FI50583C - Menetelmä antitrombiinin eristämiseksi verestä tai verituotteista adso rboimalla sulfatoidulle polysakkaridille - Google Patents
Menetelmä antitrombiinin eristämiseksi verestä tai verituotteista adso rboimalla sulfatoidulle polysakkaridilleInfo
- Publication number
- FI50583C FI50583C FI722094A FI209472A FI50583C FI 50583 C FI50583 C FI 50583C FI 722094 A FI722094 A FI 722094A FI 209472 A FI209472 A FI 209472A FI 50583 C FI50583 C FI 50583C
- Authority
- FI
- Finland
- Prior art keywords
- blood
- antithrombin
- isolating
- adsorption
- sulphated polysaccharide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
- Y10S530/831—Cohn fractions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7111350A SE392038B (sv) | 1971-09-08 | 1971-09-08 | Forfarande for isolering av antitrombin ur blod eller blodprodukter |
Publications (2)
Publication Number | Publication Date |
---|---|
FI50583B FI50583B (fi) | 1976-02-02 |
FI50583C true FI50583C (fi) | 1976-05-10 |
Family
ID=20293800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI722094A FI50583C (fi) | 1971-09-08 | 1972-07-26 | Menetelmä antitrombiinin eristämiseksi verestä tai verituotteista adso rboimalla sulfatoidulle polysakkaridille |
Country Status (23)
Country | Link |
---|---|
US (1) | US3842061A (fi) |
JP (1) | JPS5545528B2 (fi) |
AT (1) | AT324549B (fi) |
AU (1) | AU461865B2 (fi) |
BE (1) | BE787284A (fi) |
CA (1) | CA979805A (fi) |
CH (1) | CH577829A5 (fi) |
CS (1) | CS172957B2 (fi) |
DE (1) | DE2243688C3 (fi) |
DK (1) | DK131128B (fi) |
ES (1) | ES406199A1 (fi) |
FI (1) | FI50583C (fi) |
FR (1) | FR2154483B1 (fi) |
GB (1) | GB1356229A (fi) |
HU (1) | HU165070B (fi) |
IE (1) | IE36670B1 (fi) |
IL (1) | IL39982A (fi) |
NL (1) | NL154118B (fi) |
NO (1) | NO135302C (fi) |
PL (1) | PL83490B1 (fi) |
SE (1) | SE392038B (fi) |
SU (1) | SU447876A3 (fi) |
ZA (1) | ZA726024B (fi) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4022758A (en) * | 1973-06-19 | 1977-05-10 | Ab Kabi | Isolation of coagulation factors I and VIII from biological material |
US3920625A (en) * | 1973-06-19 | 1975-11-18 | Kabi Ab | Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates |
US4054557A (en) * | 1974-05-15 | 1977-10-18 | Ab Kabi | Growth promoting polypeptides and preparation method |
US4103685A (en) * | 1976-01-05 | 1978-08-01 | Lupien Paul J | Method and apparatus for extravascular treatment of blood |
NZ180199A (en) * | 1976-03-04 | 1978-11-13 | New Zealand Dev Finance | Method of testing for the presence of elevated plasma liprotein concentration |
NZ180198A (en) * | 1976-03-04 | 1978-11-13 | New Zealand Dev Finance | Cationic ion exchanger with a cross-linked carbohydrate marix |
US4087415A (en) * | 1976-06-09 | 1978-05-02 | William L. Wilson | Antithrombin III |
JPS597693B2 (ja) * | 1978-01-07 | 1984-02-20 | 株式会社ミドリ十字 | 抗トロンビン製剤及びその製法 |
DE2916711A1 (de) | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
US4278594A (en) * | 1979-06-19 | 1981-07-14 | David Amrani | Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma |
US4210580A (en) * | 1979-06-19 | 1980-07-01 | David Amrani | Process for separation and isolation of AHF and fibronectin from blood plasma |
SE422081B (sv) * | 1979-08-22 | 1982-02-15 | Ird Biomaterial Ab | Sett att pavisa proteolytiska enzymer |
