IL303115A - Detection of hematological disorders using cell-free DNA in blood - Google Patents
Detection of hematological disorders using cell-free DNA in bloodInfo
- Publication number
- IL303115A IL303115A IL303115A IL30311523A IL303115A IL 303115 A IL303115 A IL 303115A IL 303115 A IL303115 A IL 303115A IL 30311523 A IL30311523 A IL 30311523A IL 303115 A IL303115 A IL 303115A
- Authority
- IL
- Israel
- Prior art keywords
- dna
- methylation
- cell
- plasma
- blood
- Prior art date
Links
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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PCT/CN2017/086509 WO2017206888A1 (en) | 2016-05-30 | 2017-05-30 | Detecting hematological disorders using cell-free dna in blood |
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EP3889272A1 (en) | 2014-07-18 | 2021-10-06 | The Chinese University of Hong Kong | Methylation pattern analysis of tissues in dna mixture |
CA3025708A1 (en) | 2016-05-30 | 2017-12-07 | The Chinese University Of Hong Kong | Detecting hematological disorders using cell-free dna in blood |
AU2017369018B2 (en) | 2016-11-30 | 2021-02-25 | The Chinese University Of Hong Kong | Analysis of cell-free DNA in urine and other samples |
DK3574108T3 (da) | 2017-01-25 | 2024-09-16 | The Chinese Univ Of Hong Kong | Diagnostisk anvendelse ved brug af nukleinsyrefragment |
KR20200035427A (ko) | 2017-07-26 | 2020-04-03 | 더 차이니즈 유니버시티 오브 홍콩 | 세포-무함유 바이러스 핵산을 사용하는 암 스크리닝의 증강 |
WO2019173283A1 (en) | 2018-03-05 | 2019-09-12 | Marquette University | Method and apparatus for non-invasive hemoglobin level prediction |
TW202102687A (zh) | 2019-03-25 | 2021-01-16 | 香港中文大學 | 確定循環核酸之線性及環狀形式 |
CN110361531B (zh) * | 2019-08-02 | 2023-04-11 | 天津医科大学总医院 | 一种检测微粒促凝活性的实验方法 |
CN115175985A (zh) * | 2019-12-20 | 2022-10-11 | 威廉马歇莱思大学 | 从未经处理的生物样本中提取单链dna和rna并测序的方法 |
CN111518876B (zh) * | 2020-05-11 | 2023-01-13 | 润方(北京)生物医药研究院有限公司 | 一种牛血红蛋白制品中牛源基因组dna定量检测方法及其应用 |
KR102517894B1 (ko) * | 2021-02-23 | 2023-04-04 | 연세대학교 산학협력단 | 당뇨발에 의한 하지 절단 수술의 치료 반응성을 예측하는 방법 |
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US20090176655A1 (en) * | 2007-11-16 | 2009-07-09 | Oncomethylome Sciences Sa | Methylation detection |
US20110028333A1 (en) * | 2009-05-01 | 2011-02-03 | Brown University | Diagnosing, prognosing, and early detection of cancers by dna methylation profiling |
NZ601079A (en) | 2010-01-26 | 2014-08-29 | Nipd Genetics Ltd | Methods and compositions for noninvasive prenatal diagnosis of fetal aneuploidies |
WO2011130751A1 (en) | 2010-04-16 | 2011-10-20 | Chronix Biomedical | Breast cancer associated circulating nucleic acid biomarkers |
MX370249B (es) | 2010-11-30 | 2019-12-06 | Univ Hong Kong Chinese | Deteccion de aberraciones genéticas o moleculares asociadas con el cáncer. |
WO2012103031A2 (en) | 2011-01-25 | 2012-08-02 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities |
US20140178348A1 (en) | 2011-05-25 | 2014-06-26 | The Regents Of The University Of California | Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies |
ES2693672T3 (es) | 2011-09-26 | 2018-12-13 | Qiagen Gmbh | Método rápido para aislar ácidos nucleicos extracelulares |
ES2729554T3 (es) | 2011-10-21 | 2019-11-04 | Chronix Biomedical | Biomarcadores de ácidos nucleicos en circulación asociados al cáncer colorrectal |
US9732390B2 (en) * | 2012-09-20 | 2017-08-15 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of fetus or tumor from plasma |
NZ706269A (en) * | 2012-09-20 | 2016-08-26 | Univ Hong Kong Chinese | Non-invasive determination of methylome of fetus or tumor from plasma |
EP3099822A4 (en) | 2014-01-30 | 2017-08-30 | The Regents of the University of California | Methylation haplotyping for non-invasive diagnosis (monod) |
LT4026917T (lt) | 2014-04-14 | 2024-03-12 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. | Ląstelių ar audinio žūties nustatymo arba iš audinio ar ląstelės gautos dnr kilmės nustatymo dnr metilinimo analizės būdu metodas ir rinkinys |
EP3140421B8 (en) | 2014-05-09 | 2020-05-06 | Eurofins LifeCodexx GmbH | Detection of dna that originates from a specific cell-type and related methods |
EP3889272A1 (en) | 2014-07-18 | 2021-10-06 | The Chinese University of Hong Kong | Methylation pattern analysis of tissues in dna mixture |
US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
CA3025708A1 (en) | 2016-05-30 | 2017-12-07 | The Chinese University Of Hong Kong | Detecting hematological disorders using cell-free dna in blood |
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