IE37317L - Heterocyclic substituted isoprenoid compounds - Google Patents
Heterocyclic substituted isoprenoid compoundsInfo
- Publication number
- IE37317L IE37317L IE730284A IE28473A IE37317L IE 37317 L IE37317 L IE 37317L IE 730284 A IE730284 A IE 730284A IE 28473 A IE28473 A IE 28473A IE 37317 L IE37317 L IE 37317L
- Authority
- IE
- Ireland
- Prior art keywords
- trimethyldodecatrienyl
- benzo
- feb
- compound
- heterocyclic substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
1387324 Derivative of 1-trimethyldodecatrienylpiperazine PIERREL SPA 21 Feb 1973 [29 Feb 1972] 9348/72 Heading C2C The invention comprises the compound of formula including the stereoisomers, and their pharmaceutically acceptable acid addition salts. In examples, their preparation is effected by reacting either (1) the trimethyldodecatrienyl bromide with 1-(benzo-1,3-dioxal-5-yl)methylpiperazine, or (2) 1-(trimethyldodecatrienyl)piperazine (II) with 1-(benzo-1,3-dioxol-5-yl)methyl chloride. Also prepared are the N-formyl and N-p-tosyl derivatives of II. Therapeutic compositions for oral or parenteral administration comprise the compound of the above formula, which has analgesic and antiinflammatory activity, spasmolytic action of the papaverinic type, and anti-gastric secretion and anti-ulcer activity but with absence of anti-cholinergic properties.
[GB1387324A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB934872A GB1387324A (en) | 1972-02-29 | 1972-02-29 | Nitrogen containing isoprenoid compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IE37317L true IE37317L (en) | 1973-08-29 |
IE37317B1 IE37317B1 (en) | 1977-06-22 |
Family
ID=9870216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE284/73A IE37317B1 (en) | 1972-02-29 | 1973-02-23 | Nitrogen containing isoprenoid compounds |
Country Status (31)
Country | Link |
---|---|
JP (1) | JPS5335078B2 (en) |
AR (1) | AR198301A1 (en) |
AT (1) | AT333285B (en) |
AU (1) | AU474791B2 (en) |
BE (1) | BE796036A (en) |
BR (1) | BR7301392D0 (en) |
CA (1) | CA992084A (en) |
CH (1) | CH569010A5 (en) |
CS (2) | CS179450B2 (en) |
CY (1) | CY867A (en) |
DE (1) | DE2310044A1 (en) |
DK (1) | DK144012C (en) |
ES (1) | ES411984A1 (en) |
FI (1) | FI56178C (en) |
FR (1) | FR2181757B1 (en) |
GB (1) | GB1387324A (en) |
HK (1) | HK51476A (en) |
HU (1) | HU165112B (en) |
IE (1) | IE37317B1 (en) |
IL (1) | IL41662A (en) |
IN (1) | IN138638B (en) |
KE (1) | KE2650A (en) |
MX (1) | MX3448E (en) |
MY (1) | MY7600279A (en) |
NL (1) | NL7302525A (en) |
NO (1) | NO137388C (en) |
PL (1) | PL92977B1 (en) |
RO (2) | RO76582A (en) |
SE (1) | SE397978B (en) |
YU (1) | YU35366B (en) |
ZA (1) | ZA731182B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2062940B1 (en) * | 1993-03-11 | 1995-06-16 | Vita Invest Sa | GASTROCINETIC AGENT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT. |
-
1972
- 1972-02-29 GB GB934872A patent/GB1387324A/en not_active Expired
-
1973
- 1973-02-15 MX MX004906U patent/MX3448E/en unknown
- 1973-02-19 AU AU52309/73A patent/AU474791B2/en not_active Expired
- 1973-02-20 FI FI506/73A patent/FI56178C/en active
- 1973-02-20 ZA ZA731182A patent/ZA731182B/en unknown
- 1973-02-20 AR AR246682A patent/AR198301A1/en active
- 1973-02-20 IN IN385/CAL/73A patent/IN138638B/en unknown
- 1973-02-21 CY CY867A patent/CY867A/en unknown
- 1973-02-22 FR FR7306245A patent/FR2181757B1/fr not_active Expired
- 1973-02-23 IE IE284/73A patent/IE37317B1/en unknown
- 1973-02-23 ES ES411984A patent/ES411984A1/en not_active Expired
- 1973-02-23 NL NL7302525A patent/NL7302525A/xx not_active Application Discontinuation
- 1973-02-24 CS CS7600002329A patent/CS179450B2/en unknown
- 1973-02-24 CS CS7300001348A patent/CS179411B2/en unknown
- 1973-02-26 BR BR731392A patent/BR7301392D0/en unknown
- 1973-02-27 NO NO800/73A patent/NO137388C/en unknown
- 1973-02-27 HU HUPI378A patent/HU165112B/hu unknown
- 1973-02-27 YU YU499/73A patent/YU35366B/en unknown
- 1973-02-27 CH CH281773A patent/CH569010A5/xx not_active IP Right Cessation
- 1973-02-27 DK DK103873A patent/DK144012C/en active
- 1973-02-27 CA CA164,748A patent/CA992084A/en not_active Expired
- 1973-02-27 BE BE128167A patent/BE796036A/en not_active IP Right Cessation
- 1973-02-27 SE SE7302708A patent/SE397978B/en unknown
- 1973-02-28 JP JP2420373A patent/JPS5335078B2/ja not_active Expired
- 1973-02-28 RO RO7382295A patent/RO76582A/en unknown
- 1973-02-28 RO RO7374009A patent/RO71992A/en unknown
- 1973-02-28 DE DE19732310044 patent/DE2310044A1/en not_active Ceased
- 1973-02-28 AT AT178473A patent/AT333285B/en not_active IP Right Cessation
- 1973-02-28 IL IL41662A patent/IL41662A/en unknown
- 1973-02-28 PL PL1973160969A patent/PL92977B1/pl unknown
-
1976
- 1976-07-19 KE KE2650*UA patent/KE2650A/en unknown
- 1976-08-12 HK HK514/76*UA patent/HK51476A/en unknown
- 1976-12-31 MY MY1976279A patent/MY7600279A/en unknown
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