GB1395132A - Preparation of benzamide derivatives - Google Patents
Preparation of benzamide derivativesInfo
- Publication number
- GB1395132A GB1395132A GB2820473A GB2820473A GB1395132A GB 1395132 A GB1395132 A GB 1395132A GB 2820473 A GB2820473 A GB 2820473A GB 2820473 A GB2820473 A GB 2820473A GB 1395132 A GB1395132 A GB 1395132A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methoxy
- chlorobenzamide
- acetamido
- diethylamino
- june
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1395132 N - [2 - (N,N - diethylamino)ethyl]- 2 - methoxy - 4 - amino - 5 - chlorobenzamide SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE 13 June 1973 [22 June 1972] 28204/73 Heading C2C N - [2 - (N<SP>1</SP>,N<SP>1</SP> - diethylamino)ethyl] - 2- methoxy - 4 - amino - 5 - chlorobenzamide is prepared by reacting a 2-methoxy-4-acetamido- 5-chlorobenzoyl halide with 2-chloroethylamine and reacting the resulting N-(2-chloroethyl) - 2 - methoxy - 4 - acetamido - 5 - chlorobenzamide with diethylamine, followed by alkaline hydrolysis, and may be converted to its pharmaceutically acceptable mineral or organic acid addition salts and its quaternary ammonium salts.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222695A FR2281353A1 (en) | 1972-06-22 | 1972-06-22 | NEW PROCESS FOR THE PREPARATION OF N (DIETHYLAMINOETHYL) 2-METHOXY 4-AMINO 5-CHLOROBENZAMIDE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1395132A true GB1395132A (en) | 1975-05-21 |
Family
ID=9100674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2820473A Expired GB1395132A (en) | 1972-06-22 | 1973-06-13 | Preparation of benzamide derivatives |
Country Status (20)
| Country | Link |
|---|---|
| KR (1) | KR780000254B1 (en) |
| AT (1) | AT350045B (en) |
| AU (1) | AU468922B2 (en) |
| BE (1) | BE801037A (en) |
| BG (1) | BG21398A3 (en) |
| CA (1) | CA992559A (en) |
| CH (1) | CH570971A5 (en) |
| CS (1) | CS168034B2 (en) |
| DD (1) | DD108283A5 (en) |
| DE (1) | DE2331262A1 (en) |
| ES (1) | ES416099A1 (en) |
| FR (1) | FR2281353A1 (en) |
| GB (1) | GB1395132A (en) |
| HU (1) | HU166935B (en) |
| IE (1) | IE37822B1 (en) |
| IL (1) | IL42546A (en) |
| LU (1) | LU67829A1 (en) |
| MC (1) | MC1008A1 (en) |
| YU (1) | YU36692B (en) |
| ZA (1) | ZA734193B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523076A1 (en) * | 1984-06-28 | 1986-01-09 | Bristol-Myers Co., New York, N.Y. | SUBSTITUTED BENZAMIDES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2528037A1 (en) * | 1982-06-08 | 1983-12-09 | Centre Nat Rech Scient | PROCESS FOR THE PREPARATION OF PHENOLAMIDES |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1233877B (en) * | 1961-07-25 | 1967-02-09 | Ile De France | Process for the preparation of substituted N- (tert. Aminoalkyl) -benzamides |
-
1972
- 1972-06-22 FR FR7222695A patent/FR2281353A1/en active Granted
-
1973
- 1973-06-08 MC MC1049A patent/MC1008A1/en unknown
- 1973-06-13 GB GB2820473A patent/GB1395132A/en not_active Expired
- 1973-06-18 BG BG023904A patent/BG21398A3/en unknown
- 1973-06-18 BE BE1005165A patent/BE801037A/en not_active IP Right Cessation
- 1973-06-18 HU HUSO1087A patent/HU166935B/hu unknown
- 1973-06-19 IL IL42546A patent/IL42546A/en unknown
- 1973-06-19 IE IE1006/73A patent/IE37822B1/en unknown
- 1973-06-19 CS CS4411A patent/CS168034B2/cs unknown
- 1973-06-19 AT AT536973A patent/AT350045B/en not_active IP Right Cessation
- 1973-06-19 DE DE2331262A patent/DE2331262A1/en active Pending
- 1973-06-19 CA CA174,389A patent/CA992559A/en not_active Expired
- 1973-06-20 DD DD171686A patent/DD108283A5/xx unknown
- 1973-06-20 KR KR7300972A patent/KR780000254B1/en active
- 1973-06-20 ES ES416099A patent/ES416099A1/en not_active Expired
- 1973-06-20 LU LU67829A patent/LU67829A1/xx unknown
- 1973-06-21 ZA ZA734193A patent/ZA734193B/en unknown
- 1973-06-21 AU AU57213/73A patent/AU468922B2/en not_active Expired
- 1973-06-21 CH CH906473A patent/CH570971A5/xx not_active IP Right Cessation
- 1973-06-22 YU YU1693/73A patent/YU36692B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523076A1 (en) * | 1984-06-28 | 1986-01-09 | Bristol-Myers Co., New York, N.Y. | SUBSTITUTED BENZAMIDES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2281353B1 (en) | 1979-03-30 |
| IE37822L (en) | 1973-12-22 |
| HU166935B (en) | 1975-06-28 |
| AU468922B2 (en) | 1976-01-29 |
| BE801037A (en) | 1973-12-18 |
| DD108283A5 (en) | 1974-09-12 |
| ES416099A1 (en) | 1976-02-16 |
| KR780000254B1 (en) | 1978-07-06 |
| ATA536973A (en) | 1978-10-15 |
| AT350045B (en) | 1979-05-10 |
| CH570971A5 (en) | 1975-12-31 |
| CA992559A (en) | 1976-07-06 |
| AU5721373A (en) | 1975-01-09 |
| MC1008A1 (en) | 1974-10-18 |
| YU36692B (en) | 1984-08-31 |
| FR2281353A1 (en) | 1976-03-05 |
| YU169373A (en) | 1982-06-18 |
| CS168034B2 (en) | 1976-05-28 |
| IL42546A0 (en) | 1973-08-29 |
| DE2331262A1 (en) | 1974-01-17 |
| IE37822B1 (en) | 1977-10-26 |
| IL42546A (en) | 1976-11-30 |
| BG21398A3 (en) | 1976-05-20 |
| ZA734193B (en) | 1974-06-26 |
| LU67829A1 (en) | 1974-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |