668A (en) | Stable solutions of hydrogenated ergopeptide alkaloids,their preparation and pharmaceutical composition comprising them | |
| NZ185267A (en) | Derivatives of 1-amino-2hydroxy-3-heterocycloxy-propanes, and pharmaceutical compositions containing them | |
| DE2861607D1 (en) | Derivatives of clavulanic acid and pharmaceutical compositions containing them | |
| DE2966195D1 (en) | 5-oxo-5h-hexahydrofuro(3,2-b)pyrrole derivatives, their preparation, intermediates, and pharmaceutical compositions containing said derivatives | |
| JPS5686116A (en) | Stable solution of hydrogenated ergot alkaloids | |
| PH18155A (en) | Ergot peptide alkaloid derivatives and pharmaceutical compositions containing them | |
| PH12050A (en) | Benzisothiazoline-1,1-dioxide derivatives,compositions and methods of use thereof |