IL45289A - Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type - Google Patents

Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type

Info

Publication number
IL45289A
IL45289A IL45289A IL4528974A IL45289A IL 45289 A IL45289 A IL 45289A IL 45289 A IL45289 A IL 45289A IL 4528974 A IL4528974 A IL 4528974A IL 45289 A IL45289 A IL 45289A
Authority
IL
Israel
Prior art keywords
preperation
benzodiazepin
dihydro
ones
phenyl
Prior art date
Application number
IL45289A
Other languages
English (en)
Other versions
IL45289A0 (en
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of IL45289A0 publication Critical patent/IL45289A0/xx
Publication of IL45289A publication Critical patent/IL45289A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL45289A 1973-07-30 1974-07-17 Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type IL45289A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1105673A CH573928A5 (pt) 1973-07-30 1973-07-30

Publications (2)

Publication Number Publication Date
IL45289A0 IL45289A0 (en) 1974-10-22
IL45289A true IL45289A (en) 1979-12-30

Family

ID=4369623

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45289A IL45289A (en) 1973-07-30 1974-07-17 Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type

Country Status (21)

Country Link
US (1) US4010153A (pt)
JP (1) JPS5041886A (pt)
AR (1) AR202224A1 (pt)
AT (1) AT337192B (pt)
BE (1) BE818047A (pt)
CA (1) CA1021778A (pt)
CH (1) CH573928A5 (pt)
DE (1) DE2436744A1 (pt)
DK (1) DK138798B (pt)
ES (1) ES428675A1 (pt)
FI (1) FI227474A (pt)
FR (1) FR2239464B1 (pt)
GB (1) GB1481219A (pt)
HU (1) HU169180B (pt)
IE (1) IE39904B1 (pt)
IL (1) IL45289A (pt)
NL (1) NL7410256A (pt)
NO (1) NO137897C (pt)
SE (2) SE7409708L (pt)
SU (1) SU528872A3 (pt)
ZA (1) ZA744635B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
AU2016297024B2 (en) 2015-07-22 2021-03-04 Enanta Pharmaceuticals, Inc. Benzodiazepine derivatives as RSV inhibitors
EP3402799B1 (en) 2016-01-15 2022-05-04 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
EP3582784B1 (en) 2017-02-16 2022-06-08 Enanta Pharmaceuticals, Inc. Processes for the preparation of benzodiazepine derivatives
WO2018226801A1 (en) 2017-06-07 2018-12-13 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as rsv inhibitors
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019006291A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019067864A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. PHARMACEUTICAL AGENTS IN COMBINATION AS INHIBITORS OF RSV
CA3080138A1 (en) * 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
WO2019094920A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as rsv inhibitors
WO2019199908A1 (en) 2018-04-11 2019-10-17 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
MX2021011144A (es) 2019-03-18 2022-01-18 Enanta Pharm Inc Derivados de las benzodiazepinas como inhibidores del vsr.
WO2020210246A1 (en) 2019-04-09 2020-10-15 Enanta Pharmaceuticals, Inc, Heterocyclic compounds as rsv inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
JPS4426302Y1 (pt) * 1966-04-22 1969-11-05

Also Published As

Publication number Publication date
NO137897B (no) 1978-02-06
DK138798C (pt) 1979-04-09
FI227474A (pt) 1975-01-31
NO742739L (pt) 1975-02-24
SU528872A3 (ru) 1976-09-15
ES428675A1 (es) 1976-09-01
CH573928A5 (pt) 1976-03-31
HU169180B (pt) 1976-10-28
SE7409708L (pt) 1975-01-31
BE818047A (fr) 1974-11-18
ZA744635B (en) 1975-08-27
IE39904B1 (en) 1979-01-31
US4010153A (en) 1977-03-01
IE39904L (en) 1975-01-30
DE2436744A1 (de) 1975-02-27
CA1021778A (en) 1977-11-29
AT337192B (de) 1977-06-10
ATA567674A (de) 1976-10-15
FR2239464B1 (pt) 1978-04-14
NL7410256A (nl) 1975-02-03
IL45289A0 (en) 1974-10-22
DK138798B (da) 1978-10-30
FR2239464A1 (pt) 1975-02-28
DK393274A (pt) 1975-04-01
NO137897C (no) 1978-05-16
GB1481219A (en) 1977-07-27
AR202224A1 (es) 1975-05-23
JPS5041886A (pt) 1975-04-16
SE7510823L (sv) 1975-09-26

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