IL42546A - Preparation of N) diethylaminoethyl (2 - methoxy - 4 - amino - 5 - chlorobenzamide - Google Patents
Preparation of N) diethylaminoethyl (2 - methoxy - 4 - amino - 5 - chlorobenzamideInfo
- Publication number
- IL42546A IL42546A IL42546A IL4254673A IL42546A IL 42546 A IL42546 A IL 42546A IL 42546 A IL42546 A IL 42546A IL 4254673 A IL4254673 A IL 4254673A IL 42546 A IL42546 A IL 42546A
- Authority
- IL
- Israel
- Prior art keywords
- methoxy
- chlorobenzamide
- amino
- reacting
- diethylaminoethyl
- Prior art date
Links
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 title abstract 2
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract 2
- 239000011707 mineral Substances 0.000 claims abstract 2
- 150000007522 mineralic acids Chemical class 0.000 claims abstract 2
- 150000007524 organic acids Chemical class 0.000 claims abstract 2
- 239000002253 acid Substances 0.000 claims 2
- 150000004820 halides Chemical class 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 235000005985 organic acids Nutrition 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 1
- VKPPFDPXZWFDFA-UHFFFAOYSA-N 2-chloroethanamine Chemical compound NCCCl VKPPFDPXZWFDFA-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-methoxy-4-acetamido- 5-chlorobenzoyl halide Chemical class 0.000 abstract 1
- UJBLIKMTKGJYLA-UHFFFAOYSA-N 4-acetamido-5-chloro-N-(2-chloroethyl)-2-methoxybenzamide Chemical compound ClCCNC(C1=C(C=C(C(=C1)Cl)NC(C)=O)OC)=O UJBLIKMTKGJYLA-UHFFFAOYSA-N 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222695A FR2281353A1 (fr) | 1972-06-22 | 1972-06-22 | Nouveau procede de preparation du n(diethylaminoethyl) 2-methoxy 4-amino 5-chlorobenzamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42546A0 IL42546A0 (en) | 1973-08-29 |
| IL42546A true IL42546A (en) | 1976-11-30 |
Family
ID=9100674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42546A IL42546A (en) | 1972-06-22 | 1973-06-19 | Preparation of N) diethylaminoethyl (2 - methoxy - 4 - amino - 5 - chlorobenzamide |
Country Status (20)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2528037A1 (fr) * | 1982-06-08 | 1983-12-09 | Centre Nat Rech Scient | Procede de preparation de phenolamides |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1233877B (de) * | 1961-07-25 | 1967-02-09 | Ile De France | Verfahren zur Herstellung von substituierten N-(tert. Aminoalkyl)-benzamiden |
-
1972
- 1972-06-22 FR FR7222695A patent/FR2281353A1/fr active Granted
-
1973
- 1973-06-08 MC MC1049A patent/MC1008A1/xx unknown
- 1973-06-13 GB GB2820473A patent/GB1395132A/en not_active Expired
- 1973-06-18 HU HUSO1087A patent/HU166935B/hu unknown
- 1973-06-18 BG BG023904A patent/BG21398A3/xx unknown
- 1973-06-18 BE BE1005165A patent/BE801037A/xx not_active IP Right Cessation
- 1973-06-19 AT AT536973A patent/AT350045B/de not_active IP Right Cessation
- 1973-06-19 DE DE2331262A patent/DE2331262A1/de active Pending
- 1973-06-19 CS CS4411A patent/CS168034B2/cs unknown
- 1973-06-19 IE IE1006/73A patent/IE37822B1/xx unknown
- 1973-06-19 IL IL42546A patent/IL42546A/en unknown
- 1973-06-19 CA CA174,389A patent/CA992559A/fr not_active Expired
- 1973-06-20 ES ES416099A patent/ES416099A1/es not_active Expired
- 1973-06-20 LU LU67829A patent/LU67829A1/xx unknown
- 1973-06-20 KR KR7300972A patent/KR780000254B1/ko not_active Expired
- 1973-06-20 DD DD171686A patent/DD108283A5/xx unknown
- 1973-06-21 ZA ZA734193A patent/ZA734193B/xx unknown
- 1973-06-21 CH CH906473A patent/CH570971A5/xx not_active IP Right Cessation
- 1973-06-21 AU AU57213/73A patent/AU468922B2/en not_active Expired
- 1973-06-22 YU YU1693/73A patent/YU36692B/xx unknown
Also Published As
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