IL277103B2 - Igg stimulated remyelination of peripheral nerves - Google Patents
Igg stimulated remyelination of peripheral nervesInfo
- Publication number
- IL277103B2 IL277103B2 IL277103A IL27710320A IL277103B2 IL 277103 B2 IL277103 B2 IL 277103B2 IL 277103 A IL277103 A IL 277103A IL 27710320 A IL27710320 A IL 27710320A IL 277103 B2 IL277103 B2 IL 277103B2
- Authority
- IL
- Israel
- Prior art keywords
- polyclonal igg
- administered
- neuropathy
- igg
- mammal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261605117P | 2012-02-29 | 2012-02-29 | |
| PCT/US2013/028350 WO2013130826A2 (en) | 2012-02-29 | 2013-02-28 | Igg stimulated remyelination of peripheral nerves |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL277103A IL277103A (en) | 2020-10-29 |
| IL277103B1 IL277103B1 (en) | 2025-03-01 |
| IL277103B2 true IL277103B2 (en) | 2025-07-01 |
Family
ID=47884569
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL277103A IL277103B2 (en) | 2012-02-29 | 2013-02-28 | Igg stimulated remyelination of peripheral nerves |
| IL274512A IL274512B2 (en) | 2012-02-29 | 2013-02-28 | IgG-stimulated remodeling of peripheral nerve myelin |
| IL234303A IL234303B (en) | 2012-02-29 | 2014-08-26 | IgG-stimulated peripheral nerve myelin remyelination |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL274512A IL274512B2 (en) | 2012-02-29 | 2013-02-28 | IgG-stimulated remodeling of peripheral nerve myelin |
| IL234303A IL234303B (en) | 2012-02-29 | 2014-08-26 | IgG-stimulated peripheral nerve myelin remyelination |
Country Status (21)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3590960T3 (fi) * | 2012-02-29 | 2023-04-25 | Takeda Pharmaceuticals Co | Perifeeristen hermojen IgG-stimuloitu remyelinaatio |
| US9690975B2 (en) * | 2015-05-28 | 2017-06-27 | Axogen Corporation | Quantitative structural assay of a nerve graft |
| US11511136B2 (en) | 2017-11-17 | 2022-11-29 | The Research Foundation For The State University Of New York | Method for treating damaged peripheral nerves using x-ray microbeam irradiation |
| EP3908256A4 (en) * | 2019-01-07 | 2022-09-21 | Mallinckrodt Ard IP Unlimited Company | METHOD TO PROMOTE REMYELINATION |
| GB201907882D0 (en) | 2019-06-03 | 2019-07-17 | Cyprus Foundation For Muscular Dystrophy Res | Methods |
| EP4737584A1 (en) * | 2023-06-30 | 2026-05-06 | FUJIFILM Corporation | Method for evaluating intercellular interaction of neuroinflammation |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE348942B (cg-RX-API-DMAC10.html) | 1970-06-02 | 1972-09-18 | Statens Bakteriologiska Labor | |
| AT376367B (de) | 1983-03-16 | 1984-11-12 | Immuno Ag | Verfahren zur herstellung von therapeutisch verabreichbaren, in endbehaeltern abgefuellten plasmaderivaten |
| DK166763B1 (da) | 1983-03-16 | 1993-07-12 | Immuno Ag | Immunoglobulin-g-holdig fraktion |
| ATE36457T1 (de) | 1983-05-02 | 1988-09-15 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen krankheitserregern. |
| AT389815B (de) | 1984-03-09 | 1990-02-12 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten |
| AT390560B (de) | 1986-05-30 | 1990-05-25 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern |
| JP2871709B2 (ja) | 1988-11-21 | 1999-03-17 | 住友製薬株式会社 | 免疫グロブリンｇ結合活性を有する新規な蛋白質プロテインｈ、該蛋白質をコードする遺伝子及び該蛋白質の製造法 |
| US5177194A (en) | 1990-02-01 | 1993-01-05 | Baxter International, Inc. | Process for purifying immune serum globulins |
| WO1992003536A1 (en) * | 1990-08-15 | 1992-03-05 | University Of Miami And Its School Of Medicine | Autotransplantation of schwann cells to promote nervous system repair |
| AT402891B (de) | 1991-06-20 | 1997-09-25 | Immuno Ag | Verfahren zur herstellung eines inaktivierten blutproduktes |
| EP0674531A1 (de) | 1992-12-16 | 1995-10-04 | IMMUNO Aktiengesellschaft | Verfahren zur herstellung eines virussicheren biologischen präparates |
| FR2706466B1 (fr) | 1993-06-14 | 1995-08-25 | Aetsrn | Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré. |
| HRP940645A2 (en) | 1993-10-06 | 1996-12-31 | Immuno Ag | Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained |
| TW491855B (en) | 1996-08-07 | 2002-06-21 | Csl Ltd | Purification of immunoglobulins |
| US5886154A (en) | 1997-06-20 | 1999-03-23 | Lebing; Wytold R. | Chromatographic method for high yield purification and viral inactivation of antibodies |
| ID27417A (id) | 1998-06-09 | 2001-04-05 | Statens Seruminstitut | Proses untuk memproduksi immunoglobulin untuk pemberian melalui intravena dan produk-produk immunoglobulin lainnya |
| SE0001128D0 (sv) | 2000-03-30 | 2000-03-30 | Amersham Pharm Biotech Ab | A method of producing IgG |
| EP2287190B1 (en) * | 2000-05-10 | 2014-12-17 | Mayo Foundation For Medical Education And Research | Human igm antibodies with the capability of inducing remyelination, and diagnostic and therapeutic uses thereof particularly in the central nervous system |
