IL294035A - A multispecific antibody with binding specificity for human il-13 and il-17 - Google Patents

A multispecific antibody with binding specificity for human il-13 and il-17

Info

Publication number
IL294035A
IL294035A IL294035A IL29403522A IL294035A IL 294035 A IL294035 A IL 294035A IL 294035 A IL294035 A IL 294035A IL 29403522 A IL29403522 A IL 29403522A IL 294035 A IL294035 A IL 294035A
Authority
IL
Israel
Prior art keywords
seq
sequence given
cdr
specific antibody
human
Prior art date
Application number
IL294035A
Other languages
English (en)
Hebrew (he)
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of IL294035A publication Critical patent/IL294035A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL294035A 2019-12-20 2020-12-18 A multispecific antibody with binding specificity for human il-13 and il-17 IL294035A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1919061.0A GB201919061D0 (en) 2019-12-20 2019-12-20 Multi-specific antibody
PCT/EP2020/087046 WO2021123186A1 (en) 2019-12-20 2020-12-18 Multi-specific antibody with binding specificity for human il-13 and il-17

Publications (1)

Publication Number Publication Date
IL294035A true IL294035A (en) 2022-08-01

Family

ID=69323008

Family Applications (1)

Application Number Title Priority Date Filing Date
IL294035A IL294035A (en) 2019-12-20 2020-12-18 A multispecific antibody with binding specificity for human il-13 and il-17

Country Status (20)

Country Link
US (1) US12570738B2 (https=)
EP (1) EP4077381A1 (https=)
JP (1) JP7689125B2 (https=)
KR (1) KR20220117307A (https=)
CN (1) CN114846026A (https=)
AR (1) AR120818A1 (https=)
AU (1) AU2020407279A1 (https=)
BR (1) BR112022011627A2 (https=)
CA (1) CA3164276A1 (https=)
CL (2) CL2022001685A1 (https=)
CO (1) CO2022009711A2 (https=)
EC (1) ECSP22054471A (https=)
GB (1) GB201919061D0 (https=)
IL (1) IL294035A (https=)
MX (1) MX2022007150A (https=)
PE (1) PE20221173A1 (https=)
PH (1) PH12022551411A1 (https=)
TW (1) TW202130365A (https=)
WO (1) WO2021123186A1 (https=)
ZA (1) ZA202207715B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6871948B2 (ja) 2016-04-27 2021-05-19 アッヴィ・インコーポレイテッド 抗ｉｌ−１３抗体を使用する、ｉｌ−１３活性が有害である疾患の治療方法
WO2025238133A1 (en) 2024-05-17 2025-11-20 UCB Biopharma SRL Multispecific antibody with binding specificity for il-11 and il-17

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Also Published As

Publication number Publication date
PH12022551411A1 (en) 2023-11-20
JP2023507280A (ja) 2023-02-22
TW202130365A (zh) 2021-08-16
US20230087378A1 (en) 2023-03-23
CN114846026A (zh) 2022-08-02
BR112022011627A2 (pt) 2022-09-13
ECSP22054471A (es) 2022-08-31
MX2022007150A (es) 2022-07-19
CA3164276A1 (en) 2021-06-24
CO2022009711A2 (es) 2022-07-19
PE20221173A1 (es) 2022-07-25
ZA202207715B (en) 2024-01-31
AU2020407279A1 (en) 2022-08-11
CL2022001685A1 (es) 2023-05-26
WO2021123186A1 (en) 2021-06-24
AR120818A1 (es) 2022-03-23
EP4077381A1 (en) 2022-10-26
GB201919061D0 (en) 2020-02-05
KR20220117307A (ko) 2022-08-23
CL2023002975A1 (es) 2024-04-01
JP7689125B2 (ja) 2025-06-05
US12570738B2 (en) 2026-03-10

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