IL302986A - A non-aqueous gel preparation - Google Patents
A non-aqueous gel preparationInfo
- Publication number
- IL302986A IL302986A IL302986A IL30298623A IL302986A IL 302986 A IL302986 A IL 302986A IL 302986 A IL302986 A IL 302986A IL 30298623 A IL30298623 A IL 30298623A IL 302986 A IL302986 A IL 302986A
- Authority
- IL
- Israel
- Prior art keywords
- benzyl
- bicyclo
- carboxamide
- heptane
- composition
- Prior art date
Links
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- FBCXLUDELSDWOT-UHFFFAOYSA-N 4-chloro-N-[[4-(pentafluoro-lambda6-sulfanyl)phenyl]methyl]benzamide Chemical compound ClC1=CC=C(C(=O)NCC2=CC=C(C=C2)S(F)(F)(F)(F)F)C=C1 FBCXLUDELSDWOT-UHFFFAOYSA-N 0.000 claims description 5
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- NTYZDAJPNNBYED-UHFFFAOYSA-M sodium;2-(2-dodecanoyloxypropanoyloxy)propanoate Chemical compound [Na+].CCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O NTYZDAJPNNBYED-UHFFFAOYSA-M 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20208665 | 2020-11-19 | ||
| PCT/EP2021/082108 WO2022106523A1 (fr) | 2020-11-19 | 2021-11-18 | Composition de gel non aqueux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL302986A true IL302986A (en) | 2023-07-01 |
Family
ID=73497626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL302986A IL302986A (en) | 2020-11-19 | 2021-11-18 | A non-aqueous gel preparation |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240009149A1 (fr) |
| EP (1) | EP4247332A1 (fr) |
| JP (1) | JP2023550422A (fr) |
| KR (1) | KR20230107307A (fr) |
| CN (1) | CN116600787A (fr) |
| AU (1) | AU2021380914B2 (fr) |
| CA (1) | CA3198930A1 (fr) |
| CL (1) | CL2023001413A1 (fr) |
| IL (1) | IL302986A (fr) |
| MX (1) | MX2023005822A (fr) |
| WO (1) | WO2022106523A1 (fr) |
| ZA (1) | ZA202305093B (fr) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR960010618Y1 (ko) | 1991-09-06 | 1996-12-20 | 홍종훈 | 좌변기용 세척수 공급장치 |
| EP2192838A4 (fr) * | 2007-08-15 | 2011-07-27 | Harvard College | Inhibiteurs hétérocycliques de la nécroptose |
| WO2010011466A2 (fr) * | 2008-06-27 | 2010-01-28 | Otonomy, Inc. | Compositions de modulation du snc à libération contrôlée et procédés de traitement des troubles otiques |
| US8399018B2 (en) | 2008-07-21 | 2013-03-19 | Otonomy, Inc. | Controlled release ion channel modulator compositions and methods for the treatment of otic disorders |
| EP2675409A4 (fr) | 2011-02-18 | 2015-04-08 | Otonomy Inc | Prévention de l'ototoxicité induite par un médicament et rétablissement après ototoxicité induite par un médicament |
| KR20230041081A (ko) * | 2011-05-15 | 2023-03-23 | 에이세러스 바이오파마 인크. | 비내용 테스토스테론 바이오-접착제 겔 제형 및 남성의 성선기능저하증을 치료하기 위한 그의 용도 |
| US10130514B2 (en) | 2011-09-26 | 2018-11-20 | Incube Labs, Llc | System and method for delivery of a therapeutic agent to the inner ear |
| WO2014076569A2 (fr) | 2012-11-14 | 2014-05-22 | Trimel Biopharma Srl | Formulations de testostérone topiques à libération commandée et procédés associés |
| JP6700291B2 (ja) * | 2015-02-15 | 2020-05-27 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | １−（ｈｅｔ）アリールスルホニル−（ピロリジン又はピペリジン）−２−カルボキサミド誘導体、及びｔｒｐａ１拮抗薬としてのそれらの使用 |
| JP7033789B2 (ja) | 2016-06-29 | 2022-03-11 | オトノミー，インク． | トリグリセリド耳用製剤とその使用 |
| CA3050361A1 (fr) * | 2017-01-20 | 2018-07-26 | M et P Pharma AG | Compositions pharmaceutiques nasales pour reduire les risques d'exposition a des polluants atmospheriques |
| WO2018140792A2 (fr) * | 2017-01-27 | 2018-08-02 | Otonomy, Inc. | Mutants de neurotrophine pour le traitement de la perte d'audition et d'autres troubles otiques |
| EP3366683A1 (fr) * | 2017-02-28 | 2018-08-29 | Acousia Therapeutics GmbH | Amides, acetamides et ureas cycliques pour ouvris les voies de calcium |
| WO2019126783A1 (fr) * | 2017-12-22 | 2019-06-27 | Otonomy, Inc. | Formulations otiques à base de triglycérides et leurs utilisations |
| KR20200108873A (ko) * | 2018-01-09 | 2020-09-21 | 오토노미, 인코포레이티드 | 성장 인자 귀 제제 |
| CA3097090A1 (fr) * | 2018-04-17 | 2019-10-24 | M et P Pharma AG | Compositions et methodes d'administration intranasale de pregnenolone |
| US20210186943A1 (en) | 2018-04-25 | 2021-06-24 | Otonomy, Inc. | Otic formulations for drug-induced ototoxicity |
| TW202408984A (zh) * | 2018-11-26 | 2024-03-01 | 美商富曼西公司 | 用於防治無脊椎害蟲的間二醯胺化合物 |
-
2021
- 2021-11-18 CA CA3198930A patent/CA3198930A1/fr active Pending
- 2021-11-18 EP EP21811355.3A patent/EP4247332A1/fr active Pending
- 2021-11-18 US US18/252,432 patent/US20240009149A1/en active Pending
- 2021-11-18 MX MX2023005822A patent/MX2023005822A/es unknown
- 2021-11-18 IL IL302986A patent/IL302986A/en unknown
- 2021-11-18 CN CN202180078209.8A patent/CN116600787A/zh active Pending
- 2021-11-18 JP JP2023530168A patent/JP2023550422A/ja active Pending
- 2021-11-18 KR KR1020237019621A patent/KR20230107307A/ko unknown
- 2021-11-18 AU AU2021380914A patent/AU2021380914B2/en active Active
- 2021-11-18 WO PCT/EP2021/082108 patent/WO2022106523A1/fr active Application Filing
-
2023
- 2023-05-08 ZA ZA2023/05093A patent/ZA202305093B/en unknown
- 2023-05-17 CL CL2023001413A patent/CL2023001413A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2023001413A1 (es) | 2023-10-30 |
| JP2023550422A (ja) | 2023-12-01 |
| ZA202305093B (en) | 2023-11-29 |
| US20240009149A1 (en) | 2024-01-11 |
| AU2021380914A1 (en) | 2023-06-22 |
| CN116600787A (zh) | 2023-08-15 |
| WO2022106523A1 (fr) | 2022-05-27 |
| MX2023005822A (es) | 2023-05-31 |
| EP4247332A1 (fr) | 2023-09-27 |
| KR20230107307A (ko) | 2023-07-14 |
| AU2021380914B2 (en) | 2024-08-15 |
| CA3198930A1 (fr) | 2022-05-27 |
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