IL39982A - The isolation of antithrombin from animal material - Google Patents

The isolation of antithrombin from animal material

Info

Publication number
IL39982A
IL39982A IL39982A IL3998272A IL39982A IL 39982 A IL39982 A IL 39982A IL 39982 A IL39982 A IL 39982A IL 3998272 A IL3998272 A IL 3998272A IL 39982 A IL39982 A IL 39982A
Authority
IL
Israel
Prior art keywords
antithrombin
isolation
animal material
animal
Prior art date
Application number
IL39982A
Other languages
English (en)
Other versions
IL39982A0 (en
Original Assignee
Kabi Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Ab filed Critical Kabi Ab
Publication of IL39982A0 publication Critical patent/IL39982A0/xx
Publication of IL39982A publication Critical patent/IL39982A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL39982A 1971-09-08 1972-07-24 The isolation of antithrombin from animal material IL39982A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7111350A SE392038B (sv) 1971-09-08 1971-09-08 Forfarande for isolering av antitrombin ur blod eller blodprodukter

Publications (2)

Publication Number Publication Date
IL39982A0 IL39982A0 (en) 1972-09-28
IL39982A true IL39982A (en) 1974-11-29

Family

ID=20293800

Family Applications (1)

Application Number Title Priority Date Filing Date
IL39982A IL39982A (en) 1971-09-08 1972-07-24 The isolation of antithrombin from animal material

Country Status (22)

Country Link
US (1) US3842061A (fi)
JP (1) JPS5545528B2 (fi)
AT (1) AT324549B (fi)
AU (1) AU461865B2 (fi)
BE (1) BE787284A (fi)
CA (1) CA979805A (fi)
CH (1) CH577829A5 (fi)
CS (1) CS172957B2 (fi)
DE (1) DE2243688C3 (fi)
DK (1) DK131128B (fi)
ES (1) ES406199A1 (fi)
FI (1) FI50583C (fi)
FR (1) FR2154483B1 (fi)
GB (1) GB1356229A (fi)
HU (1) HU165070B (fi)
IE (1) IE36670B1 (fi)
IL (1) IL39982A (fi)
NL (1) NL154118B (fi)
NO (1) NO135302C (fi)
PL (1) PL83490B1 (fi)
SE (1) SE392038B (fi)
ZA (1) ZA726024B (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US4022758A (en) * 1973-06-19 1977-05-10 Ab Kabi Isolation of coagulation factors I and VIII from biological material
US4054557A (en) * 1974-05-15 1977-10-18 Ab Kabi Growth promoting polypeptides and preparation method
US4103685A (en) * 1976-01-05 1978-08-01 Lupien Paul J Method and apparatus for extravascular treatment of blood
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration
NZ187246A (en) * 1976-03-04 1980-05-27 New Zealand Dev Finance Hydrophilic hydroxy c2-c4 alkylated crosslinked regenerated cellulose
US4087415A (en) * 1976-06-09 1978-05-02 William L. Wilson Antithrombin III
JPS597693B2 (ja) * 1978-01-07 1984-02-20 株式会社ミドリ十字 抗トロンビン製剤及びその製法
DE2916711A1 (de) 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma
SE422081B (sv) * 1979-08-22 1982-02-15 Ird Biomaterial Ab Sett att pavisa proteolytiska enzymer
US4386025A (en) * 1980-09-30 1983-05-31 Cutter Laboratories, Inc. Method of preparing antithrombin
US4446314A (en) * 1980-09-30 1984-05-01 Cutter Laboratories, Inc. Fractionation of heparin
DE3038163A1 (de) * 1980-10-09 1982-05-06 Boehringer Mannheim Gmbh, 6800 Mannheim Thrombininhibitor, seine herstellung und verwendung
FR2527222A1 (fr) * 1982-05-19 1983-11-25 Christine Fougnot Procede de separation et de purification des proteases et des antiproteases de la coagulation sanguine, ainsi que du complexe protease/antiprotease
US4632981A (en) * 1982-07-30 1986-12-30 Genentech, Inc. Human antithrombin III
CA1221307A (en) * 1982-12-02 1987-05-05 Nobutaka Tani Adsorbent and process for preparing the same
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
AT379310B (de) * 1983-05-20 1985-12-27 Immuno Ag Verfahren zur herstellung eines antithrombin iii-heparin- bzw. antithrombin iii-heparinoidkonzentrates
AU571078B2 (en) * 1984-04-14 1988-03-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Purification of filamentous hemagglutinin
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
DE3519011A1 (de) * 1985-05-25 1986-11-27 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines materials zur affinitaetschromatographie
US4656254A (en) * 1985-12-02 1987-04-07 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor and antithrombin III
AT399095B (de) * 1986-03-27 1995-03-27 Vukovich Thomas Dr Verfahren zur auftrennung von proteinen mittels gradientenelution und vorrichtung zur durchführung des verfahrens
US4749783A (en) * 1986-07-11 1988-06-07 Miles Laboratories, Inc. Viral inactivation and purification of active proteins
CA1341379C (en) 1988-04-28 2002-07-23 Welfide Corporation Purified antithrombin-iii and methods of producing the same
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
US6562781B1 (en) 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6491965B1 (en) * 1995-11-30 2002-12-10 Hamilton Civic Hospitals Research Development, Inc. Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
US5989593A (en) * 1996-11-20 1999-11-23 Yoshitomi Pharmaceutical Industries, Ltd. Method for producing antithrombin-III, method for purifying it, and preparation containing it
AT405739B (de) 1997-09-19 1999-11-25 Immuno Ag Verfahren zur reinigung von antithrombin iii
US8563693B2 (en) * 2001-01-26 2013-10-22 Acceleration Biopharmaceuticals, Inc. Method of treating human immunodeficiency virus infection in a mammal comprising administering heparin-activated antithrombin III
ATE377657T1 (de) * 2001-01-26 2007-11-15 Gen Hospital Corp Serpin-arzneistoffe zur behandlung einer hiv- infektion und verfahren zu deren verwendung
SE0203770D0 (sv) * 2002-12-19 2002-12-19 Biovitrum Ab Method of separation
JP4970260B2 (ja) 2004-08-20 2012-07-04 プロメティック バイオサイエンシズ，リミテッド 親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE366760B (fi) * 1967-12-18 1974-05-06 J Sjoevall
DE1907738A1 (de) * 1969-02-15 1970-08-13 Bayer Ag Verfahren zur Abtrennung des Trypsin-Plasmin-Inhibitors vom Thrombin-Inhibitor in handelsueblichen Hirudinpraeparaten und in Hirudinrohpraeparaten