US4446314A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Fractionation of heparin |
US4386025A (en) * | 1980-09-30 | 1983-05-31 | Cutter Laboratories, Inc. | Method of preparing antithrombin |
DE3038163A1 (de) * | 1980-10-09 | 1982-05-06 | Boehringer Mannheim Gmbh, 6800 Mannheim | Thrombininhibitor, seine herstellung und verwendung |
FR2527222A1 (fr) * | 1982-05-19 | 1983-11-25 | Christine Fougnot | Procede de separation et de purification des proteases et des antiproteases de la coagulation sanguine, ainsi que du complexe protease/antiprotease |
US4632981A (en) * | 1982-07-30 | 1986-12-30 | Genentech, Inc. | Human antithrombin III |
CA1221307A (en) * | 1982-12-02 | 1987-05-05 | Nobutaka Tani | Adsorbent and process for preparing the same |
US4515714A (en) * | 1983-03-09 | 1985-05-07 | Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute | Method for purification of hepatitis B virus surface antigen |
AT379310B (de) * | 1983-05-20 | 1985-12-27 | Immuno Ag | Verfahren zur herstellung eines antithrombin iii-heparin- bzw. antithrombin iii-heparinoidkonzentrates |
AT379510B (de) * | 1983-05-20 | 1986-01-27 | Immuno Ag | Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation |
CA1237998A (en) * | 1984-04-14 | 1988-06-14 | Akihiro Ginnaga | Method for purification of filamentous hemagglutinin |
GB8505882D0 (en) * | 1985-03-07 | 1985-04-11 | Central Blood Lab Authority | Purification of blood coagulation factor viii |
DE3519011A1 (de) * | 1985-05-25 | 1986-11-27 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines materials zur affinitaetschromatographie |
US4656254A (en) * | 1985-12-02 | 1987-04-07 | Miles Laboratories, Inc. | Method of preparing alpha-1-proteinase inhibitor and antithrombin III |
AT399095B (de) * | 1986-03-27 | 1995-03-27 | Vukovich Thomas Dr | Verfahren zur auftrennung von proteinen mittels gradientenelution und vorrichtung zur durchführung des verfahrens |
US4749783A (en) * | 1986-07-11 | 1988-06-07 | Miles Laboratories, Inc. | Viral inactivation and purification of active proteins |
CA1341379C (en) | 1988-04-28 | 2002-07-23 | Welfide Corporation | Purified antithrombin-iii and methods of producing the same |
US5110907A (en) * | 1989-08-01 | 1992-05-05 | Alpha Therapeutic Corporation | Factor viii complex purification using heparin affinity chromatography |
US6562781B1 (en) * | 1995-11-30 | 2003-05-13 | Hamilton Civic Hospitals Research Development Inc. | Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates |
US6491965B1 (en) * | 1995-11-30 | 2002-12-10 | Hamilton Civic Hospitals Research Development, Inc. | Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates |
US7045585B2 (en) * | 1995-11-30 | 2006-05-16 | Hamilton Civic Hospital Research Development Inc. | Methods of coating a device using anti-thrombin heparin |
US5989593A (en) * | 1996-11-20 | 1999-11-23 | Yoshitomi Pharmaceutical Industries, Ltd. | Method for producing antithrombin-III, method for purifying it, and preparation containing it |
AT405739B (de) | 1997-09-19 | 1999-11-25 | Immuno Ag | Verfahren zur reinigung von antithrombin iii |
US8563693B2 (en) * | 2001-01-26 | 2013-10-22 | Acceleration Biopharmaceuticals, Inc. | Method of treating human immunodeficiency virus infection in a mammal comprising administering heparin-activated antithrombin III |
