ES416099A1 - Preparation of benzamide derivatives - Google Patents

Preparation of benzamide derivatives

Info

Publication number
ES416099A1
ES416099A1 ES416099A ES416099A ES416099A1 ES 416099 A1 ES416099 A1 ES 416099A1 ES 416099 A ES416099 A ES 416099A ES 416099 A ES416099 A ES 416099A ES 416099 A1 ES416099 A1 ES 416099A1
Authority
ES
Spain
Prior art keywords
methoxy
chlorobenzamide
diethylaminoethyl
amino
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES416099A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES416099A1 publication Critical patent/ES416099A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Preparation procedure for N (diethylaminoethyl) -2-methoxy-4-amino-5-chlorobenzamide that responds to the formula: **(See formula)** of its addition salts with pharmaceutically acceptable mineral or organic acids, of its quaternary ammonium salts, characterized in that a halide of 2-methoxy-4-acetamido-5-chlorobenzoic acid is reacted with 2-chloroethylamine so that Obtain the N (2-chloroethyl) -2-methoxy-4-acetamino-5-chlorobenzamide, the latter compound being treated with diethylamine to obtain the desired N (diethylaminoethyl) -2-methoxy-4-amino-5-chlorobenzamide. (Machine-translation by Google Translate, not legally binding)
ES416099A 1972-06-22 1973-06-20 Preparation of benzamide derivatives Expired ES416099A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7222695A FR2281353A1 (en) 1972-06-22 1972-06-22 NEW PROCESS FOR THE PREPARATION OF N (DIETHYLAMINOETHYL) 2-METHOXY 4-AMINO 5-CHLOROBENZAMIDE

Publications (1)

Publication Number Publication Date
ES416099A1 true ES416099A1 (en) 1976-02-16

Family

ID=9100674

Family Applications (1)

Application Number Title Priority Date Filing Date
ES416099A Expired ES416099A1 (en) 1972-06-22 1973-06-20 Preparation of benzamide derivatives

Country Status (20)

Country Link
KR (1) KR780000254B1 (en)
AT (1) AT350045B (en)
AU (1) AU468922B2 (en)
BE (1) BE801037A (en)
BG (1) BG21398A3 (en)
CA (1) CA992559A (en)
CH (1) CH570971A5 (en)
CS (1) CS168034B2 (en)
DD (1) DD108283A5 (en)
DE (1) DE2331262A1 (en)
ES (1) ES416099A1 (en)
FR (1) FR2281353A1 (en)
GB (1) GB1395132A (en)
HU (1) HU166935B (en)
IE (1) IE37822B1 (en)
IL (1) IL42546A (en)
LU (1) LU67829A1 (en)
MC (1) MC1008A1 (en)
YU (1) YU36692B (en)
ZA (1) ZA734193B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528037A1 (en) * 1982-06-08 1983-12-09 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF PHENOLAMIDES
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1233877B (en) * 1961-07-25 1967-02-09 Ile De France Process for the preparation of substituted N- (tert. Aminoalkyl) -benzamides

Also Published As

Publication number Publication date
GB1395132A (en) 1975-05-21
IL42546A0 (en) 1973-08-29
AT350045B (en) 1979-05-10
MC1008A1 (en) 1974-10-18
KR780000254B1 (en) 1978-07-06
IE37822B1 (en) 1977-10-26
AU5721373A (en) 1975-01-09
LU67829A1 (en) 1974-07-10
DE2331262A1 (en) 1974-01-17
YU36692B (en) 1984-08-31
CA992559A (en) 1976-07-06
FR2281353A1 (en) 1976-03-05
FR2281353B1 (en) 1979-03-30
DD108283A5 (en) 1974-09-12
IE37822L (en) 1973-12-22
CH570971A5 (en) 1975-12-31
BE801037A (en) 1973-12-18
IL42546A (en) 1976-11-30
BG21398A3 (en) 1976-05-20
HU166935B (en) 1975-06-28
ATA536973A (en) 1978-10-15
AU468922B2 (en) 1976-01-29
ZA734193B (en) 1974-06-26
YU169373A (en) 1982-06-18
CS168034B2 (en) 1976-05-28

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