DK146623C - Fremgangsmaade til fremstilling af bifunktionelt tvaerbundet insulin - Google Patents

Fremgangsmaade til fremstilling af bifunktionelt tvaerbundet insulin

Info

Publication number
DK146623C
DK146623C DK109173A DK109173A DK146623C DK 146623 C DK146623 C DK 146623C DK 109173 A DK109173 A DK 109173A DK 109173 A DK109173 A DK 109173A DK 146623 C DK146623 C DK 146623C
Authority
DK
Denmark
Prior art keywords
bifunctional
insulin
procedure
manufacturing
circuit
Prior art date
Application number
DK109173A
Other languages
English (en)
Other versions
DK146623B (da
Inventor
Dietrich Brandenburg
Walter Puls
Original Assignee
Deutsches Wollforschinst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722209835 external-priority patent/DE2209835C3/de
Application filed by Deutsches Wollforschinst filed Critical Deutsches Wollforschinst
Publication of DK146623B publication Critical patent/DK146623B/da
Application granted granted Critical
Publication of DK146623C publication Critical patent/DK146623C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK109173A 1972-03-01 1973-02-28 Fremgangsmaade til fremstilling af bifunktionelt tvaerbundet insulin DK146623C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2209835 1972-03-01
DE19722209835 DE2209835C3 (de) 1972-03-01 Insulinderivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
DK146623B DK146623B (da) 1983-11-21
DK146623C true DK146623C (da) 1984-04-30

Family

ID=5837578

Family Applications (1)

Application Number Title Priority Date Filing Date
DK109173A DK146623C (da) 1972-03-01 1973-02-28 Fremgangsmaade til fremstilling af bifunktionelt tvaerbundet insulin

Country Status (11)

Country Link
US (1) US3907763A (da)
JP (1) JPS4897889A (da)
AT (1) AT333987B (da)
BE (1) BE795997A (da)
CH (1) CH579916A5 (da)
DK (1) DK146623C (da)
FR (1) FR2181778B1 (da)
GB (1) GB1374385A (da)
IL (1) IL41615A (da)
NL (1) NL7302898A (da)
SE (1) SE421690B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32015E (en) * 1974-06-12 1985-10-29 Hoechst Aktiengesellschaft Process for the manufacture of insulin, analogs and derivatives thereof
DE2428412A1 (de) * 1974-06-12 1976-01-15 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
DE2439296A1 (de) * 1974-08-16 1976-02-26 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
US6869930B1 (en) * 1993-09-17 2005-03-22 Novo Nordisk A/S Acylated insulin
PL178466B1 (pl) * 1993-09-17 2000-05-31 Novo Nordisk As Pochodna insuliny i kompozycja farmaceutyczna do leczenia cukrzycy
US20010041786A1 (en) * 1995-06-07 2001-11-15 Mark L. Brader Stabilized acylated insulin formulations
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
HUP0004169A3 (en) 1997-10-24 2001-06-28 Lilly Co Eli Insoluble insulin compositions and process for production thereof
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
WO2011031662A1 (en) 2009-09-08 2011-03-17 Kent Stephen B H Ester insulin
EP2576612A4 (en) * 2010-05-25 2014-07-09 Syngene Ltd INSULIN ANALOG
WO1990007280A1 (en) * 2010-07-13 1990-07-12 Victor Manuel Pracas Confectionery storage and dispensing device
AU2015349890B2 (en) 2014-11-21 2018-08-30 Merck Sharp & Dohme Llc Insulin receptor partial agonists
WO2017189342A1 (en) 2016-04-26 2017-11-02 Merck Sharp & Dohme Corp. Insulin dimer-incretin conjugates
WO2017205191A1 (en) 2016-05-24 2017-11-30 Merck Sharp & Dohme Corp. Insulin receptor partial agonists and glp-1 analogues
US10689430B2 (en) 2016-05-25 2020-06-23 Merck Sharp & Dohme Corp. Insulin receptor partial agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679653A (en) * 1968-09-27 1972-07-25 Monsanto Co Hormonally-active reaction product of a polymer with a hormone
IE36225B1 (en) * 1971-01-28 1976-09-15 Nat Res Dev Improvements relating to insulin derivatives

Also Published As

Publication number Publication date
DE2209835A1 (de) 1973-09-06
FR2181778A1 (da) 1973-12-07
GB1374385A (en) 1974-11-20
US3907763A (en) 1975-09-23
FR2181778B1 (da) 1976-12-03
IL41615A (en) 1975-12-31
DE2209835B2 (de) 1976-04-29
ATA184873A (de) 1976-04-15
DK146623B (da) 1983-11-21
CH579916A5 (da) 1976-09-30
NL7302898A (da) 1973-09-04
SE421690B (sv) 1982-01-25
IL41615A0 (en) 1973-04-30
JPS4897889A (da) 1973-12-13
BE795997A (fr) 1973-08-27
AT333987B (de) 1976-12-27

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Legal Events

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PBP Patent lapsed