IL283409A - tyk2 inhibitors and uses thereof - Google Patents
tyk2 inhibitors and uses thereofInfo
- Publication number
- IL283409A IL283409A IL283409A IL28340921A IL283409A IL 283409 A IL283409 A IL 283409A IL 283409 A IL283409 A IL 283409A IL 28340921 A IL28340921 A IL 28340921A IL 283409 A IL283409 A IL 283409A
- Authority
- IL
- Israel
- Prior art keywords
- tyk2 inhibitors
- tyk2
- inhibitors
- Prior art date
Links
- 229940123371 Tyrosine kinase 2 inhibitor Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862773620P | 2018-11-30 | 2018-11-30 | |
| PCT/US2019/063510 WO2020112937A1 (en) | 2018-11-30 | 2019-11-27 | Tyk2 inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL283409A true IL283409A (en) | 2021-07-29 |
Family
ID=70848642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL283409A IL283409A (en) | 2018-11-30 | 2021-05-24 | tyk2 inhibitors and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11053241B2 (enExample) |
| EP (1) | EP3886843A4 (enExample) |
| JP (2) | JP7530360B2 (enExample) |
| CN (1) | CN113271938A (enExample) |
| AU (1) | AU2019389025B2 (enExample) |
| CA (1) | CA3120866A1 (enExample) |
| IL (1) | IL283409A (enExample) |
| WO (1) | WO2020112937A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4327809A3 (en) | 2015-09-02 | 2024-04-17 | Takeda Pharmaceutical Company Limited | Tyk2 inhibitors and uses thereof |
| AU2017345736B2 (en) | 2016-10-21 | 2022-04-07 | Takeda Pharmaceutical Company Limited | TYK2 inhibitors and uses thereof |
| CN113271940A (zh) | 2018-10-15 | 2021-08-17 | 林伯士拉克许米公司 | Tyk2抑制剂和其用途 |
| CA3120866A1 (en) | 2018-11-30 | 2020-06-04 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| JP2024501507A (ja) * | 2020-12-25 | 2024-01-12 | スーチュアン ハイスーク ファーマシューティカル カンパニー リミテッド | ケトヘキソキナーゼ阻害剤及びその用途 |
| WO2022193499A1 (en) | 2021-03-16 | 2022-09-22 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Amino heteroaryl compounds and compositions |
| AU2022378463A1 (en) | 2021-10-25 | 2024-05-09 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
| TW202425965A (zh) * | 2022-09-30 | 2024-07-01 | 日商科研製藥股份有限公司 | 縮環化合物及含有其之醫藥 |
| CN115974751A (zh) * | 2022-12-13 | 2023-04-18 | 山东能源集团新材料有限公司 | 一种吡拉西坦制备方法及系统 |
| IL321581A (en) * | 2022-12-22 | 2025-08-01 | Protekt Therapeutics Ltd | Pyrrolopyridine and pyrrolopyridazine based compounds and use thereof as pkr inhibitors |
| WO2025010294A2 (en) * | 2023-07-03 | 2025-01-09 | Blossomhill Therapeutics, Inc. | Macrocyclic compounds and use as tyk2 inhibitors |
| US11858935B1 (en) | 2023-09-06 | 2024-01-02 | King Faisal University | Pyrrolo[2,3-c][1,7]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors |
| US11891394B1 (en) | 2023-09-06 | 2024-02-06 | King Faisal University | Pyrrolo[2,3-c][1,6]naphthyridine-8-carboxylic acid compounds as CK2 inhibitors |
| US11878978B1 (en) | 2023-09-06 | 2024-01-23 | King Faisal University | Pyrrolo[2,3-c]quinoline compounds as CK2 inhibitors |
| CN117342955A (zh) * | 2023-10-08 | 2024-01-05 | 盐城师范学院 | 一种制备4’-甲基-联苯-2-胺的方法 |
