IL47361A - 8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof - Google Patents

8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof

Info

Publication number
IL47361A
IL47361A IL47361A IL4736175A IL47361A IL 47361 A IL47361 A IL 47361A IL 47361 A IL47361 A IL 47361A IL 4736175 A IL4736175 A IL 4736175A IL 47361 A IL47361 A IL 47361A
Authority
IL
Israel
Prior art keywords
substituted
preparation
ergoline derivatives
methyl ergoline
methyl
Prior art date
Application number
IL47361A
Other languages
English (en)
Other versions
IL47361A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL47361A0 publication Critical patent/IL47361A0/xx
Publication of IL47361A publication Critical patent/IL47361A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL47361A 1974-05-28 1975-05-26 8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof IL47361A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO1272A HU169073B (zh) 1974-05-28 1974-05-28

Publications (2)

Publication Number Publication Date
IL47361A0 IL47361A0 (en) 1975-07-28
IL47361A true IL47361A (en) 1979-11-30

Family

ID=10996767

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47361A IL47361A (en) 1974-05-28 1975-05-26 8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof

Country Status (21)

Country Link
US (1) US4005089A (zh)
JP (1) JPS5218718B2 (zh)
AT (1) AT346501B (zh)
BE (1) BE829518A (zh)
BG (1) BG27374A3 (zh)
CA (1) CA1051878A (zh)
CS (1) CS194227B2 (zh)
DD (1) DD121639A5 (zh)
DE (1) DE2523743A1 (zh)
DK (1) DK143801C (zh)
ES (1) ES437994A1 (zh)
FI (1) FI61897C (zh)
FR (1) FR2272671B1 (zh)
GB (1) GB1474337A (zh)
HU (1) HU169073B (zh)
IL (1) IL47361A (zh)
NL (1) NL7506276A (zh)
PL (1) PL98944B1 (zh)
SE (1) SE419548B (zh)
SU (1) SU625612A3 (zh)
YU (1) YU135575A (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
HU172479B (hu) * 1976-03-09 1978-09-28 Gyogyszerkutato Intezet Sposob poluchenija novykh soedinenij s ehrgolenovymi i
JPS577172Y2 (zh) * 1977-03-17 1982-02-10
JPS582957U (ja) * 1981-06-30 1983-01-10 松下電子工業株式会社 高圧ナトリウムランプ
IT1171432B (it) * 1981-08-03 1987-06-10 Fidia Farmaceutici Amidi organiche derivate da lipidi azotati utilizzabili come farmaci
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
DD238051A1 (de) * 1985-06-10 1986-08-06 Dresden Arzneimittel Verfahren zur herstellung neuer lysergsaeureamide
US8710092B2 (en) * 2009-12-23 2014-04-29 Map Pharmaceuticals, Inc. Substituted indolo 4,3 FG quinolines useful for treating migraine
BR112013033339A2 (pt) 2011-06-23 2016-08-16 Map Pharmaceuticals Inc análogos de fluorergolina
SG11201403434YA (en) 2011-12-19 2014-09-26 Map Pharmaceuticals Inc Novel iso-ergoline derivatives
EP2793583A4 (en) 2011-12-21 2015-08-12 Map Pharmaceuticals Inc NOVEL NEUROMODULATORY CONNECTIONS
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
BR112019025420A2 (pt) 2017-06-01 2020-06-16 Xoc Pharmaceuticals, Inc. Compostos policíclicos e usos destes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533699A (en) * 1950-12-12 Amines containing the king system
US2673850A (en) * 1951-07-28 1954-03-30 Sandoz Ag Piperazides of the lysergic acid series
US2946796A (en) * 1958-10-15 1960-07-26 Grace W R & Co Salts of ergot alkaloids
CH475252A (de) * 1966-02-08 1969-07-15 Sandoz Ag Verfahren zur Herstellung neuer Lysergsäure-Derivate
SE396753B (sv) * 1970-05-18 1977-10-03 Richter Gedeon Vegyeszet Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien
US3901893A (en) * 1970-05-18 1975-08-26 Richter Gedeon Vegyeszet New dihydro-lysergic acid derivative
IL41409A (en) * 1972-02-04 1977-04-29 Richter Gedeon Vegyeszet Lysergic acid amides and process for their preparation