| FR2824568B1 (fr) | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| JP2003070465A (ja) * | 2001-08-31 | 2003-03-11 | Keio Gijuku | シュワン細胞の培養方法 |
| JP2007521249A (ja) | 2003-01-24 | 2007-08-02 | エラン ファーマシューティカルズ，インコーポレイテッド | 脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療 |
| US20070244305A1 (en) | 2004-01-30 | 2007-10-18 | Suomen Punainen Risti Veripalvelu | Process for The Manufacture of Virus Safe Immunoglobulin |
| CA2557229C (en) | 2004-02-27 | 2012-07-10 | Octapharma Ag | A method of providing a purified, virus safe antibody preparation |
| EA017403B1 (ru) * | 2007-02-02 | 2012-12-28 | Байоджен Айдек Эмэй Инк. | Использование семафорина 6а в качестве промотора миелинизации и дифференцировки олигодендроцитов |
| US7854703B2 (en) | 2007-09-25 | 2010-12-21 | Intel Corporation | Peripheral neuropathy detection |
| CA2643496C (en) | 2008-11-06 | 2015-02-03 | Michael Fehlings | The therapeutic use of igg as a neuroprotective agent |
| CN102021140B (zh) * | 2009-09-18 | 2013-04-24 | 上海市第一人民医院 | 一种分离、纯化许旺细胞的方法 |
| FI3590960T3 (fi) * | 2012-02-29 | 2023-04-25 | Takeda Pharmaceuticals Co | Perifeeristen hermojen IgG-stimuloitu remyelinaatio |
-
2013
- 2013-02-28 FI FIEP19180237.0T patent/FI3590960T3/fi active
- 2013-02-28 ES ES19180237T patent/ES2943585T3/es active Active
- 2013-02-28 BR BR112014021240A patent/BR112014021240A2/pt not_active Application Discontinuation
- 2013-02-28 KR KR1020227011045A patent/KR102673154B1/ko active Active
- 2013-02-28 PT PT137096756T patent/PT2820042T/pt unknown
- 2013-02-28 CN CN201380021280.8A patent/CN104302666A/zh active Pending
- 2013-02-28 EA EA201400966A patent/EA032000B1/ru not_active IP Right Cessation
- 2013-02-28 DK DK13709675T patent/DK2820042T3/da active
- 2013-02-28 MX MX2014010387A patent/MX369444B/es active IP Right Grant
- 2013-02-28 WO PCT/US2013/028350 patent/WO2013130826A2/en not_active Ceased
- 2013-02-28 CN CN201910611688.XA patent/CN110343171A/zh active Pending
- 2013-02-28 CN CN201910008205.7A patent/CN109966488A/zh active Pending
- 2013-02-28 EA EA201892521A patent/EA201892521A1/ru unknown
- 2013-02-28 NZ NZ629867A patent/NZ629867A/en unknown
- 2013-02-28 KR KR1020147027130A patent/KR102170615B1/ko active Active
- 2013-02-28 JP JP2014560045A patent/JP6335800B2/ja active Active
- 2013-02-28 AU AU2013203088A patent/AU2013203088B2/en active Active
- 2013-02-28 IL IL277103A patent/IL277103B2/en unknown
- 2013-02-28 DK DK19180237.0T patent/DK3590960T3/da active
- 2013-02-28 IL IL274512A patent/IL274512B2/en unknown
- 2013-02-28 SG SG11201405302WA patent/SG11201405302WA/en unknown
- 2013-02-28 CN CN201710896364.6A patent/CN107551269A/zh active Pending
- 2013-02-28 KR KR1020207030277A patent/KR20200126005A/ko not_active Ceased
- 2013-02-28 PL PL13709675T patent/PL2820042T3/pl unknown
- 2013-02-28 PL PL19180237.0T patent/PL3590960T3/pl unknown
- 2013-02-28 EP EP19180237.0A patent/EP3590960B1/en active Active
- 2013-02-28 US US13/781,283 patent/US8986670B2/en active Active
- 2013-02-28 ES ES13709675T patent/ES2755056T3/es active Active
- 2013-02-28 PT PT191802370T patent/PT3590960T/pt unknown
- 2013-02-28 EP EP13709675.6A patent/EP2820042B1/en active Active
- 2013-03-01 TW TW106122004A patent/TWI700297B/zh active
- 2013-03-01 TW TW107124197A patent/TW201838654A/zh unknown
- 2013-03-01 AR ARP130100662A patent/AR090211A1/es not_active Application Discontinuation
- 2013-03-01 TW TW102107471A patent/TWI632158B/zh active
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2014
- 2014-08-26 IL IL234303A patent/IL234303B/en active IP Right Grant
- 2014-08-28 MX MX2019012496A patent/MX2019012496A/es unknown
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2015
- 2015-02-18 US US14/625,542 patent/US9834593B2/en active Active
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2016
- 2016-02-23 AU AU2016201137A patent/AU2016201137B2/en active Active
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2017
- 2017-09-13 JP JP2017175330A patent/JP6637934B2/ja active Active
- 2017-10-30 US US15/798,313 patent/US10494418B2/en active Active
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2018
- 2018-01-02 AU AU2018200026A patent/AU2018200026B2/en active Active
- 2018-06-25 HK HK18108139.5A patent/HK1248534A1/zh unknown
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2019
- 2019-10-04 JP JP2019183415A patent/JP6979990B2/ja active Active
- 2019-10-18 US US16/657,920 patent/US20200216518A1/en not_active Abandoned
- 2019-11-28 AR ARP190103486A patent/AR117207A2/es unknown
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2021
- 2021-06-14 US US17/347,380 patent/US20210300997A1/en not_active Abandoned
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