IL47770A - 18-methyl-19-nor-20-keto-pregnanes and process for their manufacture - Google Patents
18-methyl-19-nor-20-keto-pregnanes and process for their manufactureInfo
- Publication number
- IL47770A IL47770A IL47770A IL4777075A IL47770A IL 47770 A IL47770 A IL 47770A IL 47770 A IL47770 A IL 47770A IL 4777075 A IL4777075 A IL 4777075A IL 47770 A IL47770 A IL 47770A
- Authority
- IL
- Israel
- Prior art keywords
- pregnanes
- keto
- methyl
- manufacture
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2438020A DE2438020A1 (de) | 1974-08-05 | 1974-08-05 | 18-methyl-19-nor-20-keto-pregnane und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL47770A0 IL47770A0 (en) | 1975-10-15 |
| IL47770A true IL47770A (en) | 1978-10-31 |
Family
ID=5922668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL47770A IL47770A (en) | 1974-08-05 | 1975-07-23 | 18-methyl-19-nor-20-keto-pregnanes and process for their manufacture |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4029777A (cs) |
| JP (1) | JPS5141347A (cs) |
| AT (1) | AT345998B (cs) |
| BE (1) | BE832124A (cs) |
| CA (1) | CA1037027A (cs) |
| CH (1) | CH611910A5 (cs) |
| CS (2) | CS175498B2 (cs) |
| DD (1) | DD120192A5 (cs) |
| DE (1) | DE2438020A1 (cs) |
| DK (1) | DK136369C (cs) |
| ES (1) | ES439720A1 (cs) |
| FR (1) | FR2281123A1 (cs) |
| GB (1) | GB1512258A (cs) |
| HU (1) | HU171684B (cs) |
| IL (1) | IL47770A (cs) |
| NL (1) | NL7509326A (cs) |
| SE (1) | SE404804B (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61144199A (ja) * | 1984-12-18 | 1986-07-01 | Pioneer Electronic Corp | スピ−カ用紙製振動部材の製造方法 |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| JPH03500049A (ja) * | 1987-08-25 | 1991-01-10 | ジー、ケルビン・ダブリュー | ストレス、不安および発作活性の緩和のための組成物および方法 |
| US5175154A (en) * | 1987-11-25 | 1992-12-29 | Research Corporation Technologies, Inc. | 5 α-pregnan-20-ones and 5-pregnen-20-ones and related compounds |
| RS58297B1 (sr) | 2013-04-17 | 2019-03-29 | Sage Therapeutics Inc | 19-nor c3,3-disupstituisani c21-n-pirazolil steroidi i postupci za njihovu upotrebu |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| PT2986624T (pt) | 2013-04-17 | 2020-07-07 | Sage Therapeutics Inc | Esteroides neuroativos 19-nor para métodos de tratamento |
| ES2864719T3 (es) | 2013-07-19 | 2021-10-14 | Sage Therapeutics Inc | Esteroides neuroactivos, composiciones y usos de los mismos |
| BR112016003862B1 (pt) | 2013-08-23 | 2022-09-06 | Sage Therapeutics, Inc | Compostos esteroides neuroativos, suas composições e seus usos |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JP6742308B2 (ja) | 2014-10-16 | 2020-08-19 | セージ セラピューティクス， インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| CN117024502A (zh) | 2014-10-16 | 2023-11-10 | 萨奇治疗股份有限公司 | 靶向cns障碍的组合物和方法 |
| JP6893173B2 (ja) | 2014-11-27 | 2021-06-23 | セージ セラピューティクス， インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| SMT202100113T1 (it) | 2015-01-26 | 2021-05-07 | Sage Therapeutics Inc | Composizioni e metodi per trattare disturbi del snc |
| EP4155314A1 (en) | 2015-02-20 | 2023-03-29 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JP7065825B2 (ja) | 2016-07-11 | 2022-05-12 | セージ セラピューティクス， インコーポレイテッド | Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法 |
| JP7049313B2 (ja) | 2016-07-11 | 2022-04-06 | セージ セラピューティクス， インコーポレイテッド | Ｃ１７、ｃ２０、およびｃ２１置換神経刺激性ステロイドおよびそれらの使用方法 |
| JP7382326B2 (ja) * | 2017-12-22 | 2023-11-16 | セージ セラピューティクス， インコーポレイテッド | Ｃｎｓ障害の処置のための組成物および方法 |
| CR20210629A (es) | 2019-05-31 | 2022-03-22 | Sage Therapeutics Inc | Esteroides neuroactivos y composiciones de estos |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1409239A (en) * | 1971-11-11 | 1975-10-08 | Glaxo Lab Ltd | Process for the preparation of 3alpha-hydroxy-5alpha-steroids |
| BE791196A (fr) * | 1971-11-11 | 1973-05-10 | Glaxo Lab Ltd | Nouveaux steroides, leur procede de preparation et leurs applications |
-
1974
- 1974-08-05 DE DE2438020A patent/DE2438020A1/de not_active Withdrawn
-
1975
- 1975-07-22 CS CS5170A patent/CS175498B2/cs unknown
- 1975-07-22 CS CS215A patent/CS175500B2/cs unknown
- 1975-07-23 IL IL47770A patent/IL47770A/xx unknown
- 1975-07-24 ES ES439720A patent/ES439720A1/es not_active Expired
- 1975-07-29 DK DK344475A patent/DK136369C/da active
- 1975-08-01 DD DD187639A patent/DD120192A5/xx unknown
- 1975-08-01 CA CA232,730A patent/CA1037027A/en not_active Expired
- 1975-08-01 AT AT600475A patent/AT345998B/de not_active IP Right Cessation
- 1975-08-04 HU HU75SCHE529A patent/HU171684B/hu unknown
- 1975-08-04 SE SE7508777A patent/SE404804B/xx unknown
- 1975-08-04 FR FR7524225A patent/FR2281123A1/fr not_active Withdrawn
- 1975-08-04 GB GB32477/75A patent/GB1512258A/en not_active Expired
- 1975-08-05 JP JP50095322A patent/JPS5141347A/ja active Pending
- 1975-08-05 NL NL7509326A patent/NL7509326A/xx not_active Application Discontinuation
- 1975-08-05 US US05/602,098 patent/US4029777A/en not_active Expired - Lifetime
- 1975-08-05 BE BE158941A patent/BE832124A/xx unknown
- 1975-08-05 CH CH1020975A patent/CH611910A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK136369B (da) | 1977-10-03 |
| FR2281123A1 (fr) | 1976-03-05 |
| DK344475A (da) | 1976-02-06 |
| GB1512258A (en) | 1978-05-24 |
| ATA600475A (de) | 1978-02-15 |
| HU171684B (hu) | 1978-02-28 |
| AT345998B (de) | 1978-10-10 |
| ES439720A1 (es) | 1977-03-01 |
| US4029777A (en) | 1977-06-14 |
| DD120192A5 (cs) | 1976-06-05 |
| AU8351575A (en) | 1977-02-03 |
| CH611910A5 (cs) | 1979-06-29 |
| DE2438020A1 (de) | 1976-02-26 |
| CS175500B2 (cs) | 1977-05-31 |
| IL47770A0 (en) | 1975-10-15 |
| CA1037027A (en) | 1978-08-22 |
| SE7508777L (sv) | 1976-02-06 |
| DK136369C (da) | 1978-02-27 |
| JPS5141347A (en) | 1976-04-07 |
| CS175498B2 (cs) | 1977-05-31 |
| SE404804B (sv) | 1978-10-30 |
| NL7509326A (nl) | 1976-02-09 |
| BE832124A (fr) | 1976-02-05 |
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