| WO2025222103A1 (en) * | 2024-04-19 | 2025-10-23 | Raythera, Inc. | Stat6 modulators and methods of uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5650270A (en) | 1982-02-01 | 1997-07-22 | Northeastern University | Molecular analytical release tags and their use in chemical analysis |
| US5516931A (en) | 1982-02-01 | 1996-05-14 | Northeastern University | Release tag compounds producing ketone signal groups |
| US4709016A (en) | 1982-02-01 | 1987-11-24 | Northeastern University | Molecular analytical release tags and their use in chemical analysis |
| US4650750A (en) | 1982-02-01 | 1987-03-17 | Giese Roger W | Method of chemical analysis employing molecular release tag compounds |
| PL338575A1 (en) | 1997-08-05 | 2000-11-06 | Pfizer Prod Inc | 4-aminopyrrole(3,2-d)pyrimidines as antagonists of neuropeptide y receptor |
| CN1195755C (zh) | 1999-12-10 | 2005-04-06 | 辉瑞产品公司 | 吡咯并[2,3－d]嘧啶化合物 |
| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
| DE60217322T2 (de) | 2001-04-27 | 2007-10-04 | Zenyaku Kogyo K.K. | Heterocyclische verbindung und antitumormittel, das diese als wirkstoff enthält |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| DE60325740D1 (de) | 2002-08-14 | 2009-02-26 | Silence Therapeutics Ag | Verwendung von protein-kinase-n-beta |
| JP2006523237A (ja) | 2003-04-03 | 2006-10-12 | セマフォア ファーマシューティカルズ， インコーポレイテッド | Ｐｉ−３キナーゼインヒビタープロドラッグ |
| SI1644363T1 (sl) | 2003-05-30 | 2012-07-31 | Gemin X Pharmaceuticals Canada Inc | Triheterociklične spojine sestavki in postopki za zdravljenje raka |
| EP2371835A1 (en) | 2003-07-03 | 2011-10-05 | The Trustees Of The University Of Pennsylvania | Inhibition of syk kinase expression |
| ES2873875T3 (es) | 2004-05-13 | 2021-11-04 | Icos Corp | Quinazolinonas como inhibidores de fosfatidilinositol 3-quinasa delta humano |
| ATE412651T1 (de) * | 2004-06-09 | 2008-11-15 | Glaxo Group Ltd | Pyrrolopyridinderivate |
| EP1787991B2 (en) | 2004-07-28 | 2020-06-24 | Takeda Pharmaceutical Company Limited | PYRROLO[2,3-c]PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE |
| NZ555947A (en) | 2005-01-19 | 2010-11-26 | Rigel Pharmaceuticals Inc | Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
| EP1888550B1 (en) | 2005-05-12 | 2014-06-25 | AbbVie Bahamas Ltd. | Apoptosis promoters |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| US7402325B2 (en) | 2005-07-28 | 2008-07-22 | Phoenix Biotechnology, Inc. | Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander |
| CN101282948A (zh) | 2005-10-07 | 2008-10-08 | 埃克塞里艾克西斯公司 | N-(3-氨基-喹喔啉-2-基)-磺酰胺衍生物及其作为磷脂酰肌醇3-激酶抑制剂的用途 |
| MY167260A (en) | 2005-11-01 | 2018-08-14 | Targegen Inc | Bi-aryl meta-pyrimidine inhibitors of kinases |
| PT1966202E (pt) | 2005-12-13 | 2012-01-03 | Incyte Corp | Pirrolo[2,3-b] pirimidinas e pirrolo[2,3-b]piridinas substituídas com heteroarilo como inibidores de janus quinase |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| BRPI0710874A2 (pt) | 2006-04-26 | 2012-02-14 | Hoffmann La Roche | compostos de tienopirimidina, processos de produção dos referidos compostos, composições farmacêuticas contendo os mesmos, kit, produto, e usos dos compostos |