WO2002058638A2 (en) * | 2001-01-26 | 2002-08-01 | The General Hospital Corporation | Serpin drugs for treatment of hiv infection and method of use thereof |
SE0203770D0 (sv) * | 2002-12-19 | 2002-12-19 | Biovitrum Ab | Method of separation |
MX2007002085A (es) | 2004-08-20 | 2007-07-19 | Prometic Biosciences Ltd | Esquemas de aislamiento y purificacion consecutivos de proteinas mediante cromatografia de afinidad. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE366760B (fi) * | 1967-12-18 | 1974-05-06 | J Sjoevall | |
DE1907738A1 (de) * | 1969-02-15 | 1970-08-13 | Bayer Ag | Verfahren zur Abtrennung des Trypsin-Plasmin-Inhibitors vom Thrombin-Inhibitor in handelsueblichen Hirudinpraeparaten und in Hirudinrohpraeparaten |
-
1971
- 1971-09-08 SE SE7111350A patent/SE392038B/xx unknown
-
1972
- 1972-07-24 IL IL39982A patent/IL39982A/xx unknown
- 1972-07-26 FI FI722094A patent/FI50583C/fi active
- 1972-08-07 BE BE787284A patent/BE787284A/xx not_active IP Right Cessation
- 1972-08-08 SU SU1818160A patent/SU447876A3/ru active
- 1972-08-23 JP JP8439172A patent/JPS5545528B2/ja not_active Expired
- 1972-08-28 CS CS7906A patent/CS172957B2/cs unknown
- 1972-08-30 ES ES406199A patent/ES406199A1/es not_active Expired
- 1972-08-31 DK DK430972AA patent/DK131128B/da not_active IP Right Cessation
- 1972-09-01 ZA ZA726024A patent/ZA726024B/xx unknown
- 1972-09-01 NL NL727211953A patent/NL154118B/xx not_active IP Right Cessation
- 1972-09-06 DE DE2243688A patent/DE2243688C3/de not_active Expired
- 1972-09-06 IE IE1211/72A patent/IE36670B1/xx unknown
- 1972-09-06 PL PL1972157623A patent/PL83490B1/pl unknown
- 1972-09-06 CA CA151,075A patent/CA979805A/en not_active Expired
- 1972-09-06 US US00286732A patent/US3842061A/en not_active Expired - Lifetime
- 1972-09-06 AU AU46373/72A patent/AU461865B2/en not_active Expired
- 1972-09-07 GB GB4158872A patent/GB1356229A/en not_active Expired
- 1972-09-07 NO NO3184/72A patent/NO135302C/no unknown
- 1972-09-07 AT AT768872A patent/AT324549B/de not_active IP Right Cessation
- 1972-09-08 CH CH1324072A patent/CH577829A5/xx not_active IP Right Cessation
- 1972-09-08 HU HUKA1355A patent/HU165070B/hu unknown
- 1972-09-08 FR FR7231896A patent/FR2154483B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL39982A (en) | 1974-11-29 |
DK131128C (fi) | 1975-11-03 |
JPS5545528B2 (fi) | 1980-11-18 |
NL7211953A (fi) | 1973-03-12 |
SE392038B (sv) | 1977-03-14 |
AU461865B2 (en) | 1975-06-05 |
CS172957B2 (fi) | 1977-01-28 |
FI50583B (fi) | 1976-02-02 |
DE2243688A1 (de) | 1973-03-22 |
NO135302B (fi) | 1976-12-13 |
FR2154483B1 (fi) | 1977-01-14 |
AT324549B (de) | 1975-09-10 |
NL154118B (nl) | 1977-08-15 |
IE36670B1 (en) | 1977-01-19 |
BE787284A (fr) | 1972-12-01 |
FR2154483A1 (fi) | 1973-05-11 |
IL39982A0 (en) | 1972-09-28 |
DK131128B (da) | 1975-06-02 |
DE2243688B2 (de) | 1978-06-15 |
SU447876A3 (ru) | 1974-10-25 |
US3842061A (en) | 1974-10-15 |
AU4637372A (en) | 1974-03-14 |
IE36670L (en) | 1973-03-08 |
NO135302C (fi) | 1977-03-23 |
ZA726024B (en) | 1973-05-30 |
ES406199A1 (es) | 1975-07-01 |
JPS4835017A (fi) | 1973-05-23 |
GB1356229A (en) | 1974-06-12 |
DE2243688C3 (de) | 1984-05-10 |
PL83490B1 (fi) | 1975-12-31 |
CA979805A (en) | 1975-12-16 |
CH577829A5 (fi) | 1976-07-30 |
HU165070B (fi) | 1974-06-28 |
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