IL51530A - Imidazolyl (thiazolyl) methyl-thioalkyl amidinoformic (sulfinic) acid derivatives,process for their preparation and pharmalceutical compositions containing them - Google Patents

Imidazolyl (thiazolyl) methyl-thioalkyl amidinoformic (sulfinic) acid derivatives,process for their preparation and pharmalceutical compositions containing them

Info

Publication number
IL51530A
IL51530A IL51530A IL5153077A IL51530A IL 51530 A IL51530 A IL 51530A IL 51530 A IL51530 A IL 51530A IL 5153077 A IL5153077 A IL 5153077A IL 51530 A IL51530 A IL 51530A
Authority
IL
Israel
Prior art keywords
pharmalceutical
amidinoformic
sulfinic
thioalkyl
thiazolyl
Prior art date
Application number
IL51530A
Other languages
English (en)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL51530A publication Critical patent/IL51530A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL51530A 1976-03-11 1977-02-24 Imidazolyl (thiazolyl) methyl-thioalkyl amidinoformic (sulfinic) acid derivatives,process for their preparation and pharmalceutical compositions containing them IL51530A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9750/76A GB1574214A (en) 1976-03-11 1976-03-11 Amidines

Publications (1)

Publication Number Publication Date
IL51530A true IL51530A (en) 1981-03-31

Family

ID=9878056

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51530A IL51530A (en) 1976-03-11 1977-02-24 Imidazolyl (thiazolyl) methyl-thioalkyl amidinoformic (sulfinic) acid derivatives,process for their preparation and pharmalceutical compositions containing them

Country Status (34)

Country Link
US (4) US4118502A (de)
JP (1) JPS52136170A (de)
AR (2) AR218242A1 (de)
AT (1) AT358576B (de)
AU (1) AU506146B2 (de)
BE (1) BE852324A (de)
CA (1) CA1075700A (de)
CS (1) CS196352B2 (de)
DD (1) DD128616A5 (de)
DE (1) DE2710326A1 (de)
DK (1) DK96477A (de)
ES (1) ES456735A1 (de)
FI (1) FI770736A (de)
FR (1) FR2343730A1 (de)
GB (1) GB1574214A (de)
GR (1) GR62562B (de)
HU (1) HU176611B (de)
IE (1) IE44786B1 (de)
IL (1) IL51530A (de)
IN (1) IN147036B (de)
IT (1) IT1075494B (de)
LU (1) LU76930A1 (de)
MW (1) MW977A1 (de)
NL (1) NL7702533A (de)
NO (1) NO770854L (de)
NZ (1) NZ183396A (de)
OA (1) OA05595A (de)
PL (1) PL105620B1 (de)
PT (1) PT66255B (de)
RO (1) RO73006A (de)
SE (1) SE7702771L (de)
SU (2) SU814274A3 (de)
ZA (1) ZA771018B (de)
ZM (1) ZM2677A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210658A (en) * 1977-09-08 1980-07-01 Smith Kline & French Laboratories Limited Amidinosulphonic acid derivatives
EP0006679B1 (de) 1978-05-24 1982-07-21 Imperial Chemical Industries Plc Anti-Sekretion Thiadiazol-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
US4282213A (en) * 1978-06-06 1981-08-04 Smith Kline & French Laboratories Limited Amidino and guanidino phosphonates
US4242351A (en) * 1979-05-07 1980-12-30 Imperial Chemical Industries Limited Antisecretory oxadiazoles and pharmaceutical compositions containing them
IT8020734A0 (it) * 1980-03-18 1980-03-18 Turconi Franco Quadrata (2 aminoetil)-tiometilderivati del 4-metil-5 aperta par.chiusa par. quadrata-imidazolo adattivita' terapeutica.
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
IT1201523B (it) * 1982-05-18 1989-02-02 Angeli Inst Spa Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
US5399706A (en) * 1993-03-02 1995-03-21 H. B. Fuller Licensing & Financing, Inc. Imidazolidinone diamine and derivatives thereof
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
US3808336A (en) * 1970-06-25 1974-04-30 Smithkline Corp Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives
US3734924A (en) * 1970-10-14 1973-05-22 Smith Kline French Lab Carboxamidines
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1421999A (en) 1973-02-08 1976-01-21 Smith Kline French Lab Heterocyclic containing sulphoxides
US4056620A (en) * 1973-02-08 1977-11-01 Smith Kline & French Laboratories Limited Sulphoxides
US4046907A (en) * 1973-05-17 1977-09-06 Smith Kline & French Laboratories Limited Imidazole alkylaminoethylene compounds
US4025527A (en) * 1973-07-13 1977-05-24 Smith Kline & French Laboratories Limited Certain thiazoles and oxazoles
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
US4140783A (en) * 1976-05-24 1979-02-20 Smith Kline & French Laboratories Limited Isothiazole and isoxazole sulphoxides
GB1602458A (en) 1977-05-05 1981-11-11 Smith Kline French Lab Bisamidines as histamine h2-antagonists

