IL293326A - Polymorphic Carbazole History and Uses - Google Patents

Polymorphic Carbazole History and Uses

Info

Publication number
IL293326A
IL293326A IL293326A IL29332622A IL293326A IL 293326 A IL293326 A IL 293326A IL 293326 A IL293326 A IL 293326A IL 29332622 A IL29332622 A IL 29332622A IL 293326 A IL293326 A IL 293326A
Authority
IL
Israel
Prior art keywords
compound
cancer
present
salt
pct
Prior art date
Application number
IL293326A
Other languages
English (en)
Hebrew (he)
Original Assignee
Ikena Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ikena Oncology Inc filed Critical Ikena Oncology Inc
Publication of IL293326A publication Critical patent/IL293326A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL293326A 2019-11-26 2020-11-25 Polymorphic Carbazole History and Uses IL293326A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962940481P 2019-11-26 2019-11-26
PCT/US2020/062197 WO2021108528A1 (en) 2019-11-26 2020-11-25 Polymorphic carbazole derivatives and uses thereof

Publications (1)

Publication Number Publication Date
IL293326A true IL293326A (en) 2022-07-01

Family

ID=73856339

Family Applications (1)

Application Number Title Priority Date Filing Date
IL293326A IL293326A (en) 2019-11-26 2020-11-25 Polymorphic Carbazole History and Uses

Country Status (13)

Country Link
US (3) US11591339B2 (enExample)
EP (2) EP4529955A3 (enExample)
JP (2) JP2023502531A (enExample)
CN (2) CN122404338A (enExample)
AU (1) AU2020394424A1 (enExample)
CA (1) CA3159317A1 (enExample)
ES (1) ES3028099T3 (enExample)
FI (1) FI4065582T3 (enExample)
IL (1) IL293326A (enExample)
MX (2) MX2022006308A (enExample)
PL (1) PL4065582T3 (enExample)
PT (1) PT4065582T (enExample)
WO (1) WO2021108528A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019012431A (es) 2017-04-21 2020-08-03 Ikena Oncology Inc Inhibidores del receptor de hidrocarburos de arilo (ahr) de indol y usos de los mismos.
AU2020394424A1 (en) 2019-11-26 2022-06-16 Ikena Oncology, Inc. Polymorphic carbazole derivatives and uses thereof
WO2021236717A1 (en) 2020-05-20 2021-11-25 Senda Biosciences, Inc. Fused imidazole derivatives as ahr antagonists

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Also Published As

Publication number Publication date
US20210253579A1 (en) 2021-08-19
US20230286990A1 (en) 2023-09-14
JP2023502531A (ja) 2023-01-24
EP4529955A2 (en) 2025-04-02
PL4065582T3 (pl) 2025-08-18
PT4065582T (pt) 2025-05-22
ES3028099T3 (en) 2025-06-18
AU2020394424A1 (en) 2022-06-16
US12162884B2 (en) 2024-12-10
EP4065582B1 (en) 2025-02-19
EP4065582A1 (en) 2022-10-05
CA3159317A1 (en) 2021-06-03
MX2026004523A (es) 2026-05-04
WO2021108528A1 (en) 2021-06-03
US11591339B2 (en) 2023-02-28
MX2022006308A (es) 2022-06-22
JP2025113368A (ja) 2025-08-01
CN115279764B (zh) 2026-04-07
CN122404338A (zh) 2026-07-17
KR20220125231A (ko) 2022-09-14
US20250276975A1 (en) 2025-09-04
CN115279764A (zh) 2022-11-01
EP4529955A3 (en) 2025-07-16
FI4065582T3 (fi) 2025-05-25

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