IL48452A - Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them - Google Patents

Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them

Info

Publication number
IL48452A
IL48452A IL48452A IL4845275A IL48452A IL 48452 A IL48452 A IL 48452A IL 48452 A IL48452 A IL 48452A IL 4845275 A IL4845275 A IL 4845275A IL 48452 A IL48452 A IL 48452A
Authority
IL
Israel
Prior art keywords
preparationand
quinuclidines
dioxolane
spiro
pharmaceutical compositions
Prior art date
Application number
IL48452A
Other languages
English (en)
Other versions
IL48452A0 (en
Inventor
Cohen Sasson
A Fisher
Original Assignee
Purdue Frederick Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Frederick Co filed Critical Purdue Frederick Co
Priority to IL48452A priority Critical patent/IL48452A/xx
Publication of IL48452A0 publication Critical patent/IL48452A0/xx
Priority to US05/656,056 priority patent/US4104397A/en
Priority to AR265266A priority patent/AR213102A1/es
Priority to FI763151A priority patent/FI60015C/fi
Priority to DE19762650845 priority patent/DE2650845A1/de
Priority to ZA766662A priority patent/ZA766662B/xx
Priority to NZ182555A priority patent/NZ182555A/xx
Priority to NL7612426A priority patent/NL7612426A/xx
Priority to DK507276A priority patent/DK148744C/da
Priority to SE7612526A priority patent/SE426700B/xx
Priority to NO763819A priority patent/NO145618C/no
Priority to FR7634033A priority patent/FR2331343A1/fr
Priority to CA265,346A priority patent/CA1071629A/en
Priority to GB7646747A priority patent/GB1542494A/en
Priority to BE172273A priority patent/BE848228A/xx
Priority to ES453161A priority patent/ES453161A1/es
Priority to CH1417676A priority patent/CH626085A5/de
Priority to JP51136166A priority patent/JPS5277092A/ja
Priority to AT839376A priority patent/AT356652B/de
Priority to MX765118U priority patent/MX4395E/es
Priority to AU19554/76A priority patent/AU507660B2/en
Priority to ES460286A priority patent/ES460286A1/es
Priority to AR270024A priority patent/AR214652A1/es
Priority to IN766/CAL/78A priority patent/IN147506B/en
Priority to AT105179A priority patent/AT357555B/de
Publication of IL48452A publication Critical patent/IL48452A/xx
Priority to DK281985A priority patent/DK281985A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL48452A 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them IL48452A (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
IL48452A IL48452A (en) 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them
US05/656,056 US4104397A (en) 1975-11-11 1976-02-06 Spiro (1,3-dioxolane-4,3') quinuclidine compounds
AR265266A AR213102A1 (es) 1975-11-11 1976-10-28 Procedimiento para obtener compuestos de espiro(1,3-dioxalan-4,3')quinuclidina y sus sales
FI763151A FI60015C (fi) 1975-11-11 1976-11-03 Foerfarande foer framstaellning av nya 2-substituerade sprio(1,3-dioxolan-4,3')kinuklidiner med kolinergisk effekt
DE19762650845 DE2650845A1 (de) 1975-11-11 1976-11-06 Neue spiro-(1,3-dioxolan-4,3')- quinuclidine
ZA766662A ZA766662B (en) 1975-11-11 1976-11-08 New quinuclidine compounds
NZ182555A NZ182555A (en) 1975-11-11 1976-11-08 Spiro(1,3-dioxalane-4,3)-quinuclidine derivatives and pharmaceutical compositions
NL7612426A NL7612426A (nl) 1975-11-11 1976-11-09 Werkwijze voor de bereiding van nieuwe spiro(1,3- -dioxolan-4,3')chinuclidineverbindingen.
CH1417676A CH626085A5 (no) 1975-11-11 1976-11-10
CA265,346A CA1071629A (en) 1975-11-11 1976-11-10 Spiro(1, 3-dioxolane-4, 3') quinuclidine compounds
SE7612526A SE426700B (sv) 1975-11-11 1976-11-10 Analogiforfarande for framstellning av spiro-(1,3-dioxolan-4,3')-kinuklidiner med terapeutisk verkan
NO763819A NO145618C (no) 1975-11-11 1976-11-10 Analogifremgangsmaate ved fremstilling av nye, terapeutisk aktive spiro-(1,3-dioxolan-4,3`-kinuclidin-forbindelser
FR7634033A FR2331343A1 (fr) 1975-11-11 1976-11-10 Nouvelle spiro(1,3-dioxolane-4,3')quinuclidine, son procede de preparation et medicament la contenant
DK507276A DK148744C (da) 1975-11-11 1976-11-10 Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf
GB7646747A GB1542494A (en) 1975-11-11 1976-11-10 Spiro(1,3-dioxolane-4,3')-quinuclidine compounds
BE172273A BE848228A (fr) 1975-11-11 1976-11-10 Nouveaux composes de spiro (1,3-dioxolane-4,3') quinuclidine,
ES453161A ES453161A1 (es) 1975-11-11 1976-11-10 Un procedimiento de preparacion de espiro (1,3-dioxolan-4,3)quinuclidinas.
AU19554/76A AU507660B2 (en) 1975-11-11 1976-11-11 Quinuclidine compounds
JP51136166A JPS5277092A (en) 1975-11-11 1976-11-11 Spiro*1*33dioxolanee4*3**quinucridine process for preparing same and medical composition containing same
AT839376A AT356652B (de) 1975-11-11 1976-11-11 Verfahren zum herstellen von neuen spiro-(1,3- -dioxolan-4,3') chinuclidinen, ihren salzen und isomeren
MX765118U MX4395E (es) 1975-11-11 1976-11-11 Procedimiento para la preparacion de derivados del espiro(1-3 dioxolano 4,3')quinuclidinas
ES460286A ES460286A1 (es) 1975-11-11 1977-06-30 Un procedimiento de preparacion de espiro(1,3-dioxolan-4,3) quinuclidina.
AR270024A AR214652A1 (es) 1975-11-11 1977-11-18 Procedimiento para obtener compuestos de espiro(1,3-dioxolan-4,3')quinuclidina y sus sales
IN766/CAL/78A IN147506B (no) 1975-11-11 1978-07-11
AT105179A AT357555B (de) 1975-11-11 1979-02-12 Verfahren zum herstellen von neuen spiro-(1,3- dioxolan-4,3')chinuclidinen, ihren salzen und isomeren
DK281985A DK281985A (da) 1975-11-11 1985-06-21 Analogifremgangsmaade til fremstilling af 2,2-diphenyl-spiro-(1,3-dioxolan-4,3')quinuclidin eller farmaceutisk acceptable syreadditionssalte deraf

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL48452A IL48452A (en) 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
IL48452A0 IL48452A0 (en) 1976-01-30
IL48452A true IL48452A (en) 1979-07-25

Family

ID=11048545

Family Applications (1)

Application Number Title Priority Date Filing Date
IL48452A IL48452A (en) 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them

Country Status (20)

Country Link
US (1) US4104397A (no)
JP (1) JPS5277092A (no)
AR (2) AR213102A1 (no)
AT (1) AT356652B (no)
AU (1) AU507660B2 (no)
BE (1) BE848228A (no)
CA (1) CA1071629A (no)
CH (1) CH626085A5 (no)
DE (1) DE2650845A1 (no)
DK (1) DK148744C (no)
ES (2) ES453161A1 (no)
FI (1) FI60015C (no)
FR (1) FR2331343A1 (no)
GB (1) GB1542494A (no)
IL (1) IL48452A (no)
MX (1) MX4395E (no)
NL (1) NL7612426A (no)
NO (1) NO145618C (no)
NZ (1) NZ182555A (no)
ZA (1) ZA766662B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2454056A1 (fr) * 1979-03-15 1980-11-07 Geissmann Robert Cheminee cinetique pouvant etre utilisee comme rotissoire
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
JPS61167130A (ja) * 1985-01-17 1986-07-28 Nissan Motor Co Ltd 内燃機関の吸気装置
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
ES2074441T3 (es) * 1987-10-05 1995-09-16 Yamanouchi Pharma Co Ltd Compuestos espiro heterociclicos y su preparacion.
US4876260A (en) * 1987-10-28 1989-10-24 State Of Israel, Israel Institute Of Biological Research Oxathiolanes
JPH01164409A (ja) * 1987-12-18 1989-06-28 Nippon Paint Co Ltd 浄化装置
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
EP0984970B1 (en) 1997-05-30 2003-11-19 Neurosearch A/S Spiro-quinuclidine derivatives, their preparation and use
JP4564135B2 (ja) * 1999-07-26 2010-10-20 住友化学株式会社 高純度フェノチアジン化合物とその製造方法、およびその中間体の製造方法、並びにその中間体の原料の水和物と新規結晶
WO2008073067A1 (en) * 2006-08-02 2008-06-19 Janssen Pharmaceutica N.V. Novel spiro-quinuclidinyl derivatives for the treatment of the central nervous system disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones

Also Published As

Publication number Publication date
AU1955476A (en) 1978-05-18
FI60015C (fi) 1981-11-10
DK148744C (da) 1986-02-03
NO145618C (no) 1982-04-28
GB1542494A (en) 1979-03-21
US4104397A (en) 1978-08-01
DE2650845A1 (de) 1977-05-18
AT356652B (de) 1980-05-12
AR214652A1 (es) 1979-07-13
FI60015B (fi) 1981-07-31
NO763819L (no) 1977-05-12
NZ182555A (en) 1979-01-11
ATA839376A (de) 1979-10-15
AU507660B2 (en) 1980-02-21
IL48452A0 (en) 1976-01-30
CH626085A5 (no) 1981-10-30
DK507276A (da) 1977-05-12
NO145618B (no) 1982-01-18
NL7612426A (nl) 1977-05-13
JPS5277092A (en) 1977-06-29
ZA766662B (en) 1977-10-26
FI763151A (no) 1977-05-12
MX4395E (es) 1982-04-23
ES453161A1 (es) 1977-11-01
BE848228A (fr) 1977-03-01
JPS6259113B2 (no) 1987-12-09
CA1071629A (en) 1980-02-12
FR2331343B1 (no) 1980-04-04
AR213102A1 (es) 1978-12-15
DK148744B (da) 1985-09-16
ES460286A1 (es) 1978-04-01
FR2331343A1 (fr) 1977-06-10

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