PH12415A - 16a,17-cyclopentylidenedioxy-9a-fluoro-11,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate,anti-inflammatory composition and method of use thereof - Google Patents

16a,17-cyclopentylidenedioxy-9a-fluoro-11,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate,anti-inflammatory composition and method of use thereof

Info

Publication number
PH12415A
PH12415A PH16097A PH16097A PH12415A PH 12415 A PH12415 A PH 12415A PH 16097 A PH16097 A PH 16097A PH 16097 A PH16097 A PH 16097A PH 12415 A PH12415 A PH 12415A
Authority
PH
Philippines
Prior art keywords
cyclopentylidenedioxy
pregnadiene
dione
dihydroxy
fluoro
Prior art date
Application number
PH16097A
Other languages
English (en)
Inventor
G Sieger
W Shultz
C Krieger
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH12415A publication Critical patent/PH12415A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH16097A 1973-08-17 1974-07-26 16a,17-cyclopentylidenedioxy-9a-fluoro-11,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate,anti-inflammatory composition and method of use thereof PH12415A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38930273A 1973-08-17 1973-08-17

Publications (1)

Publication Number Publication Date
PH12415A true PH12415A (en) 1979-02-07

Family

ID=23537694

Family Applications (1)

Application Number Title Priority Date Filing Date
PH16097A PH12415A (en) 1973-08-17 1974-07-26 16a,17-cyclopentylidenedioxy-9a-fluoro-11,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate,anti-inflammatory composition and method of use thereof

Country Status (17)

Country Link
US (1) US4158055A (xx)
JP (1) JPS557407B2 (xx)
BE (1) BE818929A (xx)
CH (1) CH601353A5 (xx)
CY (1) CY946A (xx)
DE (1) DE2437847C3 (xx)
FR (1) FR2240738B1 (xx)
GB (1) GB1442925A (xx)
HK (1) HK44778A (xx)
HU (1) HU172213B (xx)
IE (1) IE39738B1 (xx)
IL (1) IL45200A (xx)
KE (1) KE2820A (xx)
MY (1) MY7800234A (xx)
NL (1) NL184899C (xx)
PH (1) PH12415A (xx)
ZA (1) ZA744259B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA763131B (en) * 1975-05-27 1978-01-25 Syntex Inc Use of flunisolide to treat respiratory diseases
DE10326899A1 (de) * 2003-06-14 2004-12-30 Beiersdorf Ag Kosmetische Zubereitungen mit stabilisierten Konservierungsmitteln
CA2537185A1 (en) * 2003-08-29 2005-03-10 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
WO2005028495A1 (en) * 2003-09-24 2005-03-31 Glaxo Group Limited Anti-inflammatory glucocorticoids
EP1694655A2 (en) * 2003-11-26 2006-08-30 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
RU2008119322A (ru) * 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Композиции ингибиторов фосфодиэстеразы iv типа
KR20090069309A (ko) * 2006-09-22 2009-06-30 랜박시 래보러터리스 리미티드 포스포디에스터라제 타입-ⅳ의 저해제
WO2008035316A2 (en) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
NZ579645A (en) 2007-03-14 2012-01-12 Ranbaxy Lab Ltd Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same
CN113698448B (zh) * 2021-10-29 2022-02-22 山东谷雨春生物科技有限公司 一种安西奈德的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB894810A (en) * 1959-10-05 1962-04-26 American Cyanamid Co Aqueous pharmaceutical solutions containing anti-inflammatory steroids
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
GB928150A (en) * 1961-02-08 1963-06-06 Upjohn Co Topical pharmaceutical compositions comprising steroids and flavonoids
US3053836A (en) * 1961-07-14 1962-09-11 Olin Mathieson Acetals and ketals of 16alpha, 17alpha-dihydroxyprogesterones
US3541602A (en) * 1968-07-29 1970-11-17 Squibb & Sons Inc Acetonides of 9-halogenated 3beta,11beta,10alpha,17alpha,21-pentahydroxypregnanes
GB1382614A (en) * 1972-01-10 1975-02-05 Squibb & Sons Inc Steroid compositions
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base

Also Published As

Publication number Publication date
IL45200A (en) 1978-08-31
CH601353A5 (xx) 1978-07-14
MY7800234A (en) 1978-12-31
NL184899C (nl) 1989-12-01
IE39738L (en) 1975-02-17
GB1442925A (en) 1976-07-14
FR2240738A1 (xx) 1975-03-14
HU172213B (hu) 1978-07-28
DE2437847B2 (de) 1980-06-19
FR2240738B1 (xx) 1980-04-11
BE818929A (fr) 1975-02-17
ZA744259B (en) 1975-06-25
KE2820A (en) 1978-03-10
US4158055A (en) 1979-06-12
AU7073674A (en) 1976-01-08
NL184899B (nl) 1989-07-03
IE39738B1 (en) 1978-12-20
DE2437847A1 (de) 1975-02-27
HK44778A (en) 1978-08-18
IL45200A0 (en) 1974-11-29
JPS5058211A (xx) 1975-05-21
CY946A (en) 1978-06-23
DE2437847C3 (de) 1981-03-12
JPS557407B2 (xx) 1980-02-25
NL7410613A (nl) 1975-02-19

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