IL41615A - Insulin derivatives,their production and pharmaceutical compositions containing them - Google Patents
Insulin derivatives,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL41615A IL41615A IL41615A IL4161573A IL41615A IL 41615 A IL41615 A IL 41615A IL 41615 A IL41615 A IL 41615A IL 4161573 A IL4161573 A IL 4161573A IL 41615 A IL41615 A IL 41615A
- Authority
- IL
- Israel
- Prior art keywords
- production
- pharmaceutical compositions
- compositions containing
- insulin derivatives
- insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722209835 DE2209835C3 (de) | 1972-03-01 | Insulinderivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41615A0 IL41615A0 (en) | 1973-04-30 |
| IL41615A true IL41615A (en) | 1975-12-31 |
Family
ID=5837578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41615A IL41615A (en) | 1972-03-01 | 1973-02-26 | Insulin derivatives,their production and pharmaceutical compositions containing them |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3907763A (OSRAM) |
| JP (1) | JPS4897889A (OSRAM) |
| AT (1) | AT333987B (OSRAM) |
| BE (1) | BE795997A (OSRAM) |
| CH (1) | CH579916A5 (OSRAM) |
| DK (1) | DK146623C (OSRAM) |
| FR (1) | FR2181778B1 (OSRAM) |
| GB (1) | GB1374385A (OSRAM) |
| IL (1) | IL41615A (OSRAM) |
| NL (1) | NL7302898A (OSRAM) |
| SE (1) | SE421690B (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2428412A1 (de) * | 1974-06-12 | 1976-01-15 | Hoechst Ag | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
| USRE32015E (en) * | 1974-06-12 | 1985-10-29 | Hoechst Aktiengesellschaft | Process for the manufacture of insulin, analogs and derivatives thereof |
| DE2439296A1 (de) * | 1974-08-16 | 1976-02-26 | Hoechst Ag | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
| US6869930B1 (en) * | 1993-09-17 | 2005-03-22 | Novo Nordisk A/S | Acylated insulin |
| SI0792290T1 (en) * | 1993-09-17 | 2001-12-31 | Novo Nordisk As | Acylated insulin |
| US20010041786A1 (en) * | 1995-06-07 | 2001-11-15 | Mark L. Brader | Stabilized acylated insulin formulations |
| US5898067A (en) * | 1997-02-07 | 1999-04-27 | Novo Nordisk A/S | Crystallization of proteins |
| JP2001521004A (ja) | 1997-10-24 | 2001-11-06 | イーライ・リリー・アンド・カンパニー | 脂肪酸−アシル化インスリン類似体 |
| CO4970787A1 (es) * | 1997-12-23 | 2000-11-07 | Lilly Co Eli | Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea |
| US6323311B1 (en) | 1999-09-22 | 2001-11-27 | University Of Utah Research Foundation | Synthesis of insulin derivatives |
| US8618049B2 (en) | 2009-09-08 | 2013-12-31 | Stephen B. H. Kent | Ester insulin |
| EP2576588A4 (en) * | 2010-05-25 | 2014-07-09 | Syngene Ltd | METHODS FOR SYNTHESIZING DICARBA BRIDGES CONTAINING ALKYNES IN PEPTIDES |
| WO1990007280A1 (en) * | 2010-07-13 | 1990-07-12 | Victor Manuel Pracas | Confectionery storage and dispensing device |
| PH12017500935A1 (en) | 2014-11-21 | 2017-11-27 | Merck Sharp & Dohme | Insulin receptor partial agonists |
| EP3448417B1 (en) | 2016-04-26 | 2025-11-12 | Merck Sharp & Dohme LLC | Insulin dimer-incretin conjugates |
| EP3922260A3 (en) | 2016-05-24 | 2022-06-15 | Merck Sharp & Dohme Corp. | Insulin receptor partial agonists and glp-1 analogues |
| EP3463413A4 (en) | 2016-05-25 | 2020-03-04 | Merck Sharp & Dohme Corp. | INSULIN RECEPTOR PART AGONISTS |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3679653A (en) * | 1968-09-27 | 1972-07-25 | Monsanto Co | Hormonally-active reaction product of a polymer with a hormone |
| IE36225B1 (en) * | 1971-01-28 | 1976-09-15 | Nat Res Dev | Improvements relating to insulin derivatives |
-
1973
- 1973-02-16 US US333361A patent/US3907763A/en not_active Expired - Lifetime
- 1973-02-26 IL IL41615A patent/IL41615A/xx unknown
- 1973-02-27 BE BE128128A patent/BE795997A/xx not_active IP Right Cessation
- 1973-02-27 CH CH284673A patent/CH579916A5/xx not_active IP Right Cessation
- 1973-02-27 JP JP48022747A patent/JPS4897889A/ja active Pending
- 1973-02-28 SE SE7302818A patent/SE421690B/xx unknown
- 1973-02-28 GB GB972673A patent/GB1374385A/en not_active Expired
- 1973-02-28 DK DK109173A patent/DK146623C/da not_active IP Right Cessation
- 1973-03-01 NL NL7302898A patent/NL7302898A/xx not_active Application Discontinuation
- 1973-03-01 AT AT184873A patent/AT333987B/de not_active IP Right Cessation
- 1973-03-01 FR FR7307334A patent/FR2181778B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7302898A (OSRAM) | 1973-09-04 |
| JPS4897889A (OSRAM) | 1973-12-13 |
| IL41615A0 (en) | 1973-04-30 |
| AT333987B (de) | 1976-12-27 |
| FR2181778B1 (OSRAM) | 1976-12-03 |
| DE2209835B2 (de) | 1976-04-29 |
| CH579916A5 (OSRAM) | 1976-09-30 |
| GB1374385A (en) | 1974-11-20 |
| SE421690B (sv) | 1982-01-25 |
| DK146623B (da) | 1983-11-21 |
| ATA184873A (de) | 1976-04-15 |
| DK146623C (da) | 1984-04-30 |
| DE2209835A1 (de) | 1973-09-06 |
| US3907763A (en) | 1975-09-23 |
| BE795997A (fr) | 1973-08-27 |
| FR2181778A1 (OSRAM) | 1973-12-07 |
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