Also Published As

Publication number Publication date
PT66255A (en) 1977-04-01
FR2343730A1 (fr) 1977-10-07
AU2315577A (en) 1978-09-14
BE852324A (fr) 1977-09-12
IE44786B1 (en) 1982-03-24
AT358576B (de) 1980-09-25
HU176611B (en) 1981-03-28
PT66255B (en) 1978-08-07
DE2710326A1 (de) 1977-09-15
DK96477A (da) 1977-09-12
GR62562B (en) 1979-05-10
ZA771018B (en) 1978-01-25
FI770736A (de) 1977-09-12
JPS52136170A (en) 1977-11-14
LU76930A1 (de) 1977-07-12
AU506146B2 (en) 1979-12-13
AR219955A1 (es) 1980-09-30
SU814274A3 (ru) 1981-03-15
FR2343730B1 (de) 1980-01-11
ATA154177A (de) 1980-02-15
CS196352B2 (en) 1980-03-31
AR218242A1 (es) 1980-05-30
RO73006A (ro) 1982-04-12
NZ183396A (en) 1979-03-28
IT1075494B (it) 1985-04-22
US4308275A (en) 1981-12-29
ZM2677A1 (en) 1978-07-21
MW977A1 (en) 1978-08-09
IE44786L (en) 1977-09-11
PL196568A1 (pl) 1978-01-16
NL7702533A (nl) 1977-09-13
SE7702771L (sv) 1977-09-14
PL105620B1 (pl) 1979-10-31
CA1075700A (en) 1980-04-15
OA05595A (fr) 1981-04-30
DD128616A5 (de) 1977-11-30
NO770854L (no) 1977-09-13
IN147036B (de) 1979-10-27
SU731896A3 (ru) 1980-04-30
US4118502A (en) 1978-10-03
US4438127A (en) 1984-03-20
GB1574214A (en) 1980-09-03
ES456735A1 (es) 1978-06-01
US4395419A (en) 1983-07-26

Similar Documents

Publication Publication Date Title
DE2960222D1 (en) Phenoxyalkylcarboxylic-acid derivatives, process for their preparation and medicaments containing them
GB1556919A (en) Piperidylindole derivatives processes for preparing them and pharmaceutical compositions containing them
PH14401A (en) Hydroxyaminohydrocarbonphosphonic acid derivatives,compositions containing same and method of use
IL52663A (en) 4-phenoxy-4-imidazolo(1,2,4-triazolo)-butanoic acid derivatives, process for their preparation and fungicidal compositions containing them
IL51530A (en) Imidazolyl (thiazolyl) methyl-thioalkyl amidinoformic (sulfinic) acid derivatives,process for their preparation and pharmalceutical compositions containing them
DE2964209D1 (en) Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
DE2961983D1 (en) Pyrrolidine-2-methanol derivatives, process for their preparation and medicaments containing them
IL59782A (en) Benzoxazolyl(thiazolyl)oxy-phenoxyalkanoic acid derivatives,process for their preparation and herbicidal compositions containing them
IL54069A (en) 14,15-dihydro-20,21-dinoreburnamenin-14-ol derivatives,process for preparing them and pharmaceutical compositions containing them
GB1543004A (en) 7-aminothiazolylacetamido-cephalosporanic acid derivatives processes for preparing them and pharmaceutical compositions containing them
DE2963228D1 (en) Urea derivatives, processes for preparing them and compositions containing them
PH13924A (en) Glavulanic acid derivatives,pharmaceutical compositions containing same and method of preparation thereof
JPS5318526A (en) Phenoxyyalkanone acid derivatives*process for preparation thereof and composition containing same
MY8500936A (en) Acyl substituted benzimidazole-2-carboxylic acid derivatives, methods for their preparation and compositions containing them
IL60468A (en) 4-sulfamoylphenyl-2-phenyl-imino-1,3-thiazole derivatives,process for their preparation and pharmaceutical compositions containing them
IL52148A (en) Substituted 1-phenoxy-2-hydroxy-3-aminopropanes,process for preparing same and pharmaceutical compositions containing them
DE2964198D1 (en) Indanamine derivatives, process for their preparation and medicaments containing them
IL55427A0 (en) 2-hydrazonopropionic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL59760A0 (en) 7-oxo-4-thia-1-aza-bicyclo(3,2,0)-heptane-2-carboxylic acid derivatives,and process for their preparation
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
IL57533A (en) 17alpha-acetylene derivatives of androst-4-ene,process for preparing them and pharmaceutical compositions containing them
IL52207A (en) Substituted 2-vinyl-chromones, process for their preparation and pharmaceutical compositions containing them
HK96984A (en) Glucofuranosyl-nitrosourea derivatives,processes for their preparation and medicaments containing them
DE2960205D1 (en) 4-hydroxy-2-benzimidazolin-thion derivatives, process for their preparation and medicaments containing them
HK58085A (en) Novel azathianaphthalene derivatives,process for their manufacture,pharmaceutical preparations containing them and their use