IL45200A - 16 ,17 -cyclopentylidenedioxy-9 -fluoro-11 ,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate and anti-inflammatory compositions comprising it - Google Patents

16 ,17 -cyclopentylidenedioxy-9 -fluoro-11 ,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate and anti-inflammatory compositions comprising it

Info

Publication number
IL45200A
IL45200A IL45200A IL4520074A IL45200A IL 45200 A IL45200 A IL 45200A IL 45200 A IL45200 A IL 45200A IL 4520074 A IL4520074 A IL 4520074A IL 45200 A IL45200 A IL 45200A
Authority
IL
Israel
Prior art keywords
cyclopentylidenedioxy
pregnadiene
dione
dihydroxy
fluoro
Prior art date
Application number
IL45200A
Other languages
English (en)
Other versions
IL45200A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL45200A0 publication Critical patent/IL45200A0/xx
Publication of IL45200A publication Critical patent/IL45200A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL45200A 1973-08-17 1974-07-05 16 ,17 -cyclopentylidenedioxy-9 -fluoro-11 ,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate and anti-inflammatory compositions comprising it IL45200A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38930273A 1973-08-17 1973-08-17

Publications (2)

Publication Number Publication Date
IL45200A0 IL45200A0 (en) 1974-11-29
IL45200A true IL45200A (en) 1978-08-31

Family

ID=23537694

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45200A IL45200A (en) 1973-08-17 1974-07-05 16 ,17 -cyclopentylidenedioxy-9 -fluoro-11 ,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate and anti-inflammatory compositions comprising it

Country Status (17)

Country Link
US (1) US4158055A (xx)
JP (1) JPS557407B2 (xx)
BE (1) BE818929A (xx)
CH (1) CH601353A5 (xx)
CY (1) CY946A (xx)
DE (1) DE2437847C3 (xx)
FR (1) FR2240738B1 (xx)
GB (1) GB1442925A (xx)
HK (1) HK44778A (xx)
HU (1) HU172213B (xx)
IE (1) IE39738B1 (xx)
IL (1) IL45200A (xx)
KE (1) KE2820A (xx)
MY (1) MY7800234A (xx)
NL (1) NL184899C (xx)
PH (1) PH12415A (xx)
ZA (1) ZA744259B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA763131B (en) * 1975-05-27 1978-01-25 Syntex Inc Use of flunisolide to treat respiratory diseases
DE10326899A1 (de) * 2003-06-14 2004-12-30 Beiersdorf Ag Kosmetische Zubereitungen mit stabilisierten Konservierungsmitteln
AR045536A1 (es) * 2003-08-29 2005-11-02 Ranbaxy Lab Ltd Inhibidores de la fosfodiesterasa tipo -iv
WO2005028495A1 (en) * 2003-09-24 2005-03-31 Glaxo Group Limited Anti-inflammatory glucocorticoids
EP1694655A2 (en) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
EP1948167A1 (en) * 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Compositions of phosphodiesterase type iv inhibitors
US20090221664A1 (en) 2005-10-19 2009-09-03 Abhijit Ray Pharmaceutical compositions of muscarinic receptor antagonists
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
CA2664247A1 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
MX2009009793A (es) * 2007-03-14 2009-10-16 Ranbaxy Lab Ltd Derivados de pirazolo (3,4-b) piridina como inhibidores de fosfodiesterasa.
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same
CN113698448B (zh) * 2021-10-29 2022-02-22 山东谷雨春生物科技有限公司 一种安西奈德的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB894810A (en) * 1959-10-05 1962-04-26 American Cyanamid Co Aqueous pharmaceutical solutions containing anti-inflammatory steroids
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
GB928150A (en) * 1961-02-08 1963-06-06 Upjohn Co Topical pharmaceutical compositions comprising steroids and flavonoids
US3053836A (en) * 1961-07-14 1962-09-11 Olin Mathieson Acetals and ketals of 16alpha, 17alpha-dihydroxyprogesterones
US3541602A (en) * 1968-07-29 1970-11-17 Squibb & Sons Inc Acetonides of 9-halogenated 3beta,11beta,10alpha,17alpha,21-pentahydroxypregnanes
GB1382614A (en) * 1972-01-10 1975-02-05 Squibb & Sons Inc Steroid compositions
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base

Also Published As

Publication number Publication date
ZA744259B (en) 1975-06-25
DE2437847C3 (de) 1981-03-12
FR2240738B1 (xx) 1980-04-11
NL184899B (nl) 1989-07-03
PH12415A (en) 1979-02-07
JPS557407B2 (xx) 1980-02-25
MY7800234A (en) 1978-12-31
BE818929A (fr) 1975-02-17
IE39738B1 (en) 1978-12-20
AU7073674A (en) 1976-01-08
NL184899C (nl) 1989-12-01
IE39738L (en) 1975-02-17
FR2240738A1 (xx) 1975-03-14
JPS5058211A (xx) 1975-05-21
NL7410613A (nl) 1975-02-19
HK44778A (en) 1978-08-18
GB1442925A (en) 1976-07-14
IL45200A0 (en) 1974-11-29
CY946A (en) 1978-06-23
DE2437847B2 (de) 1980-06-19
KE2820A (en) 1978-03-10
CH601353A5 (xx) 1978-07-14
HU172213B (hu) 1978-07-28
DE2437847A1 (de) 1975-02-27
US4158055A (en) 1979-06-12

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