IL49132A - 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them - Google Patents

16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL49132A
IL49132A IL49132A IL4913276A IL49132A IL 49132 A IL49132 A IL 49132A IL 49132 A IL49132 A IL 49132A IL 4913276 A IL4913276 A IL 4913276A IL 49132 A IL49132 A IL 49132A
Authority
IL
Israel
Prior art keywords
androst
disubstituted
ones
preparation
pharmaceutical compositions
Prior art date
Application number
IL49132A
Other languages
English (en)
Other versions
IL49132A0 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Priority to IL58505A priority Critical patent/IL58505A/xx
Publication of IL49132A0 publication Critical patent/IL49132A0/xx
Publication of IL49132A publication Critical patent/IL49132A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
IL49132A 1975-03-21 1976-03-02 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them IL49132A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL58505A IL58505A (en) 1975-03-21 1976-03-02 16,1l-disubstituted androst-5-ene derivatives and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB11819/75A GB1538227A (en) 1975-03-21 1975-03-21 16,16-disubstituted steroids of the androstene series

Publications (2)

Publication Number Publication Date
IL49132A0 IL49132A0 (en) 1976-05-31
IL49132A true IL49132A (en) 1980-05-30

Family

ID=9993275

Family Applications (2)

Application Number Title Priority Date Filing Date
IL49132A IL49132A (en) 1975-03-21 1976-03-02 16,1l-disubstituted androst-4-en-3-ones,their preparation and pharmaceutical compositions containing them
IL58505A IL58505A0 (en) 1975-03-21 1979-10-19 16,16-disubstituted androst-5-ene derivatives and their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL58505A IL58505A0 (en) 1975-03-21 1979-10-19 16,16-disubstituted androst-5-ene derivatives and their preparation

Country Status (15)

Country Link
JP (2) JPS51118756A (ru)
AT (1) AT357700B (ru)
AU (1) AU501246B2 (ru)
BE (1) BE839751A (ru)
CA (1) CA1069498A (ru)
CH (2) CH621560A5 (ru)
DE (1) DE2610497C2 (ru)
DK (1) DK143757C (ru)
FR (2) FR2304345A1 (ru)
GB (1) GB1538227A (ru)
IE (1) IE42308B1 (ru)
IL (2) IL49132A (ru)
NL (1) NL184111C (ru)
SE (2) SE7603410L (ru)
ZA (1) ZA761324B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602960A (en) * 1977-05-25 1981-11-18 Beecham Group Ltd Process for preparing 16,16-disubstituted steroids of the androstene series
DE2943778A1 (de) * 1979-10-26 1981-05-07 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung
DE3514272A1 (de) * 1985-04-17 1986-10-23 Schering AG, 1000 Berlin und 4709 Bergkamen Dermatica
JPS63300153A (ja) * 1987-05-29 1988-12-07 日本碍子株式会社 建築用ほうろうパネル
GB9021546D0 (en) * 1990-10-04 1990-11-21 Beecham Group Plc Novel composition
JPH06502161A (ja) * 1990-10-31 1994-03-10 ビーチャム・グループ・パブリック・リミテッド・カンパニー レチノイド浸透作用エンハンサーを含む局所用組成物
GB9205194D0 (en) * 1992-03-10 1992-04-22 Smithkline Beecham Plc Novel composition
JPWO2003051903A1 (ja) * 2001-12-19 2005-04-28 中外製薬株式会社 7位及び17位に置換基を有するアンドロスタン誘導体
CN108558975B (zh) * 2018-04-26 2021-03-02 昆明理工大学 12β-羟基-雄甾4,14-二烯-16-酮类化合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853926A (en) * 1973-05-29 1974-12-10 Searle & Co 17{62 -hydroxy-16,16-dimethylester-4-en-3-one

Also Published As

Publication number Publication date
DE2610497A1 (de) 1976-10-07
CH621560A5 (en) 1981-02-13
NL7602949A (nl) 1976-09-23
CA1069498A (en) 1980-01-08
AT357700B (de) 1980-07-25
JPS61178920A (ja) 1986-08-11
NL184111C (nl) 1989-04-17
IL58505A0 (en) 1980-01-31
SE7902256L (sv) 1979-03-13
NL184111B (nl) 1988-11-16
IL49132A0 (en) 1976-05-31
CH631996A5 (en) 1982-09-15
SE7603410L (sv) 1976-09-22
JPS6355488B2 (ru) 1988-11-02
BE839751A (fr) 1976-09-20
AU501246B2 (en) 1979-06-14
FR2304345A1 (fr) 1976-10-15
IE42308B1 (en) 1980-07-16
JPS625920B2 (ru) 1987-02-07
JPS51118756A (en) 1976-10-18
DE2610497C2 (de) 1986-10-16
DK123476A (da) 1976-09-22
GB1538227A (en) 1979-01-10
IE42308L (en) 1976-09-21
AU1220776A (en) 1977-09-22
DK143757C (da) 1982-03-22
FR2304345B1 (ru) 1980-11-07
ATA191376A (de) 1979-12-15
DK143757B (da) 1981-10-05
FR2445340A1 (fr) 1980-07-25
ZA761324B (en) 1977-02-23
FR2445340B1 (ru) 1983-02-11

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