IL284565A - A system for administering avalopertide transdermally and a method of use - Google Patents
A system for administering avalopertide transdermally and a method of useInfo
- Publication number
- IL284565A IL284565A IL284565A IL28456521A IL284565A IL 284565 A IL284565 A IL 284565A IL 284565 A IL284565 A IL 284565A IL 28456521 A IL28456521 A IL 28456521A IL 284565 A IL284565 A IL 284565A
- Authority
- IL
- Israel
- Prior art keywords
- abaloparatide
- delivery
- transdermal system
- transdermal
- Prior art date
Links
- BVISQZFBLRSESR-XSCWXTNMSA-N abaloparatide Chemical compound C([C@@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C1=CN=CN1 BVISQZFBLRSESR-XSCWXTNMSA-N 0.000 title 1
- 229950001959 abaloparatide Drugs 0.000 title 1
- 108010038051 abaloparatide Proteins 0.000 title 1
- 229940100640 transdermal system Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962812140P | 2019-02-28 | 2019-02-28 | |
| PCT/IB2020/051699 WO2020174443A1 (en) | 2019-02-28 | 2020-02-27 | Transdermal system for the delivery of abaloparatide and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL284565A true IL284565A (en) | 2021-08-31 |
Family
ID=69811437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL284565A IL284565A (en) | 2019-02-28 | 2021-07-01 | A system for administering avalopertide transdermally and a method of use |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210379162A1 (enExample) |
| EP (1) | EP3930743A1 (enExample) |
| JP (1) | JP2022521563A (enExample) |
| KR (1) | KR20210134324A (enExample) |
| CN (1) | CN113453704A (enExample) |
| AU (1) | AU2020228339A1 (enExample) |
| BR (1) | BR112021012283A2 (enExample) |
| CA (1) | CA3122239A1 (enExample) |
| CO (1) | CO2021007862A2 (enExample) |
| IL (1) | IL284565A (enExample) |
| MX (1) | MX2021007062A (enExample) |
| SG (1) | SG11202106205YA (enExample) |
| TW (1) | TW202037378A (enExample) |
| WO (1) | WO2020174443A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021149012A1 (en) | 2020-01-24 | 2021-07-29 | Radius Health, Inc. | Methods of stimulating bone growth with abalopartide and denosumab |
| CN117586377A (zh) * | 2022-08-10 | 2024-02-23 | 成都奥达生物科技有限公司 | 一种长效阿巴洛肽化合物 |
| CN119113134B (zh) * | 2024-09-13 | 2025-05-16 | 南京羚诺生物医药技术研究院有限公司 | 一种提升阿巴帕肽半衰期的制备方法及其在治疗骨质疏松症中的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20031302A3 (cs) * | 2000-10-13 | 2003-10-15 | Alza Corporation | Prvek zadržující mikrovýčnělkový prvek pro nárazový aplikátor |
| CN101151048A (zh) * | 2004-05-10 | 2008-03-26 | 纳斯泰克制药公司 | 增强甲状旁腺激素粘膜递送的组合物和方法 |
| CA2680690A1 (en) * | 2006-03-15 | 2007-09-20 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
| US8563513B2 (en) * | 2009-03-27 | 2013-10-22 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
| JP6214548B2 (ja) * | 2011-11-29 | 2017-10-18 | ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー | 骨再生のための治療補助薬としてのインスリン−疑似剤 |
| WO2017026462A1 (ja) | 2015-08-07 | 2017-02-16 | 京都府公立大学法人 | 褐色脂肪細胞の調製方法 |
| JP7116680B2 (ja) | 2015-10-09 | 2022-08-10 | キンデーバ ドラッグ デリバリー リミティド パートナーシップ | コーティングされたマイクロニードルアレイのための亜鉛組成物 |
| HUE055658T2 (hu) | 2015-10-09 | 2021-12-28 | Radius Health Inc | PTHRP analógokat tartalmazó készítmények, ezeket tartalmazó transzdermális tapaszok és ezek alkalmazása |
| EP3481414B1 (en) * | 2016-04-18 | 2021-11-03 | Radius Health, Inc. | Formulations of abaloparatide, transdermal patches thereof, and uses thereof |
-
2020
- 2020-02-27 BR BR112021012283-4A patent/BR112021012283A2/pt unknown
- 2020-02-27 MX MX2021007062A patent/MX2021007062A/es unknown
- 2020-02-27 EP EP20711326.7A patent/EP3930743A1/en not_active Withdrawn
- 2020-02-27 SG SG11202106205YA patent/SG11202106205YA/en unknown
- 2020-02-27 CA CA3122239A patent/CA3122239A1/en active Pending
- 2020-02-27 AU AU2020228339A patent/AU2020228339A1/en not_active Abandoned
- 2020-02-27 CN CN202080007632.4A patent/CN113453704A/zh active Pending
- 2020-02-27 TW TW109106617A patent/TW202037378A/zh unknown
- 2020-02-27 JP JP2021532151A patent/JP2022521563A/ja active Pending
- 2020-02-27 WO PCT/IB2020/051699 patent/WO2020174443A1/en not_active Ceased
- 2020-02-27 KR KR1020217027861A patent/KR20210134324A/ko active Pending
-
2021
- 2021-06-15 CO CONC2021/0007862A patent/CO2021007862A2/es unknown
- 2021-07-01 IL IL284565A patent/IL284565A/en unknown
- 2021-08-06 US US17/395,516 patent/US20210379162A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN113453704A (zh) | 2021-09-28 |
| CA3122239A1 (en) | 2020-09-03 |
| US20210379162A1 (en) | 2021-12-09 |
| CO2021007862A2 (es) | 2021-11-19 |
| MX2021007062A (es) | 2021-09-10 |
| WO2020174443A1 (en) | 2020-09-03 |
| BR112021012283A2 (pt) | 2021-09-08 |
| TW202037378A (zh) | 2020-10-16 |
| SG11202106205YA (en) | 2021-07-29 |
| KR20210134324A (ko) | 2021-11-09 |
| EP3930743A1 (en) | 2022-01-05 |
| AU2020228339A1 (en) | 2021-07-01 |
| JP2022521563A (ja) | 2022-04-11 |
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