Also Published As

Publication number Publication date
NL7506276A (nl) 1975-12-02
ATA386375A (de) 1978-03-15
IL47361A0 (en) 1975-07-28
BG27374A3 (en) 1979-10-12
DD121639A5 (zh) 1976-08-12
DK143801C (da) 1982-03-22
FI61897B (fi) 1982-06-30
SE7505974L (sv) 1975-12-01
FR2272671B1 (zh) 1978-10-06
FI61897C (fi) 1982-10-11
CS194227B2 (en) 1979-11-30
GB1474337A (en) 1977-05-25
JPS5218718B2 (zh) 1977-05-24
CA1051878A (en) 1979-04-03
DK143801B (da) 1981-10-12
ES437994A1 (es) 1977-01-16
FR2272671A1 (zh) 1975-12-26
PL98944B1 (pl) 1978-05-31
HU169073B (zh) 1976-09-28
AU8142575A (en) 1976-11-25
FI751537A (zh) 1975-11-29
SE419548B (sv) 1981-08-10
US4005089A (en) 1977-01-25
SU625612A3 (ru) 1978-09-25
AT346501B (de) 1978-11-10
BE829518A (fr) 1975-09-15
JPS516998A (zh) 1976-01-20
DK235175A (da) 1975-11-29
YU135575A (en) 1982-06-30
DE2523743A1 (de) 1975-12-18

Similar Documents

Publication Publication Date Title
HU173108B (hu) Sposob poluchenija novykh proizvodnykh izoindolinil-, pirrolopirazinil-, oksatiinopirrolil- i ditiinopirrolil-oksi-karbonil-piperazina
HU171420B (hu) Sposob poluchenija proizvodnykh sul'fonamido-piridina i piridin-tiadiazina
YU37156B (en) Process for preparing 1-z3-(naphthyl-1-yloxy)-2-hydroxy-propylc-piperazine derivatives
YU188475A (en) Process for preparing aclacynomycin a and b
HU173590B (hu) Sposob poluchenija proizvodnykh d-6-metil-8-tiometil-ehrgolina
IL47361A (en) 8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof
YU39113B (en) Process for preparing 2-arylamino-2-imidazoline derivatives
HU172431B (hu) Sposob poluchenija proizvodnykh fenola
GB1533991A (en) Diacylnucleosides and process for preparing the same
HU172493B (hu) Sposob poluchenija proizvodnykh tienobenzodiazepina
PH16594A (en) Ergoline derivatives
IL49681A0 (en) New eburnamenine derivatives and a process for the preparation thereof
GB1535214A (en) Ergoline derivatives
GB1486493A (en) Cephalosporin derivatives and process for preparing same
HU173740B (hu) Sposob poluchenija proizvodnykh aza-digidro-prostaglandina
GB1519050A (en) Indolo-quinolizine derivatives and a process for the preparation thereof
GB1516509A (en) Omikron-phenylenediamine derivatives and process for their preparation
IL47268A0 (en) New benzodiazepine derivatives and a process for the preparation thereof
AU8208175A (en) Hexahydro-diazepino-indole derivatives and a process for their preparation
GB1533453A (en) Epoxy-androstanes and a process for the preparation thereof
HU174300B (hu) Sposob poluchenija proizvodnykh 1-acil-4-/o-galofenil/-tiosemikarbazida
IL48030A (en) 14-substituted 3,16-trans-eburnamentine derivatives and a process for the preparation thereof
CY1098A (en) Pharmazeutical compositions and a process for the preparation thereof
IL47169A0 (en) Indoloquinolizine compounds and a process for the preparation thereof
IL45139A (en) Substituted nitrobenzophenone derivatives and a process for the preparation thereof