MX3448E - Procedimiento para preparar n1-piperonil-n4-3,7,11-trimetil-2,6,10-dodecatrienilpiperazina - Google Patents

Procedimiento para preparar n1-piperonil-n4-3,7,11-trimetil-2,6,10-dodecatrienilpiperazina

Info

Publication number
MX3448E
MX3448E MX004906U MX490673U MX3448E MX 3448 E MX3448 E MX 3448E MX 004906 U MX004906 U MX 004906U MX 490673 U MX490673 U MX 490673U MX 3448 E MX3448 E MX 3448E
Authority
MX
Mexico
Prior art keywords
trimethyl
formula
dodecatrienilpiperazina
piperonil
trimetil
Prior art date
Application number
MX004906U
Other languages
English (en)
Inventor
Silvia Tricerri Zumin
Mario Riva
Giuseppe Iafolla
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of MX3448E publication Critical patent/MX3448E/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26Sulfur atoms

Abstract

La presente invención se refiere a un procedimiento para preparar N1-piperonil-N4-3,7,11-trimetil-2,6,10-dodecatrienilpiperazina y sus sales de adición no toxicas farmaceuticamente aceptables de la fórmula: (ver gaceta) en donde A significa 3,7,11-trimetil-2,6,10-dodecatrieno y R significa piperolino, caracterizado por que comprende hacer reaccionar halogenuro de piperolino de la fórmula: (ver gaceta) en donde Hal significa bromo o cloro y R tienen el significado antes mencionado, y 3,7,11-trimetil-2,6,10-dodecatrienilpiperazina de la fórmula: (ver gaceta) en donde A tiene el significado antes mencionado, en presencia de benceno y a una temperatura de 0°C.
MX004906U 1972-02-29 1973-02-15 Procedimiento para preparar n1-piperonil-n4-3,7,11-trimetil-2,6,10-dodecatrienilpiperazina MX3448E (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB934872A GB1387324A (en) 1972-02-29 1972-02-29 Nitrogen containing isoprenoid compounds

Publications (1)

Publication Number Publication Date
MX3448E true MX3448E (es) 1980-12-02

Family

ID=9870216

Family Applications (1)

Application Number Title Priority Date Filing Date
MX004906U MX3448E (es) 1972-02-29 1973-02-15 Procedimiento para preparar n1-piperonil-n4-3,7,11-trimetil-2,6,10-dodecatrienilpiperazina

Country Status (31)

Country Link
JP (1) JPS5335078B2 (es)
AR (1) AR198301A1 (es)
AT (1) AT333285B (es)
AU (1) AU474791B2 (es)
BE (1) BE796036A (es)
BR (1) BR7301392D0 (es)
CA (1) CA992084A (es)
CH (1) CH569010A5 (es)
CS (2) CS179450B2 (es)
CY (1) CY867A (es)
DE (1) DE2310044A1 (es)
DK (1) DK144012C (es)
ES (1) ES411984A1 (es)
FI (1) FI56178C (es)
FR (1) FR2181757B1 (es)
GB (1) GB1387324A (es)
HK (1) HK51476A (es)
HU (1) HU165112B (es)
IE (1) IE37317B1 (es)
IL (1) IL41662A (es)
IN (1) IN138638B (es)
KE (1) KE2650A (es)
MX (1) MX3448E (es)
MY (1) MY7600279A (es)
NL (1) NL7302525A (es)
NO (1) NO137388C (es)
PL (1) PL92977B1 (es)
RO (2) RO71992A (es)
SE (1) SE397978B (es)
YU (1) YU35366B (es)
ZA (1) ZA731182B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2062940B1 (es) * 1993-03-11 1995-06-16 Vita Invest Sa Agente gastrocinetico, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Also Published As

Publication number Publication date
IL41662A (en) 1977-10-31
HU165112B (es) 1974-06-28
IL41662A0 (en) 1973-05-31
NO137388B (no) 1977-11-14
GB1387324A (en) 1975-03-12
YU49973A (en) 1980-06-30
SE397978B (sv) 1977-11-28
ATA178473A (de) 1976-03-15
JPS4892385A (es) 1973-11-30
FI56178C (fi) 1979-12-10
AU474791B2 (en) 1976-08-05
RO76582A (ro) 1981-04-30
DK144012B (da) 1981-11-16
FI56178B (fi) 1979-08-31
NO137388C (no) 1978-02-22
DE2310044A1 (de) 1973-09-13
AR198301A1 (es) 1974-06-14
JPS5335078B2 (es) 1978-09-25
CS179450B2 (en) 1977-10-31
CS179411B2 (en) 1977-10-31
KE2650A (en) 1976-07-30
MY7600279A (en) 1976-12-31
CH569010A5 (es) 1975-11-14
AU5230973A (en) 1974-08-22
PL92977B1 (es) 1977-04-30
BE796036A (fr) 1973-06-18
CY867A (en) 1976-12-17
IE37317L (en) 1973-08-29
BR7301392D0 (pt) 1974-08-29
IN138638B (es) 1976-03-06
AT333285B (de) 1976-11-10
IE37317B1 (en) 1977-06-22
FR2181757A1 (es) 1973-12-07
ES411984A1 (es) 1976-06-16
FR2181757B1 (es) 1976-12-31
HK51476A (en) 1976-08-20
YU35366B (en) 1980-12-31
ZA731182B (en) 1974-11-27
NL7302525A (es) 1973-08-31
RO71992A (ro) 1982-09-09
DK144012C (da) 1982-04-26
CA992084A (en) 1976-06-29

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