IL48749A - Substituted benzamide (or heterocyclic carboxamide) derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

Substituted benzamide (or heterocyclic carboxamide) derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL48749A
IL48749A IL48749A IL4874975A IL48749A IL 48749 A IL48749 A IL 48749A IL 48749 A IL48749 A IL 48749A IL 4874975 A IL4874975 A IL 4874975A IL 48749 A IL48749 A IL 48749A
Authority
IL
Israel
Prior art keywords
derivatives
preparation
pharmaceutical compositions
substituted benzamide
heterocyclic carboxamide
Prior art date
Application number
IL48749A
Other languages
English (en)
Other versions
IL48749A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL48749A0 publication Critical patent/IL48749A0/xx
Publication of IL48749A publication Critical patent/IL48749A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
IL48749A 1975-01-03 1975-12-28 Substituted benzamide (or heterocyclic carboxamide) derivatives,their preparation and pharmaceutical compositions comprising them IL48749A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2500157A DE2500157C2 (de) 1975-01-03 1975-01-03 N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
IL48749A0 IL48749A0 (en) 1976-02-29
IL48749A true IL48749A (en) 1979-09-30

Family

ID=5935941

Family Applications (1)

Application Number Title Priority Date Filing Date
IL48749A IL48749A (en) 1975-01-03 1975-12-28 Substituted benzamide (or heterocyclic carboxamide) derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (24)

Country Link
US (1) US4221815A (da)
JP (1) JPS51131846A (da)
AT (1) AT347922B (da)
AU (1) AU501010B2 (da)
BE (1) BE837311A (da)
CA (1) CA1064933A (da)
CH (1) CH619209A5 (da)
DE (1) DE2500157C2 (da)
DK (1) DK276A (da)
EG (1) EG12067A (da)
ES (1) ES443910A1 (da)
FI (1) FI753721A (da)
FR (1) FR2296407A1 (da)
GB (1) GB1538482A (da)
HU (1) HU174325B (da)
IE (1) IE42391B1 (da)
IL (1) IL48749A (da)
IT (1) IT1052091B (da)
LU (1) LU74129A1 (da)
NL (1) NL7515129A (da)
NO (1) NO760003L (da)
PT (1) PT64670B (da)
SE (1) SE7600012L (da)
ZA (1) ZA767B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2517229A1 (de) * 1975-04-18 1976-10-28 Boehringer Mannheim Gmbh Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung
DE2639935A1 (de) * 1976-09-04 1978-03-09 Hoechst Ag Benzoesaeuren und verfahren zu ihrer herstellung
DE2706977A1 (de) * 1977-02-18 1978-08-24 Hoechst Ag Benzoesaeuren und deren derivate sowie verfahren zu ihrer herstellung
LU79008A1 (de) * 1978-02-03 1979-09-06 Byk Gulden Lomberg Chem Fab W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel
DE3063878D1 (en) * 1979-07-13 1983-07-28 Thomae Gmbh Dr K Derivatives of carboxylic acids, their preparation and medicaments containing them
EP0029320B1 (en) * 1979-11-15 1985-07-10 Beecham Group Plc Secondary ethanol amines, their preparation and their use in pharmaceutical compositions
DE3100535A1 (de) * 1981-01-10 1982-08-12 Dr. Karl Thomae Gmbh, 7950 Biberach "neue carbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel"
DE3211934A1 (de) * 1982-03-31 1983-10-13 Hoechst Ag, 6230 Frankfurt Salicylsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung
PT77219B (fr) * 1982-08-24 1986-02-04 May & Baker Ltd Procede de preparation des derives de la benzamide
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
GB8708833D0 (en) * 1987-04-13 1987-05-20 Lilly S A E Organic compounds
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823042D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823040D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
JP3001632B2 (ja) * 1990-03-20 2000-01-24 首藤 紘一 安息香酸誘導体の新規製造法
CA2057324A1 (en) * 1990-12-18 1992-06-19 Lora Louise Fitch Benzamide and sulfonamide hypoglycemic agents
US6916489B2 (en) * 1992-06-15 2005-07-12 Emisphere Technologies, Inc. Active agent transport systems
US20010003001A1 (en) * 1993-04-22 2001-06-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
SI9720025A (sl) 1996-03-29 1999-08-31 Emishphere Technologies, Inc. Spojine in sestavki za prenos aktivne snovi
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6194458B1 (en) * 1998-10-30 2001-02-27 Merck & Co., Inc. Benzamide potassium channel inhibitors
EP1175390B1 (en) 1999-04-05 2005-02-02 Emisphere Technologies, Inc. Disodium salts, monohydrates, and ethanol solvates
JP4850379B2 (ja) * 1999-12-16 2012-01-11 エミスフェアー・テクノロジーズ・インク 活性剤を輸送するための化合物及び組成物
TWI282786B (en) * 2000-04-28 2007-06-21 Nihon Nohyaku Co Ltd A process for preparing 2-halogenobenzoic acids
IL156064A0 (en) * 2000-12-28 2003-12-23 Daiichi Seiyaku Co Vla-4 inhibitors
WO2005009992A1 (ja) 2003-07-24 2005-02-03 Daiichi Pharmaceutical Co., Ltd. シクロヘキサンカルボン酸類
EA009201B1 (ru) 2003-09-03 2007-12-28 Пфайзер Инк. Фенил - или пиридиламидные соединения в качестве антагонистов простагландина e2
JP2005209106A (ja) * 2004-01-26 2005-08-04 Nec Corp 携帯通信端末、受信メール管理方法、プログラムおよび記録媒体
CA2565660C (en) * 2004-05-04 2009-11-03 Pfizer Inc. Ortho substituted aryl or heteroaryl amide compounds
US7951973B2 (en) * 2005-11-22 2011-05-31 Bayer Cropscience Ag N-(1-methyl-2Phenylethyl)benzamide derivatives
WO2007121578A1 (en) * 2006-04-24 2007-11-01 Merck Frosst Canada Ltd. Indole amide derivatives as ep4 receptor antagonists
WO2012003145A2 (en) * 2010-07-02 2012-01-05 Allergan, Inc. Therapeutic agents for ocular hypertension
US9714238B2 (en) 2010-07-02 2017-07-25 Allergan, Inc. Therapeutic agents for ocular hypertension
AR091429A1 (es) 2012-06-29 2015-02-04 Lilly Co Eli Compuestos de fenoxietil piperidina
TWI636046B (zh) 2013-05-17 2018-09-21 美國禮來大藥廠 苯氧基乙基二氫－１ｈ－異喹啉化合物
US9776964B2 (en) 2013-12-17 2017-10-03 Eli Lilly And Company Phenoxyethyl cyclic amine derivatives and their activity as EP4 receptor modulators
CA3036245C (en) * 2016-09-13 2021-07-20 Arbutus Biopharma Corporation Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3100226A (en) * 1959-10-16 1963-08-06 Amchem Prod 2,5 dichloro-3 acylaminobenzoic acids
US3536753A (en) * 1969-05-27 1970-10-27 Geigy Chem Corp O-(substituted benzamido)phenylacetic acids
US3636094A (en) * 1969-07-25 1972-01-18 Searle & Co Norbornanecarboxylic acid amides of anthranilic acid
FR2088225A1 (en) * 1970-05-29 1972-01-07 Ugine Kuhlmann Substd salicylanilides - having antiuric props
US3855285A (en) * 1971-06-21 1974-12-17 Pfizer Acylmethylthio-trifluoromethyl-benzoic acids
DE2230383C3 (de) * 1971-10-01 1981-12-03 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben
DE2320387A1 (de) * 1973-04-21 1974-10-31 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben

Also Published As

Publication number Publication date
CH619209A5 (da) 1980-09-15
HU174325B (hu) 1979-12-28
AU8796475A (en) 1977-07-07
FR2296407A1 (fr) 1976-07-30
ES443910A1 (es) 1977-04-16
FR2296407B1 (da) 1979-06-29
AT347922B (de) 1979-01-25
AU501010B2 (en) 1979-06-07
GB1538482A (en) 1979-01-17
BE837311A (fr) 1976-07-05
US4221815A (en) 1980-09-09
CA1064933A (en) 1979-10-23
JPS51131846A (en) 1976-11-16
PT64670B (fr) 1977-08-08
NL7515129A (nl) 1976-07-06
NO760003L (da) 1976-07-06
IL48749A0 (en) 1976-02-29
DE2500157A1 (de) 1976-07-22
IT1052091B (it) 1981-06-20
ZA767B (en) 1976-12-29
FI753721A (da) 1976-07-04
IE42391B1 (en) 1980-07-30
DE2500157C2 (de) 1983-09-15
ATA1876A (de) 1978-06-15
LU74129A1 (da) 1976-11-11
IE42391L (en) 1976-07-03
DK276A (da) 1976-07-04
SE7600012L (sv) 1976-07-05
PT64670A (fr) 1976-05-01
EG12067A (en) 1978-12-31

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