ES423781A1 - N-1-ethyl-2-pyrrolidinylmethyl-2-methoxy-5-sulphamoylbenzamide - Google Patents

N-1-ethyl-2-pyrrolidinylmethyl-2-methoxy-5-sulphamoylbenzamide

Info

Publication number
ES423781A1
ES423781A1 ES423781A ES423781A ES423781A1 ES 423781 A1 ES423781 A1 ES 423781A1 ES 423781 A ES423781 A ES 423781A ES 423781 A ES423781 A ES 423781A ES 423781 A1 ES423781 A1 ES 423781A1
Authority
ES
Spain
Prior art keywords
methoxy
ethyl
pyrrolidylmethyl
sulfamidobenzamide
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423781A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES423781A1 publication Critical patent/ES423781A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Preparation process for N- (1-ethyl-2-pyrrolidylmethyl) -2-methoxy-5-sulfamidobenzamide that responds to the formula: **(See formula)** its addition salts with pharmaceutically acceptable mineral or organic acids, and its quaternary ammonium salts; said procedure consisting of starting from 2-methoxy-5-sulfamidobenzoic acid, treating it with phosphorous pentachloride and ammonia so that 2-methoxy-5-sulfamidobenzonitrile is obtained, which is treated with methanol giving 2-methoxy-5- methyl sulfamidoiminobenzoate, from which methyl 2-methoxy-5-sulfamoylthiobenzoate is obtained by reacting with the magnesium of N-ethyl-% alpha; -aminoraethylpyrrolidine to give the N- (l -ethyl-2-pyrrolidylmethyl) -2-methoxy-5-sulfamidothiobenzamide and react the latter with lead acetate to obtain N- (l-ethyl-2-pyrrolidylmethyl) -2-methoxy-5-sulfamidobenzamide. (Machine-translation by Google Translate, not legally binding)
ES423781A 1973-03-06 1974-03-01 N-1-ethyl-2-pyrrolidinylmethyl-2-methoxy-5-sulphamoylbenzamide Expired ES423781A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7308033A FR2220522B1 (en) 1973-03-06 1973-03-06

Publications (1)

Publication Number Publication Date
ES423781A1 true ES423781A1 (en) 1976-05-01

Family

ID=9115878

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423781A Expired ES423781A1 (en) 1973-03-06 1974-03-01 N-1-ethyl-2-pyrrolidinylmethyl-2-methoxy-5-sulphamoylbenzamide

Country Status (10)

Country Link
JP (1) JPS5641631B2 (en)
AR (1) AR200304A1 (en)
AT (1) AT358567B (en)
CA (1) CA1010046A (en)
DE (1) DE2409891A1 (en)
ES (1) ES423781A1 (en)
FI (1) FI57931C (en)
FR (1) FR2220522B1 (en)
GB (1) GB1420890A (en)
IE (1) IE38949B1 (en)

Also Published As

Publication number Publication date
JPS5641631B2 (en) 1981-09-29
ATA159074A (en) 1980-02-15
IE38949B1 (en) 1978-07-05
IE38949L (en) 1974-09-06
AT358567B (en) 1980-09-25
CA1010046A (en) 1977-05-10
GB1420890A (en) 1976-01-14
DE2409891A1 (en) 1974-09-12
AR200304A1 (en) 1974-10-31
FR2220522A1 (en) 1974-10-04
FI57931C (en) 1980-11-10
FR2220522B1 (en) 1977-02-04
FI57931B (en) 1980-07-31
JPS49124056A (en) 1974-11-27

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