Also Published As

Publication number Publication date
US3842061A (en) 1974-10-15
NO135302C (fi) 1977-03-23
NO135302B (fi) 1976-12-13
ZA726024B (en) 1973-05-30
JPS4835017A (fi) 1973-05-23
DK131128C (fi) 1975-11-03
FR2154483B1 (fi) 1977-01-14
GB1356229A (en) 1974-06-12
FI50583B (fi) 1976-02-02
IE36670L (en) 1973-03-08
SU447876A3 (ru) 1974-10-25
SE392038B (sv) 1977-03-14
AT324549B (de) 1975-09-10
BE787284A (fr) 1972-12-01
JPS5545528B2 (fi) 1980-11-18
CA979805A (en) 1975-12-16
DE2243688C3 (de) 1984-05-10
FI50583C (fi) 1976-05-10
FR2154483A1 (fi) 1973-05-11
CS172957B2 (fi) 1977-01-28
NL154118B (nl) 1977-08-15
DE2243688A1 (de) 1973-03-22
AU461865B2 (en) 1975-06-05
CH577829A5 (fi) 1976-07-30
IE36670B1 (en) 1977-01-19
DK131128B (da) 1975-06-02
AU4637372A (en) 1974-03-14
IL39982A0 (en) 1972-09-28
NL7211953A (fi) 1973-03-12
ES406199A1 (es) 1975-07-01
DE2243688B2 (de) 1978-06-15
PL83490B1 (fi) 1975-12-31
HU165070B (fi) 1974-06-28

Similar Documents

Publication Publication Date Title
IL39982A0 (en) The isolation of antithrombin from animal material
IL39225A (en) Process for the manufacture of methyl substituted p-benzoquinones
ZA724456B (en) The control of packaging
YU223371A (en) Process for the isolation of fish proteins
GB1399160A (en) Process for the manufacture of polylauryl-lactam
JPS56108706A (en) Modification of fragrance
GB1372957A (en) Insecticidal compositions
JPS56135403A (en) Herbicidal composition
EG10580A (en) Malogeno-acetanilides as herbicides
ZA725365B (en) Agent for the control of plant-pathogenic organisms
ZA727738B (en) Process for the preparation of 4-chloro-2-dimethoxy-aniline
CH609065A5 (en) Process for the preparation of 21-adamantoyloxysteroids
IL40533A0 (en) The preparation of benzylpyrimidine
ZA729008B (en) Herbicidal composition
GB1401987A (en) Cyanoalkylamino-s-triazines as herbicides
KR780000132B1 (en) Process for the preparation of 2.6-dinitroaniline
IL38885A0 (en) Bactericidal substance
ZA727831B (en) Process for the preparation of methylcobalamine
GB1363818A (en) Photographic material for the production of equidensities
IL40180A (en) The production of beta-chloroethyltrichlorosilane
IL39211A0 (en) The use of 4-dialkylamino-phenylhydrazones as fungicides and certain such novel compounds
ZA722915B (en) Novel insecticides
HK26276A (en) Wall covering material
ZA712516B (en) Process for the preparation of propionaldehyde
ZA717402B (en) Process for the preparation of argininemalate