IL33150A - 3alpha-hydroxy-17-hydrazono-5beta-androstan-11-one and process for the preparation thereof - Google Patents
3alpha-hydroxy-17-hydrazono-5beta-androstan-11-one and process for the preparation thereofInfo
- Publication number
- IL33150A IL33150A IL33150A IL3315066A IL33150A IL 33150 A IL33150 A IL 33150A IL 33150 A IL33150 A IL 33150A IL 3315066 A IL3315066 A IL 3315066A IL 33150 A IL33150 A IL 33150A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- 5beta
- 3alpha
- androstan
- hydrazono
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 4
- 238000002360 preparation method Methods 0.000 title claims description 4
- XDCANDMRXHHXBQ-UKZLPJRTSA-N (3R,5R,8S,9S,10S,13S,14S)-17-hydrazinylidene-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one Chemical compound O[C@H]1C[C@H]2CC[C@H]3[C@@H]4CCC([C@@]4(C)CC([C@@H]3[C@]2(CC1)C)=O)=NN XDCANDMRXHHXBQ-UKZLPJRTSA-N 0.000 title 1
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical class OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000013019 agitation Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9431A FR1519510A (fr) | 1965-03-16 | 1965-03-16 | 17-halogéno stéroïdes et procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL33150A true IL33150A (en) | 1970-01-29 |
Family
ID=8574079
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL33150A IL33150A (en) | 1965-03-16 | 1966-03-08 | 3alpha-hydroxy-17-hydrazono-5beta-androstan-11-one and process for the preparation thereof |
| IL25330A IL25330A (en) | 1965-03-16 | 1966-03-08 | 17-halo-delta16-steroids of the androstane series |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL25330A IL25330A (en) | 1965-03-16 | 1966-03-08 | 17-halo-delta16-steroids of the androstane series |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3354037A (cs) |
| AT (1) | AT260439B (cs) |
| BE (1) | BE677699A (cs) |
| BR (1) | BR6677886D0 (cs) |
| CH (1) | CH457421A (cs) |
| DE (1) | DE1543435B1 (cs) |
| DK (1) | DK113776B (cs) |
| ES (1) | ES324213A1 (cs) |
| FR (1) | FR1519510A (cs) |
| GB (1) | GB1064599A (cs) |
| IL (2) | IL33150A (cs) |
| NL (1) | NL125672C (cs) |
| SE (1) | SE312802B (cs) |
-
0
- NL NL125672D patent/NL125672C/xx active
-
1965
- 1965-03-16 FR FR9431A patent/FR1519510A/fr not_active Expired
-
1966
- 1966-03-04 DK DK114266AA patent/DK113776B/da unknown
- 1966-03-08 IL IL33150A patent/IL33150A/en unknown
- 1966-03-08 US US532563A patent/US3354037A/en not_active Expired - Lifetime
- 1966-03-08 IL IL25330A patent/IL25330A/xx unknown
- 1966-03-11 BE BE677699D patent/BE677699A/xx unknown
- 1966-03-14 SE SE3380/66A patent/SE312802B/xx unknown
- 1966-03-15 ES ES0324213A patent/ES324213A1/es not_active Expired
- 1966-03-15 CH CH370366A patent/CH457421A/fr unknown
- 1966-03-16 BR BR177886/66A patent/BR6677886D0/pt unknown
- 1966-03-16 DE DE19661543435 patent/DE1543435B1/de active Pending
- 1966-03-16 GB GB11551/66A patent/GB1064599A/en not_active Expired
- 1966-03-16 AT AT250466A patent/AT260439B/de active
Also Published As
| Publication number | Publication date |
|---|---|
| BE677699A (cs) | 1966-09-12 |
| NL125672C (cs) | |
| DK113776B (da) | 1969-04-28 |
| IL25330A (en) | 1969-12-31 |
| CH457421A (fr) | 1968-06-15 |
| GB1064599A (en) | 1967-04-05 |
| SE312802B (cs) | 1969-07-28 |
| AT260439B (de) | 1968-03-11 |
| BR6677886D0 (pt) | 1973-09-11 |
| ES324213A1 (es) | 1967-02-01 |
| US3354037A (en) | 1967-11-21 |
| DE1543435B1 (de) | 1970-04-30 |
| FR1519510A (fr) | 1968-04-05 |
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