IL43295A - Antibiotic substance MB 321 and its manufacture - Google Patents
Antibiotic substance MB 321 and its manufactureInfo
- Publication number
- IL43295A IL43295A IL43295A IL4329573A IL43295A IL 43295 A IL43295 A IL 43295A IL 43295 A IL43295 A IL 43295A IL 4329573 A IL4329573 A IL 4329573A IL 43295 A IL43295 A IL 43295A
- Authority
- IL
- Israel
- Prior art keywords
- antibacterial
- water
- antibiotic
- absorption spectrum
- elemental analysis
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 11
- 230000003115 biocidal effect Effects 0.000 title abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 39
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 19
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 10
- 238000000862 absorption spectrum Methods 0.000 claims abstract description 9
- 235000015097 nutrients Nutrition 0.000 claims abstract description 8
- 244000005700 microbiome Species 0.000 claims abstract description 6
- 150000003839 salts Chemical class 0.000 claims abstract description 6
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 5
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 5
- 238000000921 elemental analysis Methods 0.000 claims abstract 6
- 230000003287 optical effect Effects 0.000 claims abstract 6
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- 238000000034 method Methods 0.000 claims description 11
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- 150000001875 compounds Chemical class 0.000 claims description 4
- 230000002401 inhibitory effect Effects 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 150000001720 carbohydrates Chemical class 0.000 claims 3
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- 241000187681 Nocardia sp. Species 0.000 abstract description 11
- 229910052799 carbon Inorganic materials 0.000 abstract description 9
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- 239000000969 carrier Substances 0.000 abstract 1
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- 231100000636 lethal dose Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229960002160 maltose Drugs 0.000 description 1
- 229960001855 mannitol Drugs 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical class ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 description 1
- 229960004961 mechlorethamine Drugs 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- NKAAEMMYHLFEFN-UHFFFAOYSA-M monosodium tartrate Chemical compound [Na+].OC(=O)C(O)C(O)C([O-])=O NKAAEMMYHLFEFN-UHFFFAOYSA-M 0.000 description 1
- 150000002826 nitrites Chemical class 0.000 description 1
- 238000004810 partition chromatography Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- NGFMICBWJRZIBI-UJPOAAIJSA-N salicin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC=C1CO NGFMICBWJRZIBI-UJPOAAIJSA-N 0.000 description 1
- 229940120668 salicin Drugs 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- -1 starch Chemical compound 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000001974 tryptic soy broth Substances 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29717372A | 1972-10-12 | 1972-10-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL43295A0 IL43295A0 (en) | 1975-08-31 |
| IL43295A true IL43295A (en) | 1977-03-31 |
Family
ID=23145157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL43295A IL43295A (en) | 1972-10-12 | 1973-09-21 | Antibiotic substance MB 321 and its manufacture |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5434838B2 (ro) |
| AR (1) | AR198115A1 (ro) |
| BE (1) | BE806029A (ro) |
| BG (1) | BG23543A3 (ro) |
| CH (1) | CH584287A5 (ro) |
| CS (1) | CS191221B2 (ro) |
| DD (1) | DD111403A5 (ro) |
| DE (1) | DE2351344A1 (ro) |
| ES (1) | ES419574A1 (ro) |
| FR (1) | FR2202680B1 (ro) |
| GB (1) | GB1439668A (ro) |
| HK (1) | HK42977A (ro) |
| HU (1) | HU166799B (ro) |
| IE (1) | IE38136B1 (ro) |
| IL (1) | IL43295A (ro) |
| NL (1) | NL7314099A (ro) |
| PH (1) | PH10065A (ro) |
| PL (1) | PL85814B1 (ro) |
| RO (1) | RO64690A (ro) |
| SE (1) | SE398756B (ro) |
| SU (1) | SU618053A3 (ro) |
| YU (1) | YU265573A (ro) |
| ZA (1) | ZA735897B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1087537A (en) * | 1975-08-21 | 1980-10-14 | John H. E. J. Martin | Antibiotic bm123 and production thereof |
| IL56424A0 (en) * | 1978-02-02 | 1979-03-12 | American Cyanamid Co | Complexes of antibiotic bm123 gamma |
-
1973
- 1973-08-27 IE IE1503/73A patent/IE38136B1/xx unknown
- 1973-08-28 ZA ZA735897A patent/ZA735897B/xx unknown
- 1973-09-10 GB GB4253573A patent/GB1439668A/en not_active Expired
- 1973-09-14 PH PH15013D patent/PH10065A/en unknown
- 1973-09-19 AR AR250150A patent/AR198115A1/es active
- 1973-09-21 IL IL43295A patent/IL43295A/en unknown
- 1973-09-23 SU SU731968937A patent/SU618053A3/ru active
- 1973-10-01 RO RO7300076217A patent/RO64690A/ro unknown
- 1973-10-09 BG BG024692A patent/BG23543A3/xx unknown
- 1973-10-10 YU YU02655/73A patent/YU265573A/xx unknown
- 1973-10-11 DD DD173998A patent/DD111403A5/xx unknown
- 1973-10-11 CH CH1448673A patent/CH584287A5/xx not_active IP Right Cessation
- 1973-10-11 ES ES419574A patent/ES419574A1/es not_active Expired
- 1973-10-11 SE SE7313861A patent/SE398756B/xx unknown
- 1973-10-11 PL PL1973165781A patent/PL85814B1/pl unknown
- 1973-10-12 CS CS737048A patent/CS191221B2/cs unknown
- 1973-10-12 HU HUAE395A patent/HU166799B/hu unknown
- 1973-10-12 JP JP11402473A patent/JPS5434838B2/ja not_active Expired
- 1973-10-12 FR FR7336570A patent/FR2202680B1/fr not_active Expired
- 1973-10-12 DE DE19732351344 patent/DE2351344A1/de not_active Withdrawn
- 1973-10-12 BE BE136647A patent/BE806029A/xx unknown
- 1973-10-12 NL NL7314099A patent/NL7314099A/xx not_active Application Discontinuation
-
1977
- 1977-08-18 HK HK429/77A patent/HK42977A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH584287A5 (ro) | 1977-01-31 |
| AR198115A1 (es) | 1974-05-31 |
| DD111403A5 (ro) | 1975-02-12 |
| JPS4975796A (ro) | 1974-07-22 |
| IE38136B1 (en) | 1978-01-04 |
| FR2202680A1 (ro) | 1974-05-10 |
| GB1439668A (en) | 1976-06-16 |
| HK42977A (en) | 1977-08-26 |
| HU166799B (ro) | 1975-06-28 |
| IE38136L (en) | 1974-04-12 |
| PL85814B1 (ro) | 1976-04-30 |
| ZA735897B (en) | 1974-07-31 |
| AU5995173A (en) | 1975-03-06 |
| ES419574A1 (es) | 1976-04-01 |
| SE398756B (sv) | 1978-01-16 |
| BG23543A3 (bg) | 1977-09-15 |
| NL7314099A (ro) | 1974-04-16 |
| IL43295A0 (en) | 1975-08-31 |
| PH10065A (en) | 1976-08-03 |
| SU618053A3 (ru) | 1978-07-30 |
| BE806029A (fr) | 1974-04-12 |
| JPS5434838B2 (ro) | 1979-10-29 |
| YU265573A (en) | 1981-11-13 |
| DE2351344A1 (de) | 1974-04-25 |
| CS191221B2 (en) | 1979-06-29 |
| FR2202680B1 (ro) | 1976-04-09 |
| RO64690A (fr) | 1979-01-15 |
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