IL295626A - A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor - Google Patents
A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitorInfo
- Publication number
- IL295626A IL295626A IL295626A IL29562622A IL295626A IL 295626 A IL295626 A IL 295626A IL 295626 A IL295626 A IL 295626A IL 29562622 A IL29562622 A IL 29562622A IL 295626 A IL295626 A IL 295626A
- Authority
- IL
- Israel
- Prior art keywords
- braf
- dabrafenib
- compound
- seq
- pharmaceutic
- Prior art date
Links
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US202062983020P | 2020-02-28 | 2020-02-28 | |
| PCT/IB2021/051641 WO2021171260A2 (en) | 2020-02-28 | 2021-02-26 | A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor or a pd-1 inhibitor |
Publications (1)
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| IL295626A true IL295626A (en) | 2022-10-01 |
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| IL295626A IL295626A (en) | 2020-02-28 | 2021-02-26 | A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor |
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| EP (1) | EP4110341A2 (de) |
| JP (1) | JP2023516155A (de) |
| KR (1) | KR20220148846A (de) |
| CN (1) | CN115279374A (de) |
| AU (1) | AU2021225491A1 (de) |
| CA (1) | CA3173356A1 (de) |
| IL (1) | IL295626A (de) |
| TW (1) | TW202146024A (de) |
| WO (1) | WO2021171260A2 (de) |
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| IL129299A0 (en) | 1999-03-31 | 2000-02-17 | Mor Research Applic Ltd | Monoclonal antibodies antigens and diagnosis of malignant diseases |
| IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
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| JP2013512251A (ja) | 2009-11-24 | 2013-04-11 | アンプリミューン、インコーポレーテッド | Ｐｄ−ｌ１／ｐｄ−ｌ２の同時阻害 |
| EP2545078A1 (de) | 2010-03-11 | 2013-01-16 | UCB Pharma, S.A. | Pd-1-antikörper |
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| AU2017329090B9 (en) * | 2016-09-19 | 2019-09-05 | Novartis Ag | Therapeutic combinations comprising a RAF inhibitor and a ERK inhibitor |
| JP2021519285A (ja) * | 2018-03-30 | 2021-08-10 | ノバルティス アーゲー | ダブラフェニブ、トラメチニブ及びｅｒｋ阻害剤を含む医薬品の三重の組合せ |
-
2021
- 2021-02-26 AU AU2021225491A patent/AU2021225491A1/en not_active Abandoned
- 2021-02-26 WO PCT/IB2021/051641 patent/WO2021171260A2/en not_active Ceased
- 2021-02-26 TW TW110107183A patent/TW202146024A/zh unknown
- 2021-02-26 EP EP21739775.1A patent/EP4110341A2/de not_active Withdrawn
- 2021-02-26 IL IL295626A patent/IL295626A/en unknown
- 2021-02-26 CA CA3173356A patent/CA3173356A1/en active Pending
- 2021-02-26 JP JP2022551299A patent/JP2023516155A/ja active Pending
- 2021-02-26 CN CN202180017128.7A patent/CN115279374A/zh active Pending
- 2021-02-26 KR KR1020227032733A patent/KR20220148846A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021171260A3 (en) | 2021-10-07 |
| TW202146024A (zh) | 2021-12-16 |
| JP2023516155A (ja) | 2023-04-18 |
| WO2021171260A2 (en) | 2021-09-02 |
| AU2021225491A1 (en) | 2022-10-20 |
| CA3173356A1 (en) | 2021-09-02 |
| KR20220148846A (ko) | 2022-11-07 |
| EP4110341A2 (de) | 2023-01-04 |
| CN115279374A (zh) | 2022-11-01 |
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