IE37317L - Heterocyclic substituted isoprenoid compounds - Google Patents

Heterocyclic substituted isoprenoid compounds

Info

Publication number
IE37317L
IE37317L IE730284A IE28473A IE37317L IE 37317 L IE37317 L IE 37317L IE 730284 A IE730284 A IE 730284A IE 28473 A IE28473 A IE 28473A IE 37317 L IE37317 L IE 37317L
Authority
IE
Ireland
Prior art keywords
trimethyldodecatrienyl
benzo
feb
compound
heterocyclic substituted
Prior art date
Application number
IE730284A
Other versions
IE37317B1 (en
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of IE37317L publication Critical patent/IE37317L/en
Publication of IE37317B1 publication Critical patent/IE37317B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26Sulfur atoms

Abstract

1387324 Derivative of 1-trimethyldodecatrienylpiperazine PIERREL SPA 21 Feb 1973 [29 Feb 1972] 9348/72 Heading C2C The invention comprises the compound of formula including the stereoisomers, and their pharmaceutically acceptable acid addition salts. In examples, their preparation is effected by reacting either (1) the trimethyldodecatrienyl bromide with 1-(benzo-1,3-dioxal-5-yl)methylpiperazine, or (2) 1-(trimethyldodecatrienyl)piperazine (II) with 1-(benzo-1,3-dioxol-5-yl)methyl chloride. Also prepared are the N-formyl and N-p-tosyl derivatives of II. Therapeutic compositions for oral or parenteral administration comprise the compound of the above formula, which has analgesic and antiinflammatory activity, spasmolytic action of the papaverinic type, and anti-gastric secretion and anti-ulcer activity but with absence of anti-cholinergic properties. [GB1387324A]
IE284/73A 1972-02-29 1973-02-23 Nitrogen containing isoprenoid compounds IE37317B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB934872A GB1387324A (en) 1972-02-29 1972-02-29 Nitrogen containing isoprenoid compounds

Publications (2)

Publication Number Publication Date
IE37317L true IE37317L (en) 1973-08-29
IE37317B1 IE37317B1 (en) 1977-06-22

Family

ID=9870216

Family Applications (1)

Application Number Title Priority Date Filing Date
IE284/73A IE37317B1 (en) 1972-02-29 1973-02-23 Nitrogen containing isoprenoid compounds

Country Status (31)

Country Link
JP (1) JPS5335078B2 (en)
AR (1) AR198301A1 (en)
AT (1) AT333285B (en)
AU (1) AU474791B2 (en)
BE (1) BE796036A (en)
BR (1) BR7301392D0 (en)
CA (1) CA992084A (en)
CH (1) CH569010A5 (en)
CS (2) CS179450B2 (en)
CY (1) CY867A (en)
DE (1) DE2310044A1 (en)
DK (1) DK144012C (en)
ES (1) ES411984A1 (en)
FI (1) FI56178C (en)
FR (1) FR2181757B1 (en)
GB (1) GB1387324A (en)
HK (1) HK51476A (en)
HU (1) HU165112B (en)
IE (1) IE37317B1 (en)
IL (1) IL41662A (en)
IN (1) IN138638B (en)
KE (1) KE2650A (en)
MX (1) MX3448E (en)
MY (1) MY7600279A (en)
NL (1) NL7302525A (en)
NO (1) NO137388C (en)
PL (1) PL92977B1 (en)
RO (2) RO71992A (en)
SE (1) SE397978B (en)
YU (1) YU35366B (en)
ZA (1) ZA731182B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2062940B1 (en) * 1993-03-11 1995-06-16 Vita Invest Sa GASTROCINETIC AGENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT.

Also Published As

Publication number Publication date
NO137388B (en) 1977-11-14
IN138638B (en) 1976-03-06
ATA178473A (en) 1976-03-15
AT333285B (en) 1976-11-10
FR2181757A1 (en) 1973-12-07
CA992084A (en) 1976-06-29
YU49973A (en) 1980-06-30
MY7600279A (en) 1976-12-31
IL41662A0 (en) 1973-05-31
AR198301A1 (en) 1974-06-14
HK51476A (en) 1976-08-20
HU165112B (en) 1974-06-28
JPS4892385A (en) 1973-11-30
AU474791B2 (en) 1976-08-05
DK144012B (en) 1981-11-16
CS179411B2 (en) 1977-10-31
PL92977B1 (en) 1977-04-30
MX3448E (en) 1980-12-02
ES411984A1 (en) 1976-06-16
RO76582A (en) 1981-04-30
CH569010A5 (en) 1975-11-14
FR2181757B1 (en) 1976-12-31
GB1387324A (en) 1975-03-12
JPS5335078B2 (en) 1978-09-25
YU35366B (en) 1980-12-31
BR7301392D0 (en) 1974-08-29
FI56178C (en) 1979-12-10
BE796036A (en) 1973-06-18
CY867A (en) 1976-12-17
RO71992A (en) 1982-09-09
NO137388C (en) 1978-02-22
SE397978B (en) 1977-11-28
DE2310044A1 (en) 1973-09-13
IE37317B1 (en) 1977-06-22
CS179450B2 (en) 1977-10-31
AU5230973A (en) 1974-08-22
FI56178B (en) 1979-08-31
NL7302525A (en) 1973-08-31
KE2650A (en) 1976-07-30
ZA731182B (en) 1974-11-27
DK144012C (en) 1982-04-26
IL41662A (en) 1977-10-31

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