IE37822B1 - Preparation of benzamide derivatives - Google Patents
Preparation of benzamide derivativesInfo
- Publication number
- IE37822B1 IE37822B1 IE1006/73A IE100673A IE37822B1 IE 37822 B1 IE37822 B1 IE 37822B1 IE 1006/73 A IE1006/73 A IE 1006/73A IE 100673 A IE100673 A IE 100673A IE 37822 B1 IE37822 B1 IE 37822B1
- Authority
- IE
- Ireland
- Prior art keywords
- methoxy
- chlorobenzamide
- acetamido
- diethylamino
- june
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Abstract
1395132 N - [2 - (N,N - diethylamino)ethyl]- 2 - methoxy - 4 - amino - 5 - chlorobenzamide SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE 13 June 1973 [22 June 1972] 28204/73 Heading C2C N - [2 - (N<SP>1</SP>,N<SP>1</SP> - diethylamino)ethyl] - 2- methoxy - 4 - amino - 5 - chlorobenzamide is prepared by reacting a 2-methoxy-4-acetamido- 5-chlorobenzoyl halide with 2-chloroethylamine and reacting the resulting N-(2-chloroethyl) - 2 - methoxy - 4 - acetamido - 5 - chlorobenzamide with diethylamine, followed by alkaline hydrolysis, and may be converted to its pharmaceutically acceptable mineral or organic acid addition salts and its quaternary ammonium salts.
[GB1395132A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222695A FR2281353A1 (en) | 1972-06-22 | 1972-06-22 | NEW PROCESS FOR THE PREPARATION OF N (DIETHYLAMINOETHYL) 2-METHOXY 4-AMINO 5-CHLOROBENZAMIDE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37822L IE37822L (en) | 1973-12-22 |
| IE37822B1 true IE37822B1 (en) | 1977-10-26 |
Family
ID=9100674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1006/73A IE37822B1 (en) | 1972-06-22 | 1973-06-19 | Preparation of benzamide derivatives |
Country Status (20)
| Country | Link |
|---|---|
| KR (1) | KR780000254B1 (en) |
| AT (1) | AT350045B (en) |
| AU (1) | AU468922B2 (en) |
| BE (1) | BE801037A (en) |
| BG (1) | BG21398A3 (en) |
| CA (1) | CA992559A (en) |
| CH (1) | CH570971A5 (en) |
| CS (1) | CS168034B2 (en) |
| DD (1) | DD108283A5 (en) |
| DE (1) | DE2331262A1 (en) |
| ES (1) | ES416099A1 (en) |
| FR (1) | FR2281353A1 (en) |
| GB (1) | GB1395132A (en) |
| HU (1) | HU166935B (en) |
| IE (1) | IE37822B1 (en) |
| IL (1) | IL42546A (en) |
| LU (1) | LU67829A1 (en) |
| MC (1) | MC1008A1 (en) |
| YU (1) | YU36692B (en) |
| ZA (1) | ZA734193B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2528037A1 (en) * | 1982-06-08 | 1983-12-09 | Centre Nat Rech Scient | PROCESS FOR THE PREPARATION OF PHENOLAMIDES |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1233877B (en) * | 1961-07-25 | 1967-02-09 | Ile De France | Process for the preparation of substituted N- (tert. Aminoalkyl) -benzamides |
-
1972
- 1972-06-22 FR FR7222695A patent/FR2281353A1/en active Granted
-
1973
- 1973-06-08 MC MC1049A patent/MC1008A1/en unknown
- 1973-06-13 GB GB2820473A patent/GB1395132A/en not_active Expired
- 1973-06-18 HU HUSO1087A patent/HU166935B/hu unknown
- 1973-06-18 BG BG23904A patent/BG21398A3/xx unknown
- 1973-06-18 BE BE1005165A patent/BE801037A/en not_active IP Right Cessation
- 1973-06-19 DE DE2331262A patent/DE2331262A1/en active Pending
- 1973-06-19 IE IE1006/73A patent/IE37822B1/en unknown
- 1973-06-19 CA CA174,389A patent/CA992559A/en not_active Expired
- 1973-06-19 AT AT536973A patent/AT350045B/en not_active IP Right Cessation
- 1973-06-19 CS CS4411A patent/CS168034B2/cs unknown
- 1973-06-19 IL IL42546A patent/IL42546A/en unknown
- 1973-06-20 LU LU67829A patent/LU67829A1/xx unknown
- 1973-06-20 ES ES416099A patent/ES416099A1/en not_active Expired
- 1973-06-20 KR KR7300972A patent/KR780000254B1/en active
- 1973-06-20 DD DD171686A patent/DD108283A5/xx unknown
- 1973-06-21 ZA ZA734193A patent/ZA734193B/en unknown
- 1973-06-21 AU AU57213/73A patent/AU468922B2/en not_active Expired
- 1973-06-21 CH CH906473A patent/CH570971A5/xx not_active IP Right Cessation
- 1973-06-22 YU YU1693/73A patent/YU36692B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR780000254B1 (en) | 1978-07-06 |
| MC1008A1 (en) | 1974-10-18 |
| AT350045B (en) | 1979-05-10 |
| AU5721373A (en) | 1975-01-09 |
| YU169373A (en) | 1982-06-18 |
| DE2331262A1 (en) | 1974-01-17 |
| CS168034B2 (en) | 1976-05-28 |
| ATA536973A (en) | 1978-10-15 |
| BE801037A (en) | 1973-12-18 |
| IL42546A0 (en) | 1973-08-29 |
| AU468922B2 (en) | 1976-01-29 |
| ES416099A1 (en) | 1976-02-16 |
| FR2281353B1 (en) | 1979-03-30 |
| CH570971A5 (en) | 1975-12-31 |
| FR2281353A1 (en) | 1976-03-05 |
| BG21398A3 (en) | 1976-05-20 |
| YU36692B (en) | 1984-08-31 |
| IE37822L (en) | 1973-12-22 |
| GB1395132A (en) | 1975-05-21 |
| IL42546A (en) | 1976-11-30 |
| DD108283A5 (en) | 1974-09-12 |
| LU67829A1 (en) | 1974-07-10 |
| CA992559A (en) | 1976-07-06 |
| HU166935B (en) | 1975-06-28 |
| ZA734193B (en) | 1974-06-26 |
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