IL29485A - Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines - Google Patents

Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Info

Publication number
IL29485A
IL29485A IL29485A IL2948568A IL29485A IL 29485 A IL29485 A IL 29485A IL 29485 A IL29485 A IL 29485A IL 2948568 A IL2948568 A IL 2948568A IL 29485 A IL29485 A IL 29485A
Authority
IL
Israel
Prior art keywords
benzazepines
tetrahydro
preparation
Prior art date
Application number
IL29485A
Other languages
English (en)
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Publication of IL29485A publication Critical patent/IL29485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Drawers Of Furniture (AREA)
IL29485A 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines IL29485A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
IL29485A true IL29485A (en) 1971-07-28

Family

ID=25690322

Family Applications (1)

Application Number Title Priority Date Filing Date
IL29485A IL29485A (en) 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Country Status (13)

Country Link
US (1) US3652543A (instruction)
AT (1) AT275533B (instruction)
BE (1) BE710872A (instruction)
CH (2) CH481110A (instruction)
DE (2) DE1695124A1 (instruction)
DK (1) DK115473B (instruction)
ES (1) ES350574A1 (instruction)
FR (2) FR1560654A (instruction)
GB (2) GB1221324A (instruction)
IL (1) IL29485A (instruction)
NL (1) NL6802257A (instruction)
NO (1) NO124369B (instruction)
SE (1) SE342043B (instruction)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze
DE2016136A1 (de) * 1970-04-04 1971-10-14 C H Boehnnger Sohn, 6507 Ingel heim Neue 7 Acyl 1,2,4,5 tetrahydro (3H) 3 benzazepine
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
DE2207430C3 (de) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
DE3272044D1 (de) * 1981-11-27 1986-08-21 Smithkline Beckman Corp 3-benzazepines as alpha-2 antagonists
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP0254737B1 (en) * 1986-01-16 1990-07-25 Schering Corporation Fused benzazepines
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ATE78467T1 (de) * 1987-07-15 1992-08-15 Schering Corp Kondensierte benzazepine.
ES2075429T3 (es) * 1990-02-02 1995-10-01 Schering Corp Derivados de 4,5-cicloalcano-3-benzazepin-7-ol y sus usos.
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
US20030220661A1 (en) * 2002-05-21 2003-11-27 Heartstent Corporation Transmyocardial implant delivery system
DK2332921T3 (en) 2003-06-17 2016-05-09 Arena Pharm Inc 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3benzazepine hydrochloride
CA2529320C (en) * 2003-06-17 2013-03-05 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
RS50996B (sr) 2004-12-21 2010-10-31 Arena Pharmaceuticals Inc. Kristalni oblici (r)-8-hloro-1-metil-2,3,4,5-tetrahidro-1h-benzazepin hlorhidrat
WO2006071740A2 (en) 2004-12-23 2006-07-06 Arena Pharmaceuticals, Inc. 5ht2c receptor modulator compositions and methods of use
SG10201508066VA (en) 2006-04-03 2015-10-29 Arena Pharm Inc Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
WO2008070111A2 (en) * 2006-12-05 2008-06-12 Arena Pharmaceuticals, Inc. Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
CN102015591B (zh) * 2008-03-04 2014-01-29 艾尼纳制药公司 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
WO2012030927A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
US8999970B2 (en) 2010-09-01 2015-04-07 Arena Pharmaceuticals, Inc. Administration of an anti-obesity compound to individuals with renal impairment
US9248133B2 (en) 2010-09-01 2016-02-02 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
WO2014058441A1 (en) 2012-10-09 2014-04-17 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
CH488705A (de) 1970-04-15
DE1668915A1 (de) 1972-03-09
DK115473B (da) 1969-10-13
FR1561479A (instruction) 1969-03-28
ES350574A1 (es) 1969-11-16
SE342043B (instruction) 1972-01-24
GB1221324A (en) 1971-02-03
NO124369B (instruction) 1972-04-10
BE710872A (instruction) 1968-08-16
FR1560654A (instruction) 1969-03-21
NL6802257A (instruction) 1968-08-19
DE1695124A1 (de) 1970-08-20
US3652543A (en) 1972-03-28
AT275533B (de) 1969-10-27
GB1222397A (en) 1971-02-10
CH481110A (de) 1969-11-15

Similar Documents

Publication Publication Date Title
IL29485A (en) Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines
YU39440B (en) Process for the manufacture of new 3-methylthio-4-amino-1,2,4-triazine-5-ones
IL29735A0 (en) Process for the preparation of pyrazinoylguanidines
IL29958A0 (en) Method for preparation of levo-1-n-butyl-2',6'-pipecoloxylidide
IL29214A (en) Process for the preparation of dichloroquinolines
IL30637A0 (en) Process for the preparation of n-tritylimidazoles
YU33723B (en) Process for preparing 2,4-bis-alkylamino-6-chloro-s-triazines
IL37183A (en) Process for the preparation of 2,5-dichloro-4-alkylmercapto-phenols
YU34301B (en) Process for preparing 17 delta-hydroxy-(acyloxy-11beta-methyl-19-norpregn-4-ene-3,20-dions
IL29620A (en) Process for the preparation of 1-n-butyl-2',6'-pipecoloxylidide
IL30710A0 (en) Process for the preparation of pyrazinaminoguanidines
CA769764A (en) Process for the preparation of 1,5,9-cyclododecatrienes
CA752411A (en) Process for the preparation of iminobibenzyl
CA765757A (en) Process for the preparation of n2f4
IL29910A (en) New process for preparing a-nor-estra-3,9,11-triene-2-ones
CA751434A (en) Process for the preparation of substituted 1,3,4-thiodiazoles
IL23552A (en) Process for the preparation of steroid-delta4,9,11-trienes
AU428013B2 (en) PROCESS FOR THE PREPARATION OF 1-n-BUTYL-2', 6'-PIPECOLOXYLIDIDE
MY7000055A (en) A process for the manufacture of benidiaz (1,4) epines
AU417501B2 (en) PROCESS FOR THE MANUFACTURE OF 15, 16b-METHYLENE-STEROIDS
IL31055A0 (en) Process for the preparation of bis-chromones
HRP940111B1 (en) Process for the preparation of aminoacetilaminobenzophenone
CA750908A (en) PROCESS FOR THE PREPARATION OF 17.alpha.-ETHYNYL-19-NORANDROSTENE COMPOUNDS
IL30404A (en) 1,3-benzoxazine-2-thiones and process for the preparation thereof
CA771215A (en) Process for the manufacture of 2-chlorobutadiene-(1,3)