IL41662A - Cis and trans n1-piperonyl-n4-farnesyl-piperazine its preparation and pharmaceutical compositions containing it - Google Patents

Cis and trans n1-piperonyl-n4-farnesyl-piperazine its preparation and pharmaceutical compositions containing it

Info

Publication number
IL41662A
IL41662A IL41662A IL4166273A IL41662A IL 41662 A IL41662 A IL 41662A IL 41662 A IL41662 A IL 41662A IL 4166273 A IL4166273 A IL 4166273A IL 41662 A IL41662 A IL 41662A
Authority
IL
Israel
Prior art keywords
isomers
trans
mixture
compound
cis
Prior art date
Application number
IL41662A
Other languages
English (en)
Other versions
IL41662A0 (en
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of IL41662A0 publication Critical patent/IL41662A0/xx
Publication of IL41662A publication Critical patent/IL41662A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL41662A 1972-02-29 1973-02-28 Cis and trans n1-piperonyl-n4-farnesyl-piperazine its preparation and pharmaceutical compositions containing it IL41662A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB934872A GB1387324A (en) 1972-02-29 1972-02-29 Nitrogen containing isoprenoid compounds

Publications (2)

Publication Number Publication Date
IL41662A0 IL41662A0 (en) 1973-05-31
IL41662A true IL41662A (en) 1977-10-31

Family

ID=9870216

Family Applications (1)

Application Number Title Priority Date Filing Date
IL41662A IL41662A (en) 1972-02-29 1973-02-28 Cis and trans n1-piperonyl-n4-farnesyl-piperazine its preparation and pharmaceutical compositions containing it

Country Status (31)

Country Link
JP (1) JPS5335078B2 (cs)
AR (1) AR198301A1 (cs)
AT (1) AT333285B (cs)
AU (1) AU474791B2 (cs)
BE (1) BE796036A (cs)
BR (1) BR7301392D0 (cs)
CA (1) CA992084A (cs)
CH (1) CH569010A5 (cs)
CS (2) CS179411B2 (cs)
CY (1) CY867A (cs)
DE (1) DE2310044A1 (cs)
DK (1) DK144012C (cs)
ES (1) ES411984A1 (cs)
FI (1) FI56178C (cs)
FR (1) FR2181757B1 (cs)
GB (1) GB1387324A (cs)
HK (1) HK51476A (cs)
HU (1) HU165112B (cs)
IE (1) IE37317B1 (cs)
IL (1) IL41662A (cs)
IN (1) IN138638B (cs)
KE (1) KE2650A (cs)
MX (1) MX3448E (cs)
MY (1) MY7600279A (cs)
NL (1) NL7302525A (cs)
NO (1) NO137388C (cs)
PL (1) PL92977B1 (cs)
RO (2) RO76582A (cs)
SE (1) SE397978B (cs)
YU (1) YU35366B (cs)
ZA (1) ZA731182B (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2062940B1 (es) * 1993-03-11 1995-06-16 Vita Invest Sa Agente gastrocinetico, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Also Published As

Publication number Publication date
SE397978B (sv) 1977-11-28
NO137388B (no) 1977-11-14
JPS5335078B2 (cs) 1978-09-25
ZA731182B (en) 1974-11-27
IE37317L (en) 1973-08-29
MX3448E (es) 1980-12-02
YU49973A (en) 1980-06-30
CA992084A (en) 1976-06-29
HK51476A (en) 1976-08-20
RO71992A (ro) 1982-09-09
JPS4892385A (cs) 1973-11-30
NO137388C (no) 1978-02-22
AR198301A1 (es) 1974-06-14
ES411984A1 (es) 1976-06-16
PL92977B1 (cs) 1977-04-30
FR2181757B1 (cs) 1976-12-31
IN138638B (cs) 1976-03-06
GB1387324A (en) 1975-03-12
YU35366B (en) 1980-12-31
DK144012B (da) 1981-11-16
HU165112B (cs) 1974-06-28
CY867A (en) 1976-12-17
DE2310044A1 (de) 1973-09-13
BR7301392D0 (pt) 1974-08-29
IE37317B1 (en) 1977-06-22
AU474791B2 (en) 1976-08-05
ATA178473A (de) 1976-03-15
KE2650A (en) 1976-07-30
DK144012C (da) 1982-04-26
AU5230973A (en) 1974-08-22
FI56178C (fi) 1979-12-10
CS179411B2 (en) 1977-10-31
RO76582A (ro) 1981-04-30
CH569010A5 (cs) 1975-11-14
NL7302525A (cs) 1973-08-31
FR2181757A1 (cs) 1973-12-07
BE796036A (fr) 1973-06-18
FI56178B (fi) 1979-08-31
AT333285B (de) 1976-11-10
CS179450B2 (en) 1977-10-31
IL41662A0 (en) 1973-05-31
MY7600279A (en) 1976-12-31

Similar Documents

Publication Publication Date Title
US3123646A (en) Primary acyclic amines
US3405134A (en) Quinuclidyl esters of aromatic acids
HU186760B (en) Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
US20220259233A1 (en) Cannabinoid derivatives
GB1511463A (en) 1-acylamino methyl-1,2,3,4-tetrahydroisoquinolines
US3953453A (en) Trifluoromethyl substituted analogs of quinine and quinidine
US3875163A (en) Nitrogen containing acyclic isoprenoid compounds
IL41662A (en) Cis and trans n1-piperonyl-n4-farnesyl-piperazine its preparation and pharmaceutical compositions containing it
US3925393A (en) Novel salts of vincanol
JPS594434B2 (ja) チアプロスタグランジンユウドウタイオヨビソノセイゾウホウホウ
US4138407A (en) 2,4 Pyrrolidinediones
US3923986A (en) Nitrogen containing acyclic isoprenoid compounds in pharmaceutical compositions
US4059602A (en) 8-Methyl-, phenyl-, or substituted phenyl-11,12-secoprostaglandins
US3920672A (en) Thiacycl (2.2.2.)azine carboxylic acids
US2905590A (en) Thioxanthene derivative
US3687936A (en) 11-AMINOALIPHATIC-5:10-METHANODIBENZO {8 a:d{9 {0 {8 1:4{9 {0 CYCLOHEPTADIENES AND THE SALTS THEREOF
US4032656A (en) Aromatic prostaglandin derivatives
US3322778A (en) Novel ether derivatives of benzmorphans
US4033978A (en) Thiacycl[2.2.2]azine carboxylic acids
GB2102812A (en) Therapeutically active compounds from species of rubia synthetic derivatives thereof, methods for the production thereof and pharmaceutical compositions comprising the same
US3032556A (en) Process for the preparation of new
US3121722A (en) Process for preparing n-alkyl and n-hy-
Vidal Reaction of ethylene dibromide with triethylamine and the restoring action of some alkanebis (triethylammonium) ions upon sodium-deficient nerve fibers
US4005073A (en) 6-Acyl derivatives of aminopenicillanic acid
US3741974A (en) Substituted terphenyls