IL47770A - 18-methyl-19-nor-20-keto-pregnanes and process for their manufacture - Google Patents

18-methyl-19-nor-20-keto-pregnanes and process for their manufacture

Info

Publication number
IL47770A
IL47770A IL47770A IL4777075A IL47770A IL 47770 A IL47770 A IL 47770A IL 47770 A IL47770 A IL 47770A IL 4777075 A IL4777075 A IL 4777075A IL 47770 A IL47770 A IL 47770A
Authority
IL
Israel
Prior art keywords
pregnanes
keto
methyl
manufacture
Prior art date
Application number
IL47770A
Other languages
English (en)
Other versions
IL47770A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL47770A0 publication Critical patent/IL47770A0/xx
Publication of IL47770A publication Critical patent/IL47770A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
IL47770A 1974-08-05 1975-07-23 18-methyl-19-nor-20-keto-pregnanes and process for their manufacture IL47770A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2438020A DE2438020A1 (de) 1974-08-05 1974-08-05 18-methyl-19-nor-20-keto-pregnane und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL47770A0 IL47770A0 (en) 1975-10-15
IL47770A true IL47770A (en) 1978-10-31

Family

ID=5922668

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47770A IL47770A (en) 1974-08-05 1975-07-23 18-methyl-19-nor-20-keto-pregnanes and process for their manufacture

Country Status (17)

Country Link
US (1) US4029777A (xx)
JP (1) JPS5141347A (xx)
AT (1) AT345998B (xx)
BE (1) BE832124A (xx)
CA (1) CA1037027A (xx)
CH (1) CH611910A5 (xx)
CS (2) CS175498B2 (xx)
DD (1) DD120192A5 (xx)
DE (1) DE2438020A1 (xx)
DK (1) DK136369C (xx)
ES (1) ES439720A1 (xx)
FR (1) FR2281123A1 (xx)
GB (1) GB1512258A (xx)
HU (1) HU171684B (xx)
IL (1) IL47770A (xx)
NL (1) NL7509326A (xx)
SE (1) SE404804B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61144199A (ja) * 1984-12-18 1986-07-01 Pioneer Electronic Corp スピ−カ用紙製振動部材の製造方法
EP0382790A4 (en) * 1987-08-25 1991-03-27 Kelvin W. Gee Compositions and methods for alleviating stress, anxiety and seizure activity
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
US5175154A (en) * 1987-11-25 1992-12-29 Research Corporation Technologies, Inc. 5 α-pregnan-20-ones and 5-pregnen-20-ones and related compounds
CN117304245A (zh) 2013-04-17 2023-12-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
CN105339381B (zh) 2013-04-17 2018-04-27 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
RS61733B1 (sr) 2013-07-19 2021-05-31 Sage Therapeutics Inc Neuroaktivni steroidi, njihove kompozicije i upotrebe
HUE052308T2 (hu) 2013-08-23 2021-04-28 Sage Therapeutics Inc Neuroaktív szteroidok, készítmények és alkalmazásuk
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
ES2808855T3 (es) 2014-10-16 2021-03-02 Sage Therapeutics Inc Composiciones y métodos para tratar trastornos del SNC
NZ769008A (en) 2014-10-16 2024-03-22 Sage Therapeutics Inc Compositions and methods for treating cns disorders
PT3224269T (pt) 2014-11-27 2020-06-01 Sage Therapeutics Inc Composições e métodos para tratamento de distúrbios do snc
ES2857082T3 (es) 2015-01-26 2021-09-28 Sage Therapeutics Inc Composiciones y métodos para el tratamiento de trastornos del SNC
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CA3030413A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
EP4406602A2 (en) 2016-07-11 2024-07-31 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
CN118271387A (zh) * 2017-12-22 2024-07-02 萨奇治疗股份有限公司 治疗cns疾病的组合物和方法
AR119047A1 (es) 2019-05-31 2021-11-17 Sage Therapeutics Inc Esteroides neuroactivos como moduladores de gabaa y su uso en el tratamiento de trastornos del snc

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1409239A (en) * 1971-11-11 1975-10-08 Glaxo Lab Ltd Process for the preparation of 3alpha-hydroxy-5alpha-steroids
BE791196A (fr) * 1971-11-11 1973-05-10 Glaxo Lab Ltd Nouveaux steroides, leur procede de preparation et leurs applications

Also Published As

Publication number Publication date
DK136369C (da) 1978-02-27
ES439720A1 (es) 1977-03-01
JPS5141347A (en) 1976-04-07
HU171684B (hu) 1978-02-28
ATA600475A (de) 1978-02-15
AU8351575A (en) 1977-02-03
NL7509326A (nl) 1976-02-09
FR2281123A1 (fr) 1976-03-05
BE832124A (fr) 1976-02-05
GB1512258A (en) 1978-05-24
SE7508777L (sv) 1976-02-06
US4029777A (en) 1977-06-14
CS175500B2 (xx) 1977-05-31
DD120192A5 (xx) 1976-06-05
CH611910A5 (xx) 1979-06-29
IL47770A0 (en) 1975-10-15
DE2438020A1 (de) 1976-02-26
DK136369B (da) 1977-10-03
AT345998B (de) 1978-10-10
CA1037027A (en) 1978-08-22
DK344475A (da) 1976-02-06
CS175498B2 (xx) 1977-05-31
SE404804B (sv) 1978-10-30

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