| DK2529622T3 (en) | 2006-09-22 | 2018-05-07 | Pharmacyclics Llc | INHIBITORS OF BRUTON-TYROSINKINASE |
| HRP20151386T1 (hr) | 2007-03-12 | 2016-02-26 | Ym Biosciences Australia Pty Ltd | Fenil aminopirimidinski spojevi i njihova primjena |
| US8394794B2 (en) | 2007-03-23 | 2013-03-12 | Regents Of The University Of Minnesota | Therapeutic compounds |
| PE20090717A1 (es) | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| BRPI0909040B8 (pt) | 2008-03-11 | 2021-05-25 | Incyte Holdings Corp | derivados de azetidina e ciclobutano, seus usos, e composição |
| US8338439B2 (en) | 2008-06-27 | 2012-12-25 | Celgene Avilomics Research, Inc. | 2,4-disubstituted pyrimidines useful as kinase inhibitors |
| WO2014074661A1 (en) | 2012-11-08 | 2014-05-15 | Bristol-Myers Squibb Company | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHα RESPONSES |
| TWI620737B (zh) | 2012-11-08 | 2018-04-11 | 必治妥美雅史谷比公司 | 作爲ＩＬ－１２、ＩＬ－２３及／或ＩＦＮα反應調節劑之經烷基－醯胺取代之吡啶化合物 |
| WO2015089143A1 (en) | 2013-12-10 | 2015-06-18 | Bristol-Myers Squibb Company | Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses |
| CA2940666C (en) | 2014-02-28 | 2022-08-23 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
| CR20160512A (es) | 2014-05-01 | 2016-12-21 | Novartis Ag | Compuestos y composiciones como agonistas del receptor tipo toll 7 |
| WO2018031434A1 (en) | 2016-08-08 | 2018-02-15 | Merck Patent Gmbh | Tlr7/8 antagonists and uses thereof |
| TWI825663B (zh) * | 2016-10-14 | 2023-12-11 | 美商林伯士拉克許米公司 | Tyk2抑制劑及其用途 |
| EP3538513A1 (en) | 2016-11-11 | 2019-09-18 | Dynavax Technologies Corporation | Toll-like receptor antagonist compounds and methods of use |
| CA3120866A1 (en) | 2018-11-30 | 2020-06-04 | Nimbus Lakshmi, Inc. | Tyk2 inhibitors and uses thereof |
-
2019
- 2019-11-27 CA CA3120866A patent/CA3120866A1/en active Pending
- 2019-11-27 AU AU2019389025A patent/AU2019389025B2/en active Active
- 2019-11-27 EP EP19888308.4A patent/EP3886843A4/en active Pending
- 2019-11-27 JP JP2021530887A patent/JP7530360B2/ja active Active
- 2019-11-27 US US16/697,371 patent/US11053241B2/en active Active
- 2019-11-27 WO PCT/US2019/063510 patent/WO2020112937A1/en not_active Ceased
- 2019-11-27 CN CN201980087661.3A patent/CN113271938A/zh active Pending
-
2021
- 2021-05-14 US US17/320,394 patent/US11834449B2/en active Active
- 2021-05-24 IL IL283409A patent/IL283409A/en unknown
-
2024
- 2024-07-26 JP JP2024120957A patent/JP2024160253A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7530360B2 (ja) | 2024-08-07 |
| AU2019389025B2 (en) | 2025-07-24 |
| CN113271938A (zh) | 2021-08-17 |
| EP3886843A1 (en) | 2021-10-06 |
| EP3886843A4 (en) | 2022-08-31 |
| JP2022509260A (ja) | 2022-01-20 |
| US11834449B2 (en) | 2023-12-05 |
| JP2024160253A (ja) | 2024-11-13 |
| US20220106306A1 (en) | 2022-04-07 |
| US20200172540A1 (en) | 2020-06-04 |
| CA3120866A1 (en) | 2020-06-04 |
| AU2019389025A1 (en) | 2021-06-17 |
| WO2020112937A1 (en) | 2020-06-04 |
| US11053241B2 (en) | 2021-07-